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1Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease
المؤلفون: Ying Sun, Wenyu Fu, Aubryanna Hettinghouse, Jinlong Jian, Rossella Liberti, Xiangli Zhao, Chuan-ju Liu
المصدر: J Mol Med (Berl)
مصطلحات موضوعية: Mice, Knockout, Gaucher Disease, Ovalbumin, Chemistry, Autophagy, Autophagosomes, Regulator, Context (language use), Disease, Allergens, Molecular medicine, Article, Cell biology, rab2 GTP-Binding Protein, Progranulins, Animal model, Mediator, Drug Discovery, Autophagosome lysosome fusion, Animals, Humans, Molecular Medicine, Lysosomes, Cells, Cultured, Genetics (clinical)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b709c49fee238e518915444ce3ca063Test
https://doi.org/10.1007/s00109-021-02127-6Test -
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المؤلفون: Seiya Oura, Haruhiko Miyata, Akane Morohoshi, Masahito Ikawa, Yuki Oyama, Taichi Noda
المصدر: Development (Cambridge, England)
article-version (VoR) Version of Recordمصطلحات موضوعية: Male, Mouse, Immunoprecipitation, Golgi Apparatus, Mice, Transgenic, Biology, Mice, Teratozoospermia, Testis, Organelle, Genetics, medicine, Animals, Small GTPase, Spermatogenesis, Acrosome, Molecular Biology, Infertility, Male, Reproductive Biology, Spermatid, Vesicle, Nuclear Proteins, Cell biology, Vesicular transport protein, rab2 GTP-Binding Protein, Fertility, medicine.anatomical_structure, rab GTP-Binding Proteins, Sperm Head, Globozoospermia, Biogenesis, Protein Binding, Research Article, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d85b590059b66c7d02ed1ec97ff3d6Test
https://doi.org/10.1242/dev.199644Test -
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المؤلفون: Christine Quentin, Veronika Lysiuk, Stephan J. Sigrist, Alexander G. Nikonenko, Martin Lehmann, Astrid G. Petzoldt, Torsten W.B. Götz, Janine Lützkendorf, Dmytro Puchkov
المصدر: The Journal of Cell Biology
مصطلحات موضوعية: Male, Vesicular Glutamate Transport Proteins, Synaptogenesis, Presynaptic Terminals, Golgi Apparatus, Nerve Tissue Proteins, Neurotransmission, Biology, Synaptic vesicle, Synaptic Transmission, Article, symbols.namesake, Lysosomal-Associated Membrane Protein 1, Animals, Small GTPase, Active zone, Neurons, Trafficking, Vesicle, Membrane Proteins, Cell Biology, Golgi apparatus, Axons, Cell biology, Protein Transport, rab2 GTP-Binding Protein, Drosophila melanogaster, symbols, Female, Synaptic Vesicles, Lysosomes, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b605c57c71aadbaed20270488e3a9b12Test
https://pubmed.ncbi.nlm.nih.gov/33822845Test -
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المؤلفون: Ulrik Gether, Anders Schack, Matthew D. Lycas, Ole Kjaerulff, Viktor K. Lund, Rita C. Andersen
المصدر: Lund, V K, Lycas, M D, Schack, A, Andersen, R C, Gether, U & Kjaerulff, O 2021, ' Rab2 drives axonal transport of dense core vesicles and lysosomal organelles ', Cell Reports, vol. 35, no. 2, 108973 . https://doi.org/10.1016/j.celrep.2021.108973Test
Cell Reports, Vol 35, Iss 2, Pp 108973-(2021)مصطلحات موضوعية: 0301 basic medicine, Monosaccharide Transport Proteins, QH301-705.5, Endosome, Synaptogenesis, Motility, Endosomes, GTPase, Axonal Transport, Membrane Fusion, General Biochemistry, Genetics and Molecular Biology, Rab2, 03 medical and health sciences, 0302 clinical medicine, lysosomes, Organelle, Arl8, Molecular motor, Animals, Drosophila Proteins, Lectins, C-Type, Small GTPase, Biology (General), Neurons, Organelle Biogenesis, synaptogenesis, ADP-Ribosylation Factors, Chemistry, membrane trafficking, neuropeptides, Dense Core Vesicles, Cell biology, rab2 GTP-Binding Protein, Drosophila melanogaster, 030104 developmental biology, Gene Expression Regulation, endosomes, Multiprotein Complexes, Axoplasmic transport, Drosophila, axonal transport, Lysosomes, dense core vesicles, 030217 neurology & neurosurgery, Biogenesis, Protein Binding, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215da4125209d671a0ba2e59d966d926Test
https://doi.org/10.1101/2020.06.03.131672Test -
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المؤلفون: Peipei Gao, Ting Peng, Yifan Meng, Ping Wu, Canhui Cao, Wenhua Zhi, Peng Wu, Shitong Lin, Lingli Gui
المصدر: Bioscience Reports
مصطلحات موضوعية: 0301 basic medicine, Bioinformatics, Biophysics, Breast Neoplasms, Genomics, GTPase, Biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Databases, Genetic, Biomarkers, Tumor, medicine, Humans, Genetic Predisposition to Disease, Neoplasm Invasiveness, Protein Interaction Maps, Molecular Biology, Gene, Diagnostics & Biomarkers, Research Articles, Survival analysis, Cancer, Messenger RNA, Gene Expression & Regulation, Biologic biomarkers, Gene Expression Profiling, Computational Biology, Cell Biology, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, rab1 GTP-Binding Proteins, Gene expression profiling, rab2 GTP-Binding Protein, Phenotype, 030104 developmental biology, rab GTP-Binding Proteins, 030220 oncology & carcinogenesis, Cancer research, Female, RAB family genes, Rab, Transcriptome, Breast invasive carcinoma
