المؤلفون: Kummer, Arthur, Cardoso, Francisco, Teixeira, Antonio Lucio

المصدر: Arquivos de Neuro-Psiquiatria. August 2010 68(4)

مصطلحات موضوعية: Parkinson's disease, anxiety, generalized anxiety disorder, rating scales, psychometrics, clinimetrics

الوصف: Anxiety is common in Parkinson's disease (PD), but studies concerning specific anxiety disorders are scarce. Essential psychometric properties of anxiety rating scales are also lacking. OBJECTIVE: To investigate general anxiety disorder (GAD) in PD and psychometric properties of the Hamilton Anxiety Rating Scale (Ham-A). METHOD: Ninety-one PD patients underwent neurological and psychiatric examination, which included the MINI-Plus, the Ham-A and the Hamilton Depression Rating Scale (Ham-D). RESULTS: GAD was present in 30.8% of PD patients. Patients with GAD had longer disease duration (p=0.044) and were in use of higher doses of levodopa (p=0.034). They also tended to have more motor fluctuations and dyskinesias. The group with GAD scored higher in Ham-A (p<0.001), in the somatic (p=0.004) and psychic (p<0.001) subscales of Ham-A, and in Ham-D (p=0.004). The Ham-A showed good internal consistency (Cronbach's alpha=0.893) and a cutoff score of 10/11 is suggested to screen for GAD. CONCLUSION: GAD is frequent in PD and the Ham-A may be a useful instrument to screen for this disorder.

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المؤلفون: Ferreira, Liliani Souza dos Santos, Pereira, Cristiana Borges, Rossini, Sueli, Kanashiro, Aline Mizuta Kozoroski, Adda, Carla Cristina, Scaff, Milberto

المصدر: Arquivos de Neuro-Psiquiatria. April 2010 68(2)

مصطلحات موضوعية: dizziness, phobic postural vertigo, mood disorder, anxiety disorder

الوصف: Phobic postural vertigo (PPV) is a frequent diagnosis which can be challenging to treat. OBJECTIVE: To investigate the presence of psychiatric disturbances in patients with PPV; to assess the psychological status of patients using adaptive diagnosis; to verify possible correlations between severity of psychiatric disturbance and adaptive efficacy. METHOD: A total of nineteen subjects were assessed and two instruments applied: the Primary Care Evaluation of Mental Disorders Questionnaire (PRIME-MD) and the Adaptive Operationalized Diagnostic Scale (AODS), and results from both tests were compared. RESULTS: Fourteen patients presented with mood disorder and thirteen with anxiety. All patients presented compromised adaptive efficacy. Correlation was found between overall outcome on the PRIME and the AODS (tau= -0.42, p=0.027), Separate analysis revealed correlation between results of the AODS and anxiety disorders (tau= -0.45, p=0.018) but not with mood disorders (tau= -0.36, p=0.054). CONCLUSION: Adaptive compromise was observed in individuals with PPV which was shown to be associated to psychiatric disorders.

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المؤلفون: Valença, Alexandre M., Nardi, Antonio E., Mezzasalma, Marco A., Nascimento, Isabella, Lopes, Fabiana L., Zin, Walter A., Versiani, Marcio

المصدر: Arquivos de Neuro-Psiquiatria. June 2004 62(2b)

مصطلحات موضوعية: respiration, panic attack, norepinephrine, panic subtypes, anxiety disorder

الوصف: OBJECTIVE: Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype. METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine. RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks. CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.

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المؤلفون: Nardi, Antonio E., Nascimento, Isabella, Valença, Alexandre M., Lopes, Fabiana L., Mezzasalma, Marco A., Zin, Walter A.

المصدر: Arquivos de Neuro-Psiquiatria. September 2003 61(3B)

مصطلحات موضوعية: panic attacks, respiration, anxiety disorder, comorbidity, ventilation

الوصف: OBJECTIVE: Our aim was to observe if anxiety disorder patients - DSM-IV - respond in a similar way to the induction of panic attacks by a breath-holding challenge test. METHOD: We randomly selected 29 panic disorder (PD) patients, 27 social anxiety disorder (SAD) patients, 21 generalized anxiety disorder (GAD) patients. They were induced to breath-hold for as long as possible four times with two-minute interval between them. Anxiety scales were applied before and after the test. RESULTS: A total of 44.8% (n=13) PD patients, 14.8% (n=4) SAD patients, 9.5% (n=2) GAD patients had a panic attack after the test (c²= 21.44, df= 2, p=0.001). There was no heart rate or anxiety levels difference among the groups before and after the test. CONCLUSION: In this breath-holding challenge test the panic disorder patients were more sensitive than other anxiety disorder patients.

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المؤلفون: Nardi, Antonio E.

