التفاصيل البيبلوغرافية
| العنوان: |
GATE retrotransposon in Drosophila melanogaster: mobility in heterochromatin and aspects of its expression in germline tissues |
| المؤلفون: |
Kogan, G. L., Tulin, A. V., Aravin, A. A., Abramov, Yu. A., Kalmykova, A. I., Maisonhaute, C., Gvozdev, V. A. |
| المصدر: |
Molecular Genetics and Genomics, 269(2), 234-242, (2003-05) |
| بيانات النشر: |
Springer Nature |
| سنة النشر: |
2003 |
| المجموعة: |
Caltech Authors (California Institute of Technology) |
| مصطلحات موضوعية: |
Drosophila melanogaster, Retrotransposon, Heterochromatin, RNA interference |
| الوصف: |
A full-length copy of the retrotransposon GATE was identified as an insertion in the tandemly repeated, heterochromatic, Stellate genes, which are expressed in the testis of Drosophila melanogaster. Sequencing of this heterochromatic GATE copy revealed that it is closely related to the BEL retrotransposon, a representative of the recently defined BEL -like group of LTR retrotransposons. This copy contains identical LTRs, indicating that the insertion is a recent event. By contrast, the euchromatic part of the D. melanogaster genome contains only profoundly damaged GATE copies or fragments of the transposon. The preferential localization of GATE sequences in heterochromatin was confirmed for the other species in themelanogaster subgroup. The level of GATE expression is dramatically increased in ovaries, but not in testes, of spn-E^1 homozygous flies. We speculate that spn-E is involved in the silencing of GATE via an RNA interference mechanism. ; © 2003 Springer-Verlag. Received: 15 October 2002; Accepted: 27 January 2003; Published online: 14 March 2003. We are grateful to M. B. Evgen'ev and B. D. McKee for the gifts of various species of flies. This work was supported by grants from the Russian Foundation for Basic Research (N 00-15-97896, 01-04-22001, 01-04-48514, 02-04-48498, and PICS N1191). |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
https://doi.org/10.1007/s00438-003-0827-1Test; oai:authors.library.caltech.edu:km785-wzr59; eprintid:95416; resolverid:CaltechAUTHORS:20190513-074617352 |
| DOI: |
10.1007/s00438-003-0827-1 |
| الإتاحة: |
https://doi.org/10.1007/s00438-003-0827-1Test |
| حقوق: |
info:eu-repo/semantics/closedAccess ; Other |
| رقم الانضمام: |
edsbas.26F13B4B |
| قاعدة البيانات: |
BASE |
