المؤلفون: Akoto, Theresa, Cai, Jingwen, Nicholas, Sarah, McCord, Hayden, Estes, Amy J., Xu, Hongyan, Karamichos, Dimitrios, Liu, Yutao

المصدر: International Journal of Molecular Sciences

مصطلحات موضوعية: RNA-Sequencing, TGFbeta1 treatment, cornea, cyclic mechanical stretch (CMS), keratoconus (KC), Humans, Keratoconus / metabolism, Transcriptome, Cells, Cultured, Cornea / metabolism, Collagen / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/ijms24087437Test; Akoto, T., Cai, J., Nicholas, S., McCord, H., Estes, A. J., Xu, H., Karamichos, D., & Liu, Y. (2023). Unravelling the Impact of Cyclic Mechanical Stretch in Keratoconus-A Transcriptomic Profiling Study. International journal of molecular sciences, 24(8), 7437. https://doi.org/10.3390/ijms24087437Test; https://hdl.handle.net/20.500.12503/32352Test; 24

الإتاحة: https://doi.org/20.500.12503/32352Test
https://doi.org/10.3390/ijms24087437Test
https://hdl.handle.net/20.500.12503/32352Test

المؤلفون: Karamichos, Dimitrios, Nicholas, Sarah E., Khan, Asher, Riaz, Kamran M.

المصدر: Biomolecules

مصطلحات موضوعية: 3D self-assembled ECM model, Wnt signaling, c-Src kinase, collagen crosslinking, corneal fibrosis, cyclin D1, keratoconus, peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PCG-1), primary corneal stromal fibroblast, prolactin-induced protein (PIP), Humans, Keratoconus / drug therapy, Keratoconus / metabolism, Cornea / metabolism, Collagen / metabolism, Corneal Stroma / metabolism, Extracellular Matrix / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/biom13040696Test; Karamichos, D., Nicholas, S. E., Khan, A., & Riaz, K. M. (2023). Collagen Crosslinking for Keratoconus: Cellular Signaling Mechanisms. Biomolecules, 13(4), 696. https://doi.org/10.3390/biom13040696Test; https://hdl.handle.net/20.500.12503/32363Test; 13

الإتاحة: https://doi.org/20.500.12503/32363Test
https://doi.org/10.3390/biom13040696Test
https://hdl.handle.net/20.500.12503/32363Test

المؤلفون: Liang, Wentao, Huang, Li, Whelchel, Amy E., Yuan, Tian, Ma, Xiang, Cheng, Rui, Takahashi, Yusuke, Karamichos, Dimitrios, Ma, Jian-Xing

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: PPARalpha, cornea, epithelium, mitochondria, wound healing, Mice, Humans, Animals, PPAR alpha / genetics, PPAR alpha / metabolism, Diabetes Mellitus, Experimental / genetics, Experimental / metabolism, Cornea / metabolism, Wound Healing / physiology, Knockout, Mitochondria / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1073/pnas.2217576120Test; Liang, W., Huang, L., Whelchel, A., Yuan, T., Ma, X., Cheng, R., Takahashi, Y., Karamichos, D., & Ma, J. X. (2023). Peroxisome proliferator-activated receptor-α (PPARα) regulates wound healing and mitochondrial metabolism in the cornea. Proceedings of the National Academy of Sciences of the United States of America, 120(13), e2217576120. https://doi.org/10.1073/pnas.2217576120Test; https://hdl.handle.net/20.500.12503/32338Test; 120; 13

الإتاحة: https://doi.org/20.500.12503/32338Test
https://doi.org/10.1073/pnas.2217576120Test
https://hdl.handle.net/20.500.12503/32338Test

المؤلفون: McKay, Tina B., Priyadarsini, Shrestha, Rowsey, Tyler, Karamichos, Dimitrios

المصدر: Cells

مصطلحات موضوعية: arginine, collagen, cornea, extracellular matrix, hydroxyproline, keratoconus, metabolomics, tissue-engineered cornea, Arginase / metabolism, Arginine / metabolism, Arginine / pharmacology, Arginine / therapeutic use, Case-Control Studies, Cell Culture Techniques, Cells, Cultured, Collagen / metabolism, Collagen Type I / metabolism, Cornea / cytology, Cornea / metabolism, Extracellular Matrix / metabolism, Fibroblasts / cytology, Fibroblasts / drug effects, Fibroblasts / metabolism, Humans, Keratoconus / drug therapy, Keratoconus / metabolism, Keratoconus / pathology, Nitric Oxide Synthase / metabolism, Ornithine / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/cells10082076Test; McKay, T. B., Priyadarsini, S., Rowsey, T., & Karamichos, D. (2021). Arginine Supplementation Promotes Extracellular Matrix and Metabolic Changes in Keratoconus. Cells, 10(8), 2076. https://doi.org/10.3390/cells10082076Test; https://hdl.handle.net/20.500.12503/31787Test; 10

