التفاصيل البيبلوغرافية
العنوان: |
Data_Sheet_1_A randomized trial involving a multifunctional diet reveals systematic lipid remodeling and improvements in cardiometabolic risk factors in middle aged to aged adults.docx |
المؤلفون: |
Claudia Balderas Arroyo, Maider Greño Ocariz, Oksana Rogova, Mahmoud Al-Majdoub, Inger Björck, Juscelino Tovar, Peter Spégel |
سنة النشر: |
2023 |
المجموعة: |
Frontiers: Figshare |
مصطلحات موضوعية: |
Clinical and Sports Nutrition, Dietetics and Nutrigenomics, Nutritional Physiology, Public Nutrition Intervention, Nutrition and Dietetics not elsewhere classified, Food Chemistry and Molecular Gastronomy (excl. Wine), Food Nutritional Balance, Animal Nutrition, Crop and Pasture Nutrition, functional foods, metabolic syndrome, diabetes, cardiovascular disease, degree of unsaturation, carbon number |
الوصف: |
Background A multifunctional diet (MFD) combining foods and ingredients with proven functional properties, such as fatty fish and fiber-rich foods, among others, was developed and shown to markedly reduce cardiometabolic risk-associated factors. Objective Here, we aim at examining metabolic physiological changes associated with these improvements. Methods Adult overweight individuals without other risk factors were enrolled in an 8-week randomized controlled intervention following a parallel design, with one group (n = 23) following MFD and one group (n = 24) adhering to a control diet (CD) that followed the caloric formula (E%) advised by the Nordic Nutritional Recommendations. Plasma metabolites and lipids were profiled by gas chromatography and ultrahigh performance liquid chromatography/mass spectrometry. Results Weight loss was similar between groups. The MFD and CD resulted in altered levels of 137 and 78 metabolites, respectively. Out of these, 83 were uniquely altered by the MFD and only 24 by the CD. The MFD-elicited alterations in lipid levels depended on carbon number and degree of unsaturation. Conclusion An MFD elicits weight loss-independent systematic lipid remodeling, promoting increased circulating levels of long and highly unsaturated lipids. Clinical trial registration https://clinicaltrials.gov/ct2/show/NCT02148653?term=NCT02148653&draw=2&rank=1Test, NCT02148653. |
نوع الوثيقة: |
dataset |
اللغة: |
unknown |
العلاقة: |
https://figshare.com/articles/dataset/Data_Sheet_1_A_randomized_trial_involving_a_multifunctional_diet_reveals_systematic_lipid_remodeling_and_improvements_in_cardiometabolic_risk_factors_in_middle_aged_to_aged_adults_docx/24137010Test |
DOI: |
10.3389/fnut.2023.1236153.s001 |
الإتاحة: |
https://doi.org/10.3389/fnut.2023.1236153.s001Test https://figshare.com/articles/dataset/Data_Sheet_1_A_randomized_trial_involving_a_multifunctional_diet_reveals_systematic_lipid_remodeling_and_improvements_in_cardiometabolic_risk_factors_in_middle_aged_to_aged_adults_docx/24137010Test |
حقوق: |
CC BY 4.0 |
رقم الانضمام: |
edsbas.844A9EE9 |
قاعدة البيانات: |
BASE |