المصدر: Arquivos de Neuro-Psiquiatria. September 2001 59(3A)

مصطلحات موضوعية: social anxiety disorder, social phobia, pharmacologic treatment

الوصف: Social anxiety disorder (SAD) is a marked and persistent fear of doing almost everything in front of people due to concerns about being judge by others. An up-to-date review is needed in order to reach a practical judgement of all psychopharmacological data. Case reports, open and double-blind trials with SAD were described and commented upon from a clinical point of view. The MEDLINE system was searched from 1975 to 2001. The references from the selected papers were also used as a source. MAOIs (fenelzine, tranylcypromine), reversible monoamino oxidase-A inhibitors (moclobemide, brofaromine), SSRIs (paroxetine, sertraline, fluoxetine, fluvoxamine) and some other antidepressants (venlafaxine, nefazodone) have proven effective in several studies with various methodologies. The MAOIs have more serious adverse effects and the SSRIs have the best tolerance. SSRIs are efficacious and the first choice of treatment.

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المؤلفون: LACERDA, ACIOLY L.T., CAETANO, DORGIVAL, CAETANO, SHEILA C.

المصدر: Arquivos de Neuro-Psiquiatria. June 2000 58(2B)

مصطلحات موضوعية: cholesterol, generalized anxiety disorder, major depression, panic disorder

الوصف: Serum plasma total cholesterol levels were measured in 85 male or female outpatients with panic disorder (PD; N=41), generalized anxiety disorder (GAD; N=23) and major depression (MD; N=21) according to DSM-IV criteria. All the patients had a mean cholesterol level within the normal range; males (N=22) and females (N=63) had approximately the same serum cholesterol levels (p > .05). No significant differences in cholesterol levels emerged between PD, GAD and MD patient groups. Both female PD and female GAD subjects had a mean cholesterol level similar to their male counterparts (p>.05). It is concluded that both Hayward and colleagues and Bajwa et al. findings could not be replicated by our study.

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المؤلفون: NARD, ANTONIO EGIDIO, VALENÇA, ALEXANDRE M., NASCIMENTO, ISABELLA, MEZZASALMA, MARCO A., ZIN, WALTER

المصدر: Arquivos de Neuro-Psiquiatria. December 1999 57(4)

مصطلحات موضوعية: panic attack, respiration, anxiety disorder, ventilation

الوصف: Respiratory abnormalities are associated with anxiety, particularly with panic attacks. Symptoms such as shortness of breath, "empty-head" feeling, dizziness, paresthesias and tachypnea have been described in the psychiatric and respiratory physiology related to panic disorder. Panic disorder patients exhibit both behaviorally and physiologically abnormal responses to respiratory challenges tests. Objective: We aim to observe the induction of panic attacks by hyperventilation in a group of panic disorder patients (DSM-IV). Method: 13 panic disorder patients and 11 normal volunteers were randomly selected. They were drug free for a week. They were induced to hyperventilate (30 breaths/min) for 3 minutes. Anxiety scales were taken before and after the test. Results: 9 (69.2%) panic disorder patients and one (9.1%) of control subjects had a panic attack after hyperventilating (p< 0.05). Conclusion: The panic disorder group was more sensitive to hyperventilation than normal volunteers. The induction of panic attacks by vonluntary hyperventilation may be a useful and simple test for validating the diagnosis in some specific panic disorder patients.

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المؤلفون: Arthur Kummer, José Teotônio de Oliveira, Antônio Lúcio Teixeira, Rodrigo Santiago Gomez, Elizabeth Regina Comini Frota, Mariana Inés Ybarra

المصدر: Arquivos de Neuro-Psiquiatria v.69 n.2a 2011
Arquivos de neuro-psiquiatria
Academia Brasileira de Neurologia
instacron:ABNEURO
Arquivos de Neuro-Psiquiatria, Volume: 69, Issue: 2a, Pages: 176-179, Published: APR 2011
Arquivos de Neuro-Psiquiatria, Vol 69, Iss 2a, Pp 176-179 (2011)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Cross-sectional study, Neuropsychiatry, lcsh:RC321-571, Interview, Psychological, Myasthenia Gravis, Prevalence, Medicine, Humans, neuropsychiatry, Psychiatry, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Depression (differential diagnoses), myasthenia gravis, business.industry, Mental Disorders, depressão, medicine.disease, miastenia gravis, neuropsiquiaria, Mental health, Myasthenia gravis, Cross-Sectional Studies, Neurology, Socioeconomic Factors, depression, Anxiety, saúde mental, Female, Neurology (clinical), Psychiatric interview, medicine.symptom, business, Anxiety disorder, mental health

