المؤلفون: Sunshine, Sara, Puschnik, Andreas, Replogle, Joseph, Laurie, Matthew, Liu, Jamin, Zha, Beth, Nuñez, James, Byrum, Janie, McMorrow, Aidan, Frieman, Matthew, Winkler, Juliane, Qiu, Xiaojie, Rosenberg, Oren, Leonetti, Manuel, Weissman, Jonathan, DeRisi, Joseph, Hein, Marco, Ye, Chun

المصدر: Nature Communications, vol 14, iss 1

وصف الملف: application/pdf

العلاقة: qt4f4875dd; https://escholarship.org/uc/item/4f4875ddTest

الإتاحة: https://escholarship.org/uc/item/4f4875ddTest

المؤلفون: Baskin, David, Buehler, Jim, Carter, Deirdre, Connelly, Brandon, Cummings, John, Davies, Evelyn, Elliott, John, Etherington, Kelley, Fulton, Brie, Jelinski, John, Kievit, Kenneth, Larson, Jennifer, Malvania, Kushal, Mulholland, Brendan, Nunez, James, Palladino, Carl, Philliber, Jeff, Robertson, Samantha, Saadeh, Joseph, Salvini, Karen, Santos, Bernadette, Sossikian, Leana, Tanouye, Patricia, Xu, Suying

وصف الملف: application/pdf

العلاقة: qt9pv896tj; https://escholarship.org/uc/item/9pv896tjTest

الإتاحة: https://escholarship.org/uc/item/9pv896tjTest

المؤلفون: Samelson, Avi J, Tran, Quang Dinh, Robinot, Rémy, Carrau, Lucia, Rezelj, Veronica V, Kain, Alice Mac, Chen, Merissa, Ramadoss, Gokul N, Guo, Xiaoyan, Lim, Shion A, Lui, Irene, Nuñez, James K, Rockwood, Sarah J, Wang, Jianhui, Liu, Na, Carlson-Stevermer, Jared, Oki, Jennifer, Maures, Travis, Holden, Kevin, Weissman, Jonathan S, Wells, James A, Conklin, Bruce R, TenOever, Benjamin R, Chakrabarti, Lisa A, Vignuzzi, Marco, Tian, Ruilin, Kampmann, Martin

المصدر: Nature Cell Biology, vol 24, iss 1

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Pneumonia, Emerging Infectious Diseases, Cancer, Biodefense, Vaccine Related, Infectious Diseases, Prevention, Lung, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Aetiology, Infection, Good Health and Well Being, Angiotensin-Converting Enzyme 2, Antiviral Agents, COVID-19, Cell Line, Epithelial Cells, Humans, Membrane Glycoproteins, SARS-CoV-2, Transcription Factors, COVID-19 Drug Treatment, Medical and Health Sciences, Developmental Biology

جغرافية الموضوع: 24 - 34

وصف الملف: application/pdf

العلاقة: qt9m5387j8; https://escholarship.org/uc/item/9m5387j8Test

الإتاحة: https://escholarship.org/uc/item/9m5387j8Test

المؤلفون: Baskin, David, Buehler, Jim, Carter, Deirdre, Connelly, Brandon, Cummings, John, Davies, Evelyn, Elliot, John, Etherington, Kelley, Fulton, Brie, Jelinski, John, Kievit, Ken, Larson, Jennifer, Mulholland, Brendan, Nunez, James, Palladino, Carl, Philliber, Jeff, Robertson, Samantha, Saadeh, Joseph, Salvini, Karen, Santos, Bernadette, Sossikian, Leana, Tanouye, Amy, Torkelson, Mike, Xu, Suying

وصف الملف: application/pdf

العلاقة: qt2rb2w57h; https://escholarship.org/uc/item/2rb2w57hTest; https://escholarship.org/content/qt2rb2w57h/qt2rb2w57h.pdfTest

الإتاحة: https://escholarship.org/uc/item/2rb2w57hTest
https://escholarship.org/content/qt2rb2w57h/qt2rb2w57h.pdfTest

المؤلفون: Nuñez, James K, Chen, Jin, Pommier, Greg C, Cogan, J Zachery, Replogle, Joseph M, Adriaens, Carmen, Ramadoss, Gokul N, Shi, Quanming, Hung, King L, Samelson, Avi J, Pogson, Angela N, Kim, James YS, Chung, Amanda, Leonetti, Manuel D, Chang, Howard Y, Kampmann, Martin, Bernstein, Bradley E, Hovestadt, Volker, Gilbert, Luke A, Weissman, Jonathan S

المصدر: Cell, vol 184, iss 9

مصطلحات موضوعية: Biological Sciences, Genetics, Biotechnology, Stem Cell Research - Embryonic - Human, Human Genome, Stem Cell Research, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, CRISPR-Cas Systems, Cell Differentiation, Cellular Reprogramming, CpG Islands, DNA Methylation, Epigenesis, Genetic, Epigenome, Gene Editing, Gene Silencing, Histone Code, Humans, Induced Pluripotent Stem Cells, Neurons, Protein Processing, Post-Translational, CRISPR, cell therapy, dCas9, epigenetics, Medical and Health Sciences

