دورية أكاديمية

Patterns of attention deficit hyperactivity disorder medicine use in the era of new non-stimulant medicines: A population-based study among Australian children and adults (2013–2020)

التفاصيل البيبلوغرافية
العنوان: Patterns of attention deficit hyperactivity disorder medicine use in the era of new non-stimulant medicines: A population-based study among Australian children and adults (2013–2020)
المؤلفون: Bruno, C, Havard, A, Gillies, MB, Coghill, D, Brett, J, Guastella, AJ, Pearson, SA, Zoega, H
المصدر: urn:ISSN:0004-8674 ; urn:ISSN:1440-1614 ; Australian and New Zealand Journal of Psychiatry, 57, 5, 675-685
بيانات النشر: SAGE
سنة النشر: 2023
المجموعة: UNSW Sydney (The University of New South Wales): UNSWorks
مصطلحات موضوعية: Pediatric, Mental Health, Attention Deficit Hyperactivity Disorder (ADHD), 6 Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, 3 Good Health and Well Being, Male, Adolescent, Female, Young Adult, Humans, Child, Preschool, Attention Deficit Disorder with Hyperactivity, Guanfacine, Transition to Adult Care, Australia, Central Nervous System Stimulants, Attention deficit hyperactivity disorder, drug utilisation, anzsrc-for: 11 Medical and Health Sciences, anzsrc-for: 17 Psychology and Cognitive Sciences
الوصف: Background and aims: New therapeutic options such as lisdexamfetamine and guanfacine have recently become available for the treatment of attention deficit hyperactivity disorder. We described contemporary patterns of attention deficit hyperactivity disorder medicine use among children, adolescents and adults in Australia. Methods: This population-based study used dispensing data for a 10% random sample of Australian residents between July 2012 and December 2020. We estimated the annual prevalence and incidence of attention deficit hyperactivity disorder medicines, second-line guanfacine use and examined concurrent medicine use of both stimulants and non-stimulants. We followed incident users for up to 5 years and analysed treatment persistence using a novel proportion of people covered method. Analyses were stratified by attention deficit hyperactivity disorder medicine, sex and age group; young children (0–5 years), children (6–12 years), adolescents (13–17 years), young adults (18–24 years) and adults (⩾25 years). Results: We observed a twofold increase in the overall prevalence of attention deficit hyperactivity disorder medicine use between 2013 and 2020, from 4.9 to 9.7 per 1000 persons. Incident use also increased across all age groups and both sexes, with the most pronounced increases among adolescent females (from 1.4 to 5.3 per 1000 persons). Stimulant treatment persistence after 5 years was highest among those initiating treatment as young children (64%) and children (69%) and lowest among those initiating treatment in adolescence (19%). Concurrent use of stimulants and non-stimulants was more common among males and younger age groups. Most children (87%) initiating guanfacine had prior dispensings of attention deficit hyperactivity disorder medicines. Conclusion: We observed increasing attention deficit hyperactivity disorder medicine use in Australia, especially among young females. Nevertheless, treatment rates remain lower than the estimated prevalence of attention deficit hyperactivity disorder ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: unknown
العلاقة: http://hdl.handle.net/1959.4/unsworks_81597Test; https://unsworks.unsw.edu.au/bitstreams/65a56833-f55e-411b-8c24-58fae7316b30/downloadTest; https://doi.org/10.1177/00048674221114782Test
DOI: 10.1177/00048674221114782
الإتاحة: https://doi.org/10.1177/00048674221114782Test
http://hdl.handle.net/1959.4/unsworks_81597Test
https://unsworks.unsw.edu.au/bitstreams/65a56833-f55e-411b-8c24-58fae7316b30/downloadTest
حقوق: open access ; https://purl.org/coar/access_right/c_abf2Test ; CC-BY ; https://creativecommons.org/licenses/by/4.0Test/ ; free_to_read
رقم الانضمام: edsbas.729AFB9
قاعدة البيانات: BASE