التفاصيل البيبلوغرافية
| العنوان: |
The biological clock in cluster headache: A review and hypothesis |
| المؤلفون: |
Naber, Willemijn C, Fronczek, Rolf, Haan, Joost, Doesborg, Patty, Colwell, Christopher S, Ferrari, Michel D, Meijer, Johanna H |
| المصدر: |
Cephalalgia, vol 39, iss 14 |
| بيانات النشر: |
eScholarship, University of California |
| سنة النشر: |
2019 |
| المجموعة: |
University of California: eScholarship |
| مصطلحات موضوعية: |
Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Chronic Pain, Dental/Oral and Craniofacial Disease, Neurodegenerative, Headaches, Pain Research, Sleep Research, Neurological, Biological Clocks, Circadian Rhythm, Cluster Headache, Humans, Circadian, SCN, sleep, light, seasonal, Neurology & Neurosurgery, Biological psychology |
| الوقت: |
1855 - 1866 |
| الوصف: |
ObjectiveTo review and discuss the putative role of light, sleep, and the biological clock in cluster headache.DiscussionCluster headache attacks are believed to be modulated in the hypothalamus; moreover, the severe pain and typical autonomic cranial features associated with cluster headache are caused by abnormal activity of the trigeminal-autonomic reflex. The temporal pattern of cluster headache attacks suggests involvement of the biological clock, and the seasonal pattern is influenced by the number of daylight hours. Although sleep is often reported as a trigger for cluster headache attacks, to date no clear correlation has been established between these attacks and sleep stage.ConclusionsWe hypothesize that light, sleep, and the biological clock can change the brain's state, thereby lowering the threshold for activating the trigeminal-autonomic reflex, resulting in a cluster headache attack. Understanding the mechanisms that contribute to the daily and seasonal fluctuations in cluster headache attacks may provide new therapeutic targets. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| العلاقة: |
qt0tn7r4sh; https://escholarship.org/uc/item/0tn7r4shTest |
| الإتاحة: |
https://escholarship.org/uc/item/0tn7r4shTest |
| حقوق: |
public |
| رقم الانضمام: |
edsbas.3BCC2D1E |
| قاعدة البيانات: |
BASE |