الوقت: 2503 - 2519.e17

وصف الملف: application/pdf

العلاقة: qt4ph8w0v1; https://escholarship.org/uc/item/4ph8w0v1Test

الإتاحة: https://escholarship.org/uc/item/4ph8w0v1Test

المؤلفون: Chen, Jin, Brunner, Andreas-David, Cogan, J Zachery, Nuñez, James K, Fields, Alexander P, Adamson, Britt, Itzhak, Daniel N, Li, Jason Y, Mann, Matthias, Leonetti, Manuel D, Weissman, Jonathan S

المصدر: Science, vol 367, iss 6482

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Prevention, Biodefense, Vaccine Related, Human Genome, Biotechnology, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, CRISPR-Cas Systems, Humans, Open Reading Frames, Operon, Peptides, Protein Biosynthesis, RNA, Messenger, Ribosomes, Transcriptome, General Science & Technology

الوقت: 1140 - 1146

وصف الملف: application/pdf

العلاقة: qt96m1n5z5; https://escholarship.org/uc/item/96m1n5z5Test

الإتاحة: https://escholarship.org/uc/item/96m1n5z5Test

المؤلفون: Adamson, Britt, Norman, Thomas M., Jost, Marco, Cho, Min Y., Nuñez, James K., Chen, Yuwen, Villalta, Jacqueline E., Gilbert, Luke A., Horlbeck, Max A., Hein, Marco Y., Pak, Ryan A., Gray, Andrew N., Gross, Carol A., Parnas, Oren, Weissman, Jonathan S., Dixit, Atray C., Regev, Aviv

المساهمون: Institute for Medical Engineering and Science, Massachusetts Institute of Technology. Department of Biology, Dixit, Atray C., Regev, Aviv

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/J.CELL.2016.11.048Test; Cell; http://hdl.handle.net/1721.1/116762Test; Adamson, Britt et al. “A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.” Cell 167, 7 (December 2016): 1867–1882 © 2016 Elsevier Inc; orcid:0000-0003-2193-9001; orcid:0000-0001-8567-2049

الإتاحة: https://doi.org/10.1016/J.CELL.2016.11.048Test
http://hdl.handle.net/1721.1/116762Test

المؤلفون: Adamson, Britt, Norman, Thomas M, Jost, Marco, Cho, Min Y, Nuñez, James K, Chen, Yuwen, Villalta, Jacqueline E, Gilbert, Luke A, Horlbeck, Max A, Hein, Marco Y, Pak, Ryan A, Gray, Andrew N, Gross, Carol A, Dixit, Atray, Parnas, Oren, Regev, Aviv, Weissman, Jonathan S

المصدر: Cell, vol 167, iss 7

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Human Genome, Vaccine Related, Biotechnology, Underpinning research, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Aetiology, Animals, Clustered Regularly Interspaced Short Palindromic Repeats, Endoribonucleases, Feedback, Humans, Models, Molecular, Protein Serine-Threonine Kinases, RNA, Guide, Kinetoplastida, Sequence Analysis, Single-Cell Analysis, Transcription, Genetic, Unfolded Protein Response, CRIPSRi, CRISPR, Single-cell RNA-seq

الوقت: 1867 - 1882.e21

وصف الملف: application/pdf

العلاقة: qt9961h6m4; https://escholarship.org/uc/item/9961h6m4Test

الإتاحة: https://escholarship.org/uc/item/9961h6m4Test

المؤلفون: Nuñez, James K, Lee, Amy SY, Engelman, Alan, Doudna, Jennifer A

المصدر: Nature, vol 519, iss 7542

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, 1.1 Normal biological development and functioning, Underpinning research, AT Rich Sequence, Adaptive Immunity, CRISPR-Associated Proteins, CRISPR-Cas Systems, Clustered Regularly Interspaced Short Palindromic Repeats, DNA, Superhelical, Escherichia coli, Integrases, Nucleic Acid Conformation, Substrate Specificity, Transposases, General Science & Technology

جغرافية الموضوع: 193 - 198

العلاقة: qt6cd99746; https://escholarship.org/uc/item/6cd99746Test

الإتاحة: https://escholarship.org/uc/item/6cd99746Test

المؤلفون: Nuñez, James K, Harrington, Lucas B, Kranzusch, Philip J, Engelman, Alan N, Doudna, Jennifer A

المصدر: Nature, vol 527, iss 7579

مصطلحات موضوعية: Biological Sciences, Genetics, Adaptive Immunity, Bacteriophage M13, Base Sequence, CRISPR-Associated Proteins, Catalytic Domain, Clustered Regularly Interspaced Short Palindromic Repeats, Crystallography, X-Ray, DNA, Viral, Escherichia coli, Integrases, Models, Molecular, Virus Integration, General Science & Technology

جغرافية الموضوع: 535 - 538

العلاقة: qt618388d8; https://escholarship.org/uc/item/618388d8Test

الإتاحة: https://escholarship.org/uc/item/618388d8Test