الإتاحة: https://doi.org/20.500.12503/31787Test
https://doi.org/10.3390/cells10082076Test
https://hdl.handle.net/20.500.12503/31787Test

المؤلفون: McKay, Tina B., Priyadarsini, Shrestha, Karamichos, Dimitrios

المصدر: Cells

مصطلحات موضوعية: cornea, estradiol, estrogen, growth hormone, insulin growth factor-1, wound healing, Animals, Cornea / metabolism, Gonadal Steroid Hormones / chemistry, Gonadal Steroid Hormones / metabolism, Growth Hormone / metabolism, Humans, Receptors, Cell Surface / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/cells11020224Test; McKay, T. B., Priyadarsini, S., & Karamichos, D. (2022). Sex Hormones, Growth Hormone, and the Cornea. Cells, 11(2), 224. https://doi.org/10.3390/cells11020224Test; https://hdl.handle.net/20.500.12503/31795Test; 11

الإتاحة: https://doi.org/20.500.12503/31795Test
https://doi.org/10.3390/cells11020224Test
https://hdl.handle.net/20.500.12503/31795Test

المؤلفون: Escandon, Paulina, Liu, Angela, Nicholas, Sarah E., Khan, Asher, Riaz, Kamran M., Karamichos, Dimitrios

المصدر: International Journal of Molecular Sciences

مصطلحات موضوعية: cell migration, corneal wound healing, diabetes mellitus, fibrosis, keratoconus, ocular diseases, salivary exosomes, Cell Movement, Cornea / metabolism, Corneal Injuries / metabolism, Exosomes, Humans, Stromal Cells, Wound Healing

وصف الملف: application/pdf

العلاقة: https://doi.org/10.3390/ijms23084330Test; Escandon, P., Liu, A., Nicholas, S. E., Khan, A., Riaz, K. M., & Karamichos, D. (2022). Unravelling Novel Roles of Salivary Exosomes in the Regulation of Human Corneal Stromal Cell Migration and Wound Healing. International journal of molecular sciences, 23(8), 4330. https://doi.org/10.3390/ijms23084330Test; https://hdl.handle.net/20.500.12503/31797Test; 23

الإتاحة: https://doi.org/20.500.12503/31797Test
https://doi.org/10.3390/ijms23084330Test
https://hdl.handle.net/20.500.12503/31797Test

المساهمون: College of Medicine, Dept. of Ophthalmology, Seung-il Choi, Eunhee Lee, Jang Bin Jeong, Begum Akuzum, Yong-Sun Maeng, Tae-im Kim, Eung Kweon Kim, Kim, Eung Kweon, Kim, Tae Im, Choi, Seung Il, Maeng, Yong Sun

مصطلحات موضوعية: Apoptosis/drug effects, Cells, Cultured, Cornea/drug effects, Cornea/metabolism, Cornea/physiopathology, Corneal Dystrophies, Hereditary/drug therapy, Hereditary/pathology, Hereditary/physiopathology, Dose-Response Relationship, Drug, Down-Regulation/drug effects, Endoplasmic Reticulum Stress/drug effects, Endoplasmic Reticulum-Associated Degradation/drug effects, Extracellular Matrix Proteins/genetics, Extracellular Matrix Proteins/metabolism, Fibroblasts/drug effects, Fibroblasts/metabolism, Fibroblasts/pathology, Humans, Mutation/drug effects, Mutation/genetics, Phenylbutyrates/administration & dosage, Transforming Growth Factor beta/genetics, Transforming Growth Factor beta/metabolism, 4-Phenylbutyric acid, Corneal fibroblasts, ER stress, ERAD

العلاقة: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; J00281; OAK-2016-04619; https://ir.ymlib.yonsei.ac.kr/handle/22282913/151868Test; http://www.sciencedirect.com/science/article/pii/S0006291X16310737Test; T201602956; BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.477(4) : 841-846, 2016

الإتاحة: https://doi.org/10.1016/j.bbrc.2016.06.146Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151868Test
http://www.sciencedirect.com/science/article/pii/S0006291X16310737Test

