A New Look at Meningomyeloceles

التفاصيل البيبلوغرافية
العنوان: A New Look at Meningomyeloceles
المؤلفون: Gordon Worley
المصدر: Pediatrics. 111:1494-1495
بيانات النشر: American Academy of Pediatrics (AAP), 2003.
سنة النشر: 2003
مصطلحات موضوعية: medicine.medical_specialty, Pregnancy, Fetal surgery, business.industry, Spina bifida, General surgery, medicine.medical_treatment, Gold standard, Gestational age, medicine.disease, Shunt (medical), Hydrocephalus, Pediatrics, Perinatology and Child Health, medicine, business, Cohort study
الوصف: To the Editor .— Rintoul et al1 reviewed the records of 297 patients born after 1983 with an open meningomyelocele whose lesion was closed at their hospital and who were subsequently followed in their spina bifida clinic, to describe clinical outcomes. The authors are to be commended for documenting the results of conscientious and comprehensive care. I have, however, reservations about using their cross-sectional survey for their stated purpose “to serve as a comparison group … to assess the efficacy” of in utero (fetal) surgery for meningomyelocele. First, I do not believe that their rate of placement of a ventriculoperitoneal (VP) shunt for treatment of hydrocephalus (81%) or that from any cross-sectional survey can serve as a “gold standard” against which the rate of developing hydrocephalus after fetal surgery can be compared. The decision about who among infants with spina bifida and hydrocephalus requires placement of a VP shunt is arbitrary and the prevalence of shunting varies from clinic to clinic. For instance, in a cohort study performed by our clinic some years ago, we found that 95% of patients had been shunted.2 Likewise, there is a significant difference in the rate of VP shunt placement in the 2 series of patients who underwent fetal surgery for meningomyelocele, as acknowledged by the authors. In the series of patients who had fetal surgery reported from the authors’ institution, reported by Sutton et al,3 only 1 of 9 (11%) had VP shunt placement, but Bruner et al,4 doing fetal surgery on patients at a slightly more advanced gestational age, shunted 59%. We now follow a patient who had fetal …
تدمد: 1098-4275
0031-4005
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1bd9bc715f035475aa47789e5d6ebb25Test
https://doi.org/10.1542/peds.111.6.1494Test
رقم الانضمام: edsair.doi...........1bd9bc715f035475aa47789e5d6ebb25
قاعدة البيانات: OpenAIRE