الوصف: OBJECTIVE: To investigate the prevalence of psychiatric disorders in patients with myasthenia gravis (MG). METHOD: Forty-one patients with MG answered to a structured psychiatric interview (MINI-Plus). RESULTS: Eleven (26.1%) patients were diagnosed with a depressive disorder and 19 (46.3%) were diagnosed with an anxiety disorder. Patients with dysthymia were older (p=0.029) and had longer disease duration (p=0.006). Patients with social phobia also had longer disease duration (p=0.039). CONCLUSION: Psychiatric disorders in MG are common, especially depressive and anxiety disorders. OBJETIVO: Investigar a prevalência de transtornos psiquiátricos em pacientes com miastenia gravis (MG). MÉTODO: Quarenta e um pacientes com MG responderam a uma entrevista psiquiátrica estruturada (MINI-Plus). RESULTADOS: Onze (26,1%) pacientes foram diagnosticados com transtorno depressivo e 19 (46,3%) foram diagnosticados com um transtorno de ansiedade. Pacientes com distimia eram mais velhos (p=0,029) e tinham maior tempo de doença (p=0,006). Os pacientes com fobia social também tiveram maior tempo de doença (p=0,039). CONCLUSÃO: Transtornos psiquiátricos na MG são bastante comuns, principalmente transtornos depressivos e de ansiedade.

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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000200006Test

المؤلفون: Marcia Rozenthal, Ana Claudia Rodrigues de Cerqueira, José Marcelo Ferreira Bezerra, Antonio Egidio Nardi

المصدر: Arquivos de Neuro-Psiquiatria v.68 n.4 2010
Arquivos de neuro-psiquiatria
Academia Brasileira de Neurologia
instacron:ABNEURO
Arquivos de Neuro-Psiquiatria, Volume: 68, Issue: 4, Pages: 659-661, Published: AUG 2010

مصطلحات موضوعية: musculoskeletal diseases, medicine.medical_specialty, animal structures, Generalized anxiety disorder, business.industry, Rigidity (psychology), Audiology, equipment and supplies, medicine.disease, Trunk, body regions, Neurology, medicine, Neurology (clinical), Psychiatry, business, Stiff person syndrome

الوصف: Stiff-person syndrome (SPS) also called stiff-man syndrome, is an immune-mediated CNS disorder characterized by progressive rigidity of the trunk and proximal limb muscles, associated with intermittent superimposed spasms and heightened sensitivity to external stimuli. The spasms are often triggered by emotions, such fear and unexpected tactile, auditory or emotional stimulation1 […] Stiff-Person syndrome and generalized anxiety disorder

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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000400036Test

المؤلفون: Ricardo Gorayeb, Maria Angela Marchini Gorayeb

المصدر: Arquivos de Neuro-Psiquiatria, Volume: 60, Issue: 3B, Pages: 764-768, Published: SEP 2002
Arquivos de Neuro-Psiquiatria v.60 n.3B 2002
Arquivos de neuro-psiquiatria
Academia Brasileira de Neurologia
instacron:ABNEURO
Arquivos de Neuro-Psiquiatria, Vol 60, Iss 3B, Pp 764-768 (2002)

مصطلحات موضوعية: medicine.medical_specialty, Population, High anxiety, lcsh:RC321-571, cefaléia, Epidemiology, medicine, infância, Psychiatry, education, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, childhood, education.field_of_study, High prevalence, Manifest Anxiety Scale, escolares, schoolchildren, medicine.disease, anxiety, ansiedade, Neurology, Anxiety, Neurology (clinical), medicine.symptom, Psychology, headache, Anxiety disorder

الوصف: Avaliaram-se 374 crianças de 8 a 13 anos de idade em escolas públicas de Ribeirão Preto, objetivando averiguar a prevalência de queixas de cefaléia e sua associação com indicadores de transtornos de ansiedade. Os pais responderam um questionário sobre a presença e frequência de cefaléia e de comportamentos/sintomas associados a transtornos de ansiedade. As crianças foram avaliadas através da escala de ansiedade "O que Penso e Sinto". Das 374 crianças, 45,4% nunca se queixaram de cefaléia; 41,2%, ocasionalmente e 13,5%, frequentemente. Entre aquelas que se queixam frequentemente de cefaléia, encontrou-se maior número de meninas, índice de ansiedade mais elevado e maior frequência de bruxismo e agitação. A alta prevalência de cefaléia na amostra e sua associação com maior frequência de bruxismo é compatível com dados epidemiológicos norte-americanos e brasileiros. Os resultados apontam para uma associação entre queixas frequentes de cefaléia e elevado índice de ansiedade. A sample of 374 public elementary and junior high school students aged 8 to 13 years were evaluated to assess the prevalence of frequent headache complaints, associated with indications of anxiety disorder. Parents answered a questionnaire to investigate the presence and frequency of headache and of behaviors/symptoms that might indicate the presence of anxiety disorders. Children were evaluated using the Revised Children's Manifest Anxiety Scale adapted to this population. Among them, 45.4% had never had a headache complaint; 41.2% had occasional headache complaints; and 13.5% had frequent headache complaints. Among children with frequent headache complaints there were more girls than boys, higher anxiety scores, higher occurrence of bruxism, and higher frequency of agitation. The high prevalence of headache and its association with bruxism in this sample is compatible with North American and Brazilian epidemiological data. Results show an association between frequent headache complaints and high anxiety scores.

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000500016&lng=en&tlng=enTest