صورة
Lumbar Chordoma: A Primary Bone Tumor
| العنوان: | Lumbar Chordoma: A Primary Bone Tumor |
|---|---|
| المؤلفون: | Fleischman, BS, Andrew N., O'Hara, MD, Brian |
| المصدر: | Department of Pathology Honors Program Student Research Symposium |
| بيانات النشر: | Jefferson Digital Commons |
| سنة النشر: | 2013 |
| المجموعة: | Jefferson Digital Commons (Thomas Jefferson University, Philadelphia) |
| مصطلحات موضوعية: | Lumbar Chordoma: A Primary Bone Tumor, poster, 15th annual pathology honors program student research symposium, Thomas Jefferson University, Pathology |
| الوصف: | INTRODUCTION Primary malignant bone tumor of embryonic notochord remnants 1-4% of primary bone tumors, <0.1 per 100,000 Location: Sacral (50%), Skull base (35%), Vertebral column (15%) Classic, chondroid (5-15%), and dedifferentiated (5%) variants Most commonly in late middle age (50s to 60s) Low-grade, slow growing tumor But locally aggressive, high rate of local recurrence (20% in 1st year) Local recurrence is most important predictor of mortality Metastasis only occurs very late in disease Median survival of about 6 years, less than 12 months with mets 5 year survival of 70%, 10 year survival of 40% Primary therapy- aggressive surgical resection (if possible) New targeted therapies currently under investigation |
| نوع الوثيقة: | still image |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://jdc.jefferson.edu/phsrs/3Test; https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1002&context=phsrsTest |
| الإتاحة: | https://jdc.jefferson.edu/phsrs/3Test https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1002&context=phsrsTest |
| رقم الانضمام: | edsbas.600145D7 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |