التفاصيل البيبلوغرافية
| العنوان: |
Long-term Outcome of Schilder Disease Treated With Interferon-β. |
| المؤلفون: |
Wei-Sheng Lin1, Meng-Fai Kuo2, Shinn-Forng Peng, Steven3, Pi-Chuan Fan4 pcfan6@ntu.edu.tw |
| المصدر: |
Pediatrics. Nov2019, Vol. 144 Issue 5, p1-5. 5p. |
| مصطلحات موضوعية: |
*THERAPEUTIC use of interferons, *AGE factors in disease, *DEMYELINATION, *PATIENT aftercare, *TREATMENT effectiveness, *DISEASE remission, DISEASE relapse prevention |
| مستخلص: |
Schilder disease, also termed diffuse myelinoclastic sclerosis, is characterized by a large demyelinating lesion involving 1 or both sides of the centrum semiovale of the cerebral hemispheres. It often presents with tumorlike features and poses a diagnostic challenge. Schilder disease can be monophasic or relapsing, and disease-modifying therapy for the latter scenario is largely empirical. Here, we report a 14-year-old girl with relapsing Schilder disease within 1 year after disease onset. She has been followed-up for nearly 10 years and remains in sustained remission ever since interferon-b therapy was prescribed after the second attack. In this case study, it is suggested that interferon-b may induce long-term remission in relapsing Schilder disease and is therefore worth considering in this regard. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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