دورية أكاديمية
Examination of the Effects on Orexin A on Rodentive Appetitive and Consumatory Behaviors Using a Progressive Ratio Schedule of Reinforcement
| العنوان: | Examination of the Effects on Orexin A on Rodentive Appetitive and Consumatory Behaviors Using a Progressive Ratio Schedule of Reinforcement |
|---|---|
| المؤلفون: | Nguyen, Tuong-Vi (Madeline) |
| المصدر: | Psychology Honors Projects |
| بيانات النشر: | DigitalCommons@Macalester College |
| سنة النشر: | 2007 |
| المجموعة: | Macalester College (Minnesota): DigitalCommons@Macalester |
| مصطلحات موضوعية: | orexin, rats, behaviors |
| الوصف: | Orexin has important functions in feeding, arousal, and motivation. However, the mechanism by which Orexin influences these processes is not well understood. The goals of the present study were: 1) demonstrate that orexin A enhances appetitive and consumptive behaviors (lever presses, licks, rewarded licks and breakpoint) using a progressive ratio schedule of reinforcement for sucrose reward and 2) Determine if gamma-aminobutyric acid receptor blockade could attenuate those behaviors. However, preliminary analysis did not reveal an effect of orexin A (30nM) when infused into the lateral ventricle of rats. Of the measures operant behaviors, the orexin A and saline groups did not differ. Therefore, the second phase was not conducted. Multiple explanations for the lack of orexin's effect are possible: aged rats, endogenous orexin levels, incorrect dose, misplaced cannula and use of a different schedule of reinforcement than that previously used with orexin. The unique function of orexin in these behaviors prompts further analysis into the reason behind the outcomes of this study. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://digitalcommons.macalester.edu/psychology_honors/6Test; https://digitalcommons.macalester.edu/context/psychology_honors/article/1005/viewcontent/Nguyen3.pdfTest |
| الإتاحة: | https://digitalcommons.macalester.edu/psychology_honors/6Test https://digitalcommons.macalester.edu/context/psychology_honors/article/1005/viewcontent/Nguyen3.pdfTest |
| رقم الانضمام: | edsbas.1D776467 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |