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المؤلفون: Giambelluca, Sonia, Ochs, Matthias, Lopez-Rodriguez, Elena
المصدر: Frontiers in immunology. 13
مصطلحات موضوعية: cell differentiation, interleukin-beta (IL-1beta), model, ASC speck, pro-caspase-1, macrophage surface markers, monocyte-macrophage, in vitro, phorbol 12-myristate 13-acetate (PMA), 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31475183094c7e95dde9309eb16fef5Test
https://pubmed.ncbi.nlm.nih.gov/36618426Test -
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المؤلفون: Chuyao Liao, Di Wang, Ying Zhang, Zunjian Zhang, Fengguo Xu, Siyuan Qin, Yuxin Zhang, Danting Li, Yuan Tian, Jie Chen
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 763-780 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: CYP1A1, cytochrome P450 1A1, PF, PF-04859989, MOE, molecular operating environment, MTT, thiazolyl blue tetrazolium bromide, Kynurenine