المساهمون: College of Medicine, Dept. of Ophthalmology, Seung-il Choi, Jun-Yup Jin, Yong-Sun Maeng, Tae-im Kim, Eung Kweon Kim, Kim, Eung Kweon, Kim, Tae Im, Maeng, Yong Sun, Choi, Seung Il

مصطلحات موضوعية: Cells, Cultured, Cornea/cytology, Cornea/metabolism, Corneal Dystrophies, Hereditary/genetics, Hereditary/metabolism, Hereditary/pathology, Extracellular Matrix Proteins/genetics, Extracellular Matrix Proteins/metabolism, Fibroblasts/cytology, Fibroblasts/metabolism, Gene Expression Regulation, Homozygote, Humans, MicroRNAs/genetics, MicroRNAs/metabolism, Models, Biological, Mutant Proteins/genetics, Mutant Proteins/metabolism, Point Mutation, RNA, Messenger/genetics, Messenger/metabolism, Signal Transduction, Smad Proteins/metabolism, Transforming Growth Factor beta/genetics, Transforming Growth Factor beta/metabolism, Transforming Growth Factor beta1/metabolism

وصف الملف: 150~155

العلاقة: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; J00281; OAK-2016-01111; https://ir.ymlib.yonsei.ac.kr/handle/22282913/146486Test; http://www.sciencedirect.com/science/article/pii/S0006291X16302753Test; T201600680; BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.472(1) : 150-155, 2016

الإتاحة: https://doi.org/10.1016/j.bbrc.2016.02.086Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146486Test
http://www.sciencedirect.com/science/article/pii/S0006291X16302753Test

المساهمون: Yuri Seo, Mee Kum Kim, Joon H. Lee, Eun-Ju Chang, Eung Kweon Kim, Hyung Keun Lee, Kim, Eung Kweon, Lee, Hyung Keun

مصطلحات موضوعية: Adult, Aged, Biomarkers/metabolism, Cornea/metabolism, Cornea/pathology, Female, Gene Expression Regulation, Graft Rejection/genetics, Graft Rejection/metabolism, Graft Rejection/pathology, Humans, Keratoplasty, Penetrating/adverse effects, Lymphangiogenesis/genetics, Male, Microscopy, Confocal, Middle Aged, RNA/genetics, Real-Time Polymerase Chain Reaction, Vascular Endothelial Growth Factors/biosynthesis, Vascular Endothelial Growth Factors/genetics, Young Adult, Lymphangiogenesis, VEGF, VEGFR, penetrating keratoplasty, rejection

وصف الملف: 902~912

العلاقة: CURRENT EYE RESEARCH; J00665; OAK-2015-00009; https://ir.ymlib.yonsei.ac.kr/handle/22282913/139169Test; T201406216; CURRENT EYE RESEARCH, Vol.40(9) : 902-912, 2015

الإتاحة: https://doi.org/10.3109/02713683.2014.969809Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139169Test

المساهمون: Yong Woo Ji, Yuri Seo, Wungrak Choi, Areum Yeo, Hyemi Noh, Eung Kweon Kim, Hyung Keun Lee, Kim, Eung Kweon, Noh, Hae Mi, Yeo, Areum, Lee, Hyung Keun

مصطلحات موضوعية: Animals, CD11b Antigen/immunology, Cell Proliferation, Cornea/metabolism, Cornea/pathology, Cyclooxygenase 2/genetics, Cyclooxygenase 2/metabolism, Disease Models, Animal, Dry Eye Syndromes/genetics, Dry Eye Syndromes/immunology, Dry Eye Syndromes/metabolism, Female, Flow Cytometry, Gene Expression Regulation, Immunohistochemistry, Lymph Nodes/immunology, Lymph Nodes/metabolism, Mice, Inbred C57BL, RNA, Messenger/genetics, Real-Time Polymerase Chain Reaction, Receptors, CCR7/immunology, CCR7/metabolism, Lymphocyte Homing/immunology, Lymphocyte Homing/metabolism, EP receptor, chemokine receptor CCR7

العلاقة: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE; J01187; OAK-2014-02848; https://ir.ymlib.yonsei.ac.kr/handle/22282913/138581Test; http://iovs.arvojournals.org/article.aspx?articleid=2212604Test; T201404881; INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol.55(10) : 6829-6838, 2014; 38418

الإتاحة: https://doi.org/10.1167/iovs.14-14744Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/138581Test
http://iovs.arvojournals.org/article.aspx?articleid=2212604Test