دورية أكاديمية
Morphological Audit of glomerular diseases in a tertiary care Hospital.
| العنوان: | Morphological Audit of glomerular diseases in a tertiary care Hospital. |
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| المؤلفون: | Maria Shafique, Uzma Bukhari, Suresh Kumar, Anita George, Asma Bukhari, Mehwish Sajjad |
| المصدر: | International Journal of Endorsing Health Science Research, Vol 9, Iss 4 (2022) |
| بيانات النشر: | Advance Educational Institute & Research Centre, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Focal Segmental Glomerulosclerosis, Membranous Glomerulonephritis, Mesangiocapillary Glomerulonephritis, Pre-Spike Membranous Glomerulonephritis, Immunofluorescence, Silver Stain., Medicine |
| الوصف: | Background: Glomerular diseases are a universal health issue, and Pakistan ranks eighth in renal disease, causing 20,000 deaths every year. Renal biopsy is a valuable diagnostic tool and provides prognostic insight and therapeutic plans. The study's objective is to determine the frequency and pattern of various glomerulopathies concerning age and gender. Methodology: A cross-sectional study was performed at the Department of Pathology, Ziauddin Medical University, and Hospital, Karachi, from 19th December 2018 to 15th April 2019. A total of 91 patients were included of either gender with a clinical history of glomerulonephritis. All biopsy samples were analyzed by using light and immunofluorescence microscopy techniques. Patient data were compiled and analyzed through SPSS version 20.0. Results: A total of 91 cases of the renal biopsy were evaluated; 51.6% of these cases were male patients. Forty-nine (53.8%) cases were reported as focal segmental glomerulosclerosis, 35(38.5%) were diagnosed with membranous glomerulonephritis, and 7(7.7%) were reported as mesangiocapillary glomerulonephritis. In membranous glomerulonephritis, 7.7% were pre-spike membranous glomerulonephritis. In the current study, 35.2% of cases showed diffuse glomerular basement membrane (GBM) thickening with spikes, and 4.4% showed GBM thickening with focal spikes on silver stain. Conclusion: Glomerular diseases are slightly more prevalent in males than females. The most commonly diagnosed primary glomerulonephritis was focal segmental glomerulosclerosis, followed by membranous glomerulonephritis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2307-3748 2310-3841 |
| العلاقة: | http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/797Test; https://doaj.org/toc/2307-3748Test; https://doaj.org/toc/2310-3841Test |
| الوصول الحر: | https://doaj.org/article/d0a8e40618d841fb98ddf1be1469a26dTest |
| رقم الانضمام: | edsdoj.0a8e40618d841fb98ddf1be1469a26d |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 23073748 23103841 |
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