دورية أكاديمية
Could Rolandic spikes be a prognostic factor of the neurocognitive outcome of children with BECTS?
| العنوان: | Could Rolandic spikes be a prognostic factor of the neurocognitive outcome of children with BECTS? |
|---|---|
| المؤلفون: | Tristano I., Nicita F., Garone G., Ursitti F., Nardone C., Rocchi V., Guido C. A., Spalice A. |
| المساهمون: | Tristano, I., Nicita, F., Garone, G., Ursitti, F., Nardone, C., Rocchi, V., Guido, C. A., Spalice, A. |
| بيانات النشر: | Academic Press Inc. 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA |
| سنة النشر: | 2018 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | BECTS, Neurocognitive, Rolandic spike, Working memory, Adolescent, Case-Control Studie, Child, Preschool, Cognition, Cognition Disorder, Electroencephalography, Epilepsy, Rolandic, Female, Human, Magnetic Resonance Imaging, Male, Memory, Short-Term, Prognosi, Wechsler Scale, Mental Status and Dementia Tests |
| الوصف: | Introduction: Rolandic epilepsy, also known as benign childhood epilepsy with centrotemporal spikes (BECTS), is one of the most common epileptic syndromes in previously healthy children. Despite what was known about the benignity of this syndrome, there is always more evidence about the involvement of the cognitive functions with different deficits in several domains to be investigated. Aim of the study: The aim of our study was to describe prognostic electroencephalogram (EEG) pattern of an adverse cognitive development to recognize patients at higher risk of lasting cognitive deficits that could need antiepileptic drugs (AEDs) or an improved neurocognitive therapy. In addition, we wanted to investigate the existence of a possible linkage between the number of interictal epileptiform discharges (IEDs) in the EEG and the more pronounced cognitive deficits. Material and methods: We performed a case–control study on a cohort of 16 patients (10 male and 6 female) aged 4–14, diagnosed with BECTS who underwent EEG, magnetic resonance imaging (MRI), and neurocognitive assessment at the Pediatric Neurology Unit at the Umberto I Hospital, Sapienza University of Rome. Patients were divided into two groups according to the percentage of IEDs evaluated based on their sleep EEG: group A with less than 50% of the entire EEG invaded by discharges in more than 70% of the total number of EEG performed, so-called with low or intermediate activation. On the contrary, group B had a high activation, with more than 50% of the entire EEG invaded by discharges in the same percentage of the EEG performed. All children were assessed based on a protocol designed to study neuropsychological functions with specific tests chosen depending on age (Wechsler Intelligence Scale for Children IV: WISC IV; Wechsler Preschool and Primary Scale of Intelligence III: WPPSI III). Groups were compared for cognitive outcomes achieved by each patient through Student's t-test with a significance level of p < 0.05 (two-tailed). Results: There is no ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/30031676; info:eu-repo/semantics/altIdentifier/wos/WOS:000442624500025; volume:86; firstpage:157; lastpage:162; numberofpages:6; journal:EPILEPSY & BEHAVIOR; http://hdl.handle.net/11573/1463752Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85050165085 |
| DOI: | 10.1016/j.yebeh.2018.03.022 |
| الإتاحة: | https://doi.org/10.1016/j.yebeh.2018.03.022Test http://hdl.handle.net/11573/1463752Test |
| رقم الانضمام: | edsbas.52DE5894 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.yebeh.2018.03.022 |
|---|