دورية أكاديمية
High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old
| العنوان: | High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old |
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| المؤلفون: | Yin, Zhao-Xue, Shi, Xiao-Ming, Kraus, Virginia B., Fitzgerald, Simon M., Qian, Han-zhu, Xu, Jian-wei, Zhai, Yi, Sereny, Melanie D., Zeng, Yi |
| المساهمون: | Shi, XM (reprint author), Chinese Ctr Dis Control & Prevent, Div Noncommunicable Dis Control & Community Hlth, 155 Changbai Rd, Beijing 102206, Peoples R China., Chinese Ctr Dis Control & Prevent, Div Noncommunicable Dis Control & Community Hlth, Beijing 102206, Peoples R China., Duke Univ, Dept Med, Durham, NC 27710 USA., Vanderbilt Univ, Vanderbilt Inst Global Hlth, Nashville, TN 37203 USA., Duke Univ, Dept Sociol, Durham, NC 27701 USA., Duke Univ, Ctr Study Aging & Human Dev, Durham, NC 27710 USA., Duke Univ, Div Geriatr, Sch Med, Durham, NC 27710 USA., Peking Univ, Natl Sch Dev, Ctr Study Healthy Aging & Dev Studies, Beijing 100871, Peoples R China., Chinese Ctr Dis Control & Prevent, Div Noncommunicable Dis Control & Community Hlth, 155 Changbai Rd, Beijing 102206, Peoples R China. |
| المصدر: | SCI |
| بيانات النشر: | age and ageing |
| سنة النشر: | 2012 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | triglycerides, cognitive function, lipids, oldest-old, elderly, BLOOD-BRAIN-BARRIER, MINI-MENTAL-STATE, ALZHEIMERS-DISEASE, LIPOPROTEIN LEVELS, LIPID LEVELS, FATTY-ACIDS, IMPAIRMENT, DEMENTIA, OBESITY, RISK |
| الوصف: | Design: multivariate statistical analysis using cross-sectional data. Setting: community-based setting in longevity areas in China. Subjects: eight hundred and thirty-six subjects aged 80 and older were included in the sample. Methods: plasma total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood pressure and fasting plasma glucose were measured and information about demographics and lifestyle was collected. Cognitive status was assessed using the Mini-Mental State Examination (MMSE). Results: cumulative logit model analysis showed that triglyceride was significantly negatively associated with cognitive impairment. By general linear modelling, there was a significant linear trend of MMSE scores with the level of triglyceride, but not with levels of cholesterol after adjustment. The odds ratio (OR) of cognitive impairment (MMSE score < 18) was significantly reduced for the highest quartile of plasma triglyceride concentration (OR: 0.52, 95% CI: 0.33-0.84), but not for the second or third quartile, compared with the lowest quartile (adjusted models). There were no significant associations between cognitive impairment and cholesterol. Conclusion: we concluded that high normal plasma triglyceride was associated with preservation of cognitive function while lower concentrations were not in the Chinese oldest-old. ; Geriatrics & Gerontology ; SCI(E) ; SSCI ; 7 ; ARTICLE ; 5 ; 600-606 ; 41 |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | English |
| ردمك: | 978-0-00-308011-7 0-00-308011-0 |
| تدمد: | 0002-0729 |
| العلاقة: | AGE AND AGEING.2012,41,(5),600-606.; 869770; http://hdl.handle.net/20.500.11897/392999Test; WOS:000308011000009 |
| DOI: | 10.1093/ageing/afs033 |
| الإتاحة: | https://doi.org/20.500.11897/392999Test https://doi.org/10.1093/ageing/afs033Test https://hdl.handle.net/20.500.11897/392999Test |
| رقم الانضمام: | edsbas.F1A2E2CB |
| قاعدة البيانات: | BASE |
Full Text Finder | ردمك: | 9780003080117 0003080110 |
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| تدمد: | 00020729 |
| DOI: | 10.1093/ageing/afs033 |