المؤلفون: Balaguer, Francisco de Asís, Mühlethaler, Tobias, Estévez-Gallego, Juan, Calvo, Enrique, Giménez-Abián, Juan F., Risinger, April L., Sorensen, Erik J., Vanderwal, Christopher D., Altmann, Karl-Heinz, Mooberry, Susan, Steinmetz, Michel O., Oliva, María A., Prota, Andrea E., Díaz, José Fernando

المساهمون: Consejo Superior de Investigaciones Científicas (España), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia e Innovación (España), Swiss National Science Foundation, European Commission

مصطلحات موضوعية: Cyclostreptin, Tubulin, Microtubules, Multidrug resistance, Taxanes

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2016-75319-R; Publisher's version; http://dx.doi.org/10.3390/ijms20061392Test; Sí; International Journal of Molecular Sciences 20(6): 1392 (2019); http://hdl.handle.net/10261/178957Test; http://dx.doi.org/10.13039/501100003329Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100003339Test; http://dx.doi.org/10.13039/501100004837Test

الإتاحة: https://doi.org/10.3390/ijms20061392Test
https://doi.org/10.13039/501100003329Test
https://doi.org/10.13039/501100000780Test
https://doi.org/10.13039/501100003339Test
https://doi.org/10.13039/501100004837Test
http://hdl.handle.net/10261/178957Test

المؤلفون: Prota, Andrea E, Lucena-Agell, Daniel, Ma, Yuntao, Estevez-Gallego, Juan, Li, Shuo, Bargsten, Katja, Josa-Prado, Fernando, Altmann, Karl-Heinz, Gaillard, Natacha, Kamimura, Shinji, Mühlethaler, Tobias, Gago, Federico, Oliva, Maria A, Steinmetz, Michel O, Fang, Wei-Shuo, Díaz, J Fernando

الإتاحة: https://doi.org/10.7554/elife.84791.sa2Test

المؤلفون: Mühlethaler, Tobias, Olieric, Natacha, Ehrhard, Valentin A., Wranik, Maximilian, Standfuss, Jörg, Sharma, Ashwani, Prota, Andrea E., Steinmetz, Michel O.

المصدر: Methods in Molecular Biology ; Microtubules ; page 349-374 ; ISSN 1064-3745 1940-6029 ; ISBN 9781071619827 9781071619834

الإتاحة: https://doi.org/10.1007/978-1-0716-1983-4_23Test

المؤلفون: Smedley, Christopher J., Stanley, Paul A., Qazzaz, Mohannad E., Prota, Andrea E., Olieric, Natacha, Collins, Hilary, Eastman, Harry, Barrow, Andrew S., Lim, Kuan-Hon, Kam, Toh-Seok, Smith, Brian J., Duivenvoorden, Hendrika M., Parker, Belinda S., Bradshaw, Tracey D., Steinmetz, Michel O., Moses, John E.

العلاقة: https://nottingham-repository.worktribe.com/output/1408436Test; Scientific Reports; Volume 8; Issue 1; https://nottingham-repository.worktribe.com/file/1408436/1/Jerantinines%20A%20%26%20ETest

الإتاحة: https://doi.org/10.1038/s41598-018-28880-2Test
https://nottingham-repository.worktribe.com/file/1408436/1/Jerantinines%20A%20%26%20ETest
https://nottingham-repository.worktribe.com/output/1408436Test

المؤلفون: Menchon, Grégory, Prota, Andrea E, Lucena-Agell, Daniel, Bucher, Pascal, Jansen, Rolf, Irschik, Herbert, Müller, Rolf, Paterson, Ian, Díaz, J Fernando, Altmann, Karl-Heinz, Steinmetz, Michel O

المساهمون: Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.

المصدر: Nature communications

العلاقة: http://hdl.handle.net/10033/621397Test

الإتاحة: https://doi.org/10.1038/s41467-018-04535-8Test
http://hdl.handle.net/10033/621397Test

المؤلفون: Bueno, Oskía, Estévez-Gallego, Juan, Martins, S., Prota, Andrea E., Gago, Federico, Gómez-SanJuan, Asier, Camarasa Rius, María José, Barasoain, Isabel, Steinmetz, Michel O., Díaz, José Fernando, Peréz-Pérez, María-Jesús, Liekens, Sandra, Priego, Eva María

المساهمون: Ministerio de Economía, Industria y Competitividad (España), Swiss National Science Foundation, European Commission

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2015–64629-C2-1-R; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2015-64629-C2-2-R; info:eu-repo/grantAgreement/EC/H2020/BFU2016-75319-R; Publisher's version; http://dx.doi.org/10.1038/s41598-018-22382-xTest; Sí; e-issn: 2045-2322; Scientific Reports 8: 4242 (2018); http://hdl.handle.net/10261/167786Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100010198Test