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cce9aad982a3e0e86dafd7e47d0f45eTest
https://doi.org/10.1042/bsr20201103Test -
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المؤلفون: Erin P, Smith, Alexis, Cotto-Rosario, Elizabeth, Borghesan, Kiara, Held, Cheryl N, Miller, Jean, Celli
المصدر: mBio
مصطلحات موضوعية: epistasis, Macrophages, pathogenesis, Golgi Apparatus, Epistasis, Genetic, Gene Expression Regulation, Bacterial, macrophage, Endoplasmic Reticulum, Brucella, type IV secretion, Brucellosis, Host-Microbe Biology, Type IV Secretion Systems, Rab2, Protein Transport, rab2 GTP-Binding Protein, Host-Pathogen Interactions, Protein Binding, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::9c7f7d0f49db8da70dc7178a3d3ec15dTest
https://pubmed.ncbi.nlm.nih.gov/32234817Test -
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المؤلفون: Tatsuya Kozaki, Takuma Misawa, Mitsunori Fukuda, Norihiko Ohbayashi, Michihiro Takahama, Shizuo Akira, Toru Okamoto, Yoshiharu Matsuura, Tatsuya Saitoh
المصدر: Cell Reports, Vol 20, Iss 12, Pp 2944-2954 (2017)
مصطلحات موضوعية: 0301 basic medicine, organelle, Guanosine triphosphate, antiviral response, Mice, chemistry.chemical_compound, Cytosol, Interferon, Phosphorylation, innate immunity, lcsh:QH301-705.5, Effector, Intracellular Signaling Peptides and Proteins, interferon, Nucleotidyltransferases, Cell biology, Protein Transport, host defense, Stimulator of interferon genes, symbols, Guanosine Triphosphate, Signal transduction, Signal Transduction, medicine.drug, Vaccinia virus, Biology, Antiviral Agents, Article, General Biochemistry, Genetics and Molecular Biology, Virus, 03 medical and health sciences, symbols.namesake, medicine, Animals, Humans, Monomeric GTP-Binding Proteins, Membrane Proteins, DNA, Fibroblasts, Golgi apparatus, Embryo, Mammalian, Immunity, Innate, rab2 GTP-Binding Protein, HEK293 Cells, 030104 developmental biology, lcsh:Biology (General), chemistry, Interferon Regulatory Factor-3, Rab GTPase
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69855ae908bc7b96d1d37d7e5d2a278Test
https://doi.org/10.1016/j.celrep.2017.08.085Test -
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المؤلفون: Iuliana Ionita-Laza, Bin Xu, Maria Karayiorgou, Atsushi Takata, Joseph A. Gogos
المصدر: Neuron. 89(5):940-947
مصطلحات موضوعية: 0301 basic medicine, Male, Databases, Factual, Neuroscience(all), Nerve Tissue Proteins, Disease, Biology, medicine.disease_cause, Article, Machine Learning, 03 medical and health sciences, mental disorders, medicine, Humans, Exome, Genetic Predisposition to Disease, Regulatory Elements, Transcriptional, Autistic Disorder, Gene, Genetic Association Studies, Genetics, Mutation, General Neuroscience, Rab2 GTP-Binding Protein, Histone-Lysine N-Methyltransferase, Sequence Analysis, DNA, medicine.disease, MicroRNAs, rab2 GTP-Binding Protein, 030104 developmental biology, Schizophrenia, Autism, Female, Synonymous substitution
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5131dae9eef956b95724aba6203d9075Test
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المؤلفون: Shufeng Zhang, Ying Sun, Linchao Zhu, Lin Wang
المصدر: Molecular and cellular biochemistry. 466(1-2)
مصطلحات موضوعية: 0301 basic medicine, Carcinoma, Hepatocellular, MAP Kinase Signaling System, Clinical Biochemistry, medicine.disease_cause, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Gentamicin protection assay, medicine, PTEN, Humans, MTT assay, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Mitogen-Activated Protein Kinase 1, Gene knockdown, Mitogen-Activated Protein Kinase 3, biology, Oncogene, Chemistry, Liver Neoplasms, PTEN Phosphohydrolase, Cell Biology, General Medicine, Hep G2 Cells, digestive system diseases, rab2 GTP-Binding Protein, 030104 developmental biology, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, biology.protein, Cancer research, Carcinogenesis, Proto-Oncogene Proteins c-akt
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350f19241759fff41b31cb323e0b981fTest
https://pubmed.ncbi.nlm.nih.gov/32052247Test -
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المؤلفون: Qiming Sun, Xinyi Wang, Mei Mei, She Chen, Yushan Zhu, Shilai Bao, Rui Tian, Xiao Jiang, Pengwei Zhao, Wei Liu, Lin Li, Zaiming Tang, Xianming Ding
المصدر: Autophagy
مصطلحات موضوعية: 0301 basic medicine, Autophagosome, Male, GOLGA2, Autolysosome, Biology, RAB2, 03 medical and health sciences, symbols.namesake, Mice, Sequestosome 1, Autophagy, Animals, Humans, RUBCNL, education, Molecular Biology, ATG16L1, Cells, Cultured, Mammals, Mice, Knockout, education.field_of_study, 030102 biochemistry & molecular biology, Autophagosomes, Cell Biology, BECN1, Golgi apparatus, autolysosome, Cell biology, Mice, Inbred C57BL, rab2 GTP-Binding Protein, 030104 developmental biology, Eukaryotic Cells, HEK293 Cells, symbols, Lysosomes, RAB11A, HeLa Cells, Research Paper
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5462057d608ee6a9377e72beec5781aTest
https://pubmed.ncbi.nlm.nih.gov/30957628Test