دورية أكاديمية
Osteoporosis: Economic Burden of Disease in Italy
| العنوان: | Osteoporosis: Economic Burden of Disease in Italy |
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| المؤلفون: | Marcellusi, A, Rotundo, MA, Nardone, C, Sciattella, P, Gazzillo, S, Rossini, M, Barbagallo, M, Antenori, A, Valle, D, Mennini, FS |
| المساهمون: | Marcellusi, A, Rotundo, M, Nardone, C, Sciattella, P, Gazzillo, S, Rossini, M, Barbagallo, M, Antenori, A, Valle, D, Mennini, F |
| بيانات النشر: | ADIS INT LTD |
| سنة النشر: | 2020 |
| المجموعة: | Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca |
| مصطلحات موضوعية: | Aged, Female, Health Care Costs, Hospitalization, Humans, International Classification of Diseases, Italy, Male, Middle Aged, Osteoporosis, Patient Discharge, State Medicine, Cost of Illness, Settore SECS-P/06 - ECONOMIA APPLICATA, Settore MED/42 - IGIENE GENERALE E APPLICATA |
| الوصف: | Background and Objective Today, osteoporosis is the most common bone disease and an important public health problem in all developed countries. The objective of this study was to estimate the costs associated with the management and treatment of osteoporosis in order to assess the economic burden in Italy for 2017, in terms of direct medical costs and social security costs. Methods A cost of illness model was developed to estimate the average cost per year sustained by the NHS (National Health Service) and Social Security System in Italy. A systematic literature review was performed to obtain epidemiological, direct and indirect costs parameters where available. Hospitalisation costs were calculated considering the administrative database of the hospital discharge records for the period 2008-2016. Patients were enrolled in the analysis if they report the subsequent inclusion criteria: age >= 45 years and presence of osteoporosis in primary or secondary diagnosis (ICD9-CM 733.0) and/or presence of a major fracture in primary or secondary diagnosis (excluding road accidents) in the following locations: spine (codes ICD9-CM: 805;806), femur (codes ICD9-CM: 820; 821), radius and ulna (codes ICD9-CM: 813.4; 813.5), humerus (codes ICD9-CM: 812.0-812.5), pelvis (code ICD9-CM: 808), tibia and fibula (codes ICD9-CM: 823), ankle (code ICD9: 824) and ribs (codes ICD9-CM: 807.0; 807.1). Costs were estimated considering the diagnosis-related group (DRG) national tariff associated with each hospitalisation. Finally, the administrative databases of the Italian National Social Security Institute (INPS) (2009-2015) were analysed for the estimate the pension and disability costs from the social perspective. Results The model estimated an average annual economic burden of osteoporosis in Italy of euro2.2 billion. Of this cost, approximately 80% (euro1.8 billion) was associated with hospitalisations, 16% (euro351 million) for pharmacological treatments, 3% (euro71 million) for ambulatory visits, and 0.6% (euro13 million) for ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/32248346; info:eu-repo/semantics/altIdentifier/wos/WOS:000523408200001; volume:40; issue:5; firstpage:449; lastpage:458; numberofpages:10; journal:CLINICAL DRUG INVESTIGATION; http://hdl.handle.net/2108/255946Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85083853004 |
| DOI: | 10.1007/s40261-020-00904-8 |
| الإتاحة: | https://doi.org/10.1007/s40261-020-00904-8Test http://hdl.handle.net/2108/255946Test |
| حقوق: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.C917C443 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s40261-020-00904-8 |
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