دورية أكاديمية
Interobserver variability in the delineation of the primary lung cancer and lymph nodes on different four-dimensional computed tomography reconstructions
| العنوان: | Interobserver variability in the delineation of the primary lung cancer and lymph nodes on different four-dimensional computed tomography reconstructions |
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| المؤلفون: | Mercieca, S., Belderbos, J.S., Jaeger, K. de, Schinagl, D.A.X., Voort-van Zijp, N., Pomp, J., Theuws, J., Khalifa, J., Vaart, P. van de, Herk, M. van |
| المصدر: | Radiotherapy and Oncology, 126, 2, pp. 325-332 |
| سنة النشر: | 2018 |
| المجموعة: | Radboud University: DSpace |
| مصطلحات موضوعية: | Radboudumc 9: Rare cancers RIHS: Radboud Institute for Health Sciences |
| الوصف: | Item does not contain fulltext ; PURPOSE: The study compared interobserver variation in the delineation of the primary tumour (GTVp) and lymph nodes (GTVln) between three different 4DCT reconstruction types; Maximum Intensity Projection (MIP), Mid-Ventilation (Mid-V) and Mid-Position (Mid-P). MATERIAL AND METHODS: Seven radiation oncologists delineated the GTVp and GTVln on the MIP, Mid-V and Mid-P 4DCT image reconstructions of 10 lung cancer patients. The volumes, the mean standard deviation (SD) and distribution of SD (SD/area) over the median surface contour were compared for different tumour regions. RESULTS: The overall mean delineated volume on the MIP was significantly larger (p<0.001) than the Mid-V and Mid-P. For the GTVp the Mid-P had the lowest interobserver variation (SD=0.261cm), followed by Mid-V (SD=0.314cm) and MIP (SD=0.330cm) For GTVln the Mid-V had the lowest interobserver variation (SD=0.425cm) followed by the MIP (SD=0.477cm) and Mid-P (SD=0.543cm). The SD/area distribution showed a statistically significant difference between the MIP versus Mid-P and Mid-P versus Mid-V for both GTVp and GTVln (p<0.001), with outliers indicating interpretation differences for GTVp located close to the mediastinum and GTVln. CONCLUSION: The Mid-P reduced the interobserver variation for the GTVp. Delineation protocols must be improved to benefit from the improved image quality of Mid-P for the GTVln. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | http://hdl.handle.net/2066/191324Test |
| DOI: | 10.1016/j.radonc.2017.11.020 |
| الإتاحة: | https://doi.org/10.1016/j.radonc.2017.11.020Test http://hdl.handle.net/2066/191324Test |
| رقم الانضمام: | edsbas.ACE66CBA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.radonc.2017.11.020 |
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