دورية أكاديمية
European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of fatty liver disease?
العنوان: | European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of fatty liver disease? |
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المؤلفون: | Lazarus, Jeffrey V., Palayew, Adam, Carrieri, Patrizia, Ekstedt, Mattias, Marchesini, Giulio, Novak, Katja, Ratziu, Vlad, Romero-Gómez, Manuel, Tacke, Frank, Zelber-Sagi, Shira, Cortez-Pinto, Helena, Anstee, Quentin M. |
المساهمون: | EASL International Liver Foundation, Gilead Sciences, Allergan Foundation, Bristol-Myers Squibb, Pfizer, Resoundant, Intercept Pharmaceuticals, Genfit, Ministerio de Ciencia, Innovación y Universidades (España), Instituto de Salud Carlos III, European Commission, Generalitat de Catalunya, NIHR Biomedical Research Centre (UK) |
بيانات النشر: | Elsevier |
سنة النشر: | 2021 |
المجموعة: | Digital.CSIC (Consejo Superior de Investigaciones Científicas / Spanish National Research Council) |
مصطلحات موضوعية: | Non-alcoholic fatty liver disease, Liver health, Multiple joint correspondence analysis, Policy preparedness, Health policy, Metabolic-associated fatty liver disease, Non-alcoholic steatohepatitis, Europe |
الوصف: | [Background & Aims] Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent emerging condition that can be optimally managed through a multidisciplinary patient-centred approach. National preparedness to address NAFLD is essential to ensure that health systems can deliver effective care. We present a NAFLD Preparedness Index for Europe. ; [Methods] In June 2019, data were extracted by expert groups from 29 countries to complete a 41-item questionnaire about NAFLD. Questions were classified into 4 categories: policies/civil society (9 questions), guidelines (16 questions), epidemiology (4 questions), and care management (12 questions). Based on the responses, national preparedness for each indicator was classified into low, middle, or high-levels. We then applied a multiple correspondence analysis to obtain a standardised preparedness score for each country ranging from 0 to 100. ; [Results] The analysis estimated a summary factor that explained 71.3% of the variation in the dataset. No countries were found to have yet attained a high-level of preparedness. Currently, the UK (75.5) scored best, although falling within the mid-level preparedness band, followed by Spain (56.2), and Denmark (43.4), whereas Luxembourg and Ireland were the lowest scoring countries with a score of 4.9. Only Spain scored highly in the epidemiology indicator category, whereas the UK was the only country that scored highly for care management. ; [Conclusions] The NAFLD Preparedness Index indicates substantial variation between countries’ readiness to address NAFLD. Notably, even those countries that score relatively highly exhibit deficiencies in key domains, suggesting that structural changes are needed to optimise NAFLD management and ensure effective public health approaches are in place. ; [Lay summary] Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent ... |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | unknown |
العلاقة: | #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/EC/H2020/634413; info:eu-repo/grantAgreement/EC/H2020/777377; Publisher's version; http://dx.doi.org/10.1016/j.jhepr.2021.100234Test; Sí; e-issn: 2589-5559; other CEX2018-000806-S; JHEP Reports 3(2): 100234 (2021); http://hdl.handle.net/10261/266094Test; http://dx.doi.org/10.13039/100005616Test; http://dx.doi.org/10.13039/100002491Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100002809Test; http://dx.doi.org/10.13039/100005564Test; http://dx.doi.org/10.13039/501100004587Test; http://dx.doi.org/10.13039/100004319Test |
DOI: | 10.1016/j.jhepr.2021.100234 |
DOI: | 10.13039/100005616 |
DOI: | 10.13039/100002491 |
DOI: | 10.13039/501100000780 |
DOI: | 10.13039/501100002809 |
DOI: | 10.13039/100005564 |
DOI: | 10.13039/501100004587 |
DOI: | 10.13039/100004319 |
الإتاحة: | https://doi.org/10.1016/j.jhepr.2021.100234Test https://doi.org/10.13039/100005616Test https://doi.org/10.13039/100002491Test https://doi.org/10.13039/501100000780Test https://doi.org/10.13039/501100002809Test https://doi.org/10.13039/100005564Test https://doi.org/10.13039/501100004587Test https://doi.org/10.13039/100004319Test http://hdl.handle.net/10261/266094Test |
حقوق: | open |
رقم الانضمام: | edsbas.E234C8F9 |
قاعدة البيانات: | BASE |
DOI: | 10.1016/j.jhepr.2021.100234 |
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