التفاصيل البيبلوغرافية
| العنوان: |
Seasonal response of the synergism of maternal comorbidities and long-term air pollution exposure on birth outcomes. |
| المؤلفون: |
Zhao, Boyi, Wang, Min, Lü, Changwei, Feng, Ling, Ma, Hua, Meng, Haixia, Qi, Muge, Fan, Qingyun, Wang, Haoji, Zhou, Haijun, He, Jiang |
| المصدر: |
Ecotoxicology & Environmental Safety; Mar2020, Vol. 191, pN.PAG-N.PAG, 1p |
| مصطلحات موضوعية: |
AIR pollution, COMORBIDITY, PREECLAMPSIA, AIR pollutants, PREMATURE labor, CHILDBIRTH |
| مستخلص: |
Air pollution has been considered as one of the most important factors associating with various birth outcomes. However, the seasonal response of maternal comorbidities effects associated with air pollution has not been investigated, especially in the city with distinguish seasonal pattern and long heating seasons. In this work, 69,945 live births were investigated from 2013 to 2016, and the seasonal relationship between air pollution and preterm birth and low birth weight were assessed, as well as the synergism of maternal comorbidities. Exposures of six pollutants were assigned to maternal residences during pregnancy. The potential effect modification by maternal comorbidities on the associations was evaluated between prenatal air pollution and preterm birth (PTB), as well as effects of seasons and trimesters. Adjusting for seasonality, all six pollutants presented seasonal relationship with preterm birth, which CO, PM 10 , NO 2 , and PM 2.5 were with [odds ratio (OR) = 1.035 95% CI: 1.015, 1.055, OR = 1.039 95% CI: 1.034, 1.045, OR = 1.042, 95% CI: 1.029, 1.056 and OR = 1.085 95% CI 1.073, 1.097, respectively] for tenth quartile of 10 μg/m3 range increased in autumn (the beginning of heating season). For O 3 , it associated with PTB in winter and spring with OR = 1.113 95% CI: 1.104, 1.123, and OR = 1.155 95% CI: 1.145, 1.165, respectively. The OR increase of PTB for exposure to all six pollutants was higher among women with preeclampsia and gestational hypertension. The associations between ambient air pollution and preterm birth were modified by gestational hypertension and preeclampsia. The seasonal patterns of six studied air pollutants increases the risk of PTB in autumn and winter distinguishably, which may due to the sudden increased concentrations of pollutants emitted by traditional heating. The seasonal response of the synergism of maternal comorbidities and long-term air pollution exposure on birth outcomes is supported by the data sets of preterm birth. Image 1 • The seasonal response of maternal comorbidities effects with air pollution was investigated. • The associations between air pollution and PTB were modified by gestational hypertension and preeclampsia. • The seasonal patterns of six studied air pollutants increased the risk of PTB in autumn and winter distinguishably. • The seasonal response of PTB associated with the synergism of maternal comorbidities and long-term air pollution exposure. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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