الإتاحة: https://doi.org/10.1038/s41598-018-22382-xTest
https://doi.org/10.13039/501100000780Test
https://doi.org/10.13039/501100010198Test
http://hdl.handle.net/10261/167786Test

المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

المصدر: Molecular Cell, vol 68, iss 1

مصطلحات موضوعية: Biological Sciences, Biotechnology, Human Genome, Genetics, Orphan Drug, Cancer, Rare Diseases, Aetiology, Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Antineoplastic Agents, CRISPR-Cas Systems, Colchicine, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Genetic Testing, Genetic Vectors, Glycine, HeLa Cells, Humans, K562 Cells, Kinesins, Lentivirus, Microtubules, Mutation, Myelodysplastic Syndromes, RNA

جغرافية الموضوع: 210 - 223.e6

وصف الملف: application/pdf

العلاقة: qt1d37n4k6; https://escholarship.org/uc/item/1d37n4k6Test

الإتاحة: https://escholarship.org/uc/item/1d37n4k6Test

المؤلفون: Bueno, Oskía, Estévez-Gallego, Juan, Martins, S., Prota, Andrea E., Gago, Federico, Gómez-SanJuan, Asier, Camarasa Rius, María José, Barasoain, Isabel, Steinmetz, Michel O., Díaz, José Fernando, Liekens, Sandra, Peréz-Pérez, María-Jesús, Priego, Eva María

المساهمون: Ministerio de Economía y Competitividad (España), Comunidad de Madrid

مصطلحات موضوعية: Tubulin, Drug design, High affinity, Antitumor activity

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF 2015‐64629‐C2‐1‐R; P2010/BMD‐2457/BIPEDD2; Sí; XVIII Congreso de la Sociedad Española de Química Terapéutica (2018); http://hdl.handle.net/10261/252090Test; http://dx.doi.org/10.13039/100012818Test; http://dx.doi.org/10.13039/501100003329Test

الإتاحة: https://doi.org/10.13039/100012818Test
https://doi.org/10.13039/501100003329Test
http://hdl.handle.net/10261/252090Test

المؤلفون: Trigili, Chiara, Barasoain, Isabel, Sánchez-Murcia, Pedro A., Bargsten, Katja, Redondo-Horcajo, Mariano, Nogales, Aurora, Gardner, Nicola M., Meyer, Arndt, Naylor, Guy J., Gomez-Rubio, Elena, Gago, Federico, Steinmetz, Michel O., Paterson, Ian, Prota, Andrea E., Díaz, José Fernando

المساهمون: Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Swiss National Science Foundation, AstraZeneca

مصطلحات موضوعية: Ligand, Antineoplastic agents, Cells, Noncovalent interactions, Screening assays

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BIO2013-42984-R; http://dx.doi.org/10.1021/acsomega.6b00317Test; Sí; ACS Omega 1(6) 1192- 1204 (2016); http://hdl.handle.net/10261/251270Test; http://dx.doi.org/10.13039/501100003329Test; http://dx.doi.org/10.13039/100004325Test; http://dx.doi.org/10.13039/100012818Test

الإتاحة: https://doi.org/10.1021/acsomega.6b00317Test
https://doi.org/10.13039/501100003329Test
https://doi.org/10.13039/100004325Test
https://doi.org/10.13039/100012818Test
http://hdl.handle.net/10261/251270Test

المؤلفون: Wieczorek, Michal, Tcherkezian, Joseph, Bernier, Cynthia, Prota, Andrea E, Chaaban, Sami, Rolland, Yannève, Godbout, Claude, Hancock, Mark A, Arezzo, Joseph C, Ocal, Ozhan, Rocha, Cecilia, Olieric, Natacha, Hall, Anita, Ding, Hui, Bramoullé, Alexandre, Annis, Matthew G, Zogopoulos, George, Harran, Patrick G, Wilkie, Thomas M, Brekken, Rolf A, Siegel, Peter M, Steinmetz, Michel O, Shore, Gordon C, Brouhard, Gary J, Roulston, Anne

المصدر: Science Translational Medicine, vol 8, iss 365

مصطلحات موضوعية: Neurosciences, Cancer, Neurodegenerative, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Animals, Antineoplastic Agents, Cell Line, Tumor, Crystallography, X-Ray, Dimerization, Genomics, Humans, Lactams, Macrocyclic, Mice, Microscopy, Electron, Microtubules, Mitosis, Neoplasm Transplantation, Neurons, Oxazoles, Tubulin, Vinblastine, Vinca Alkaloids, Vinorelbine, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

العلاقة: qt9dr6h535; https://escholarship.org/uc/item/9dr6h535Test

الإتاحة: https://escholarship.org/uc/item/9dr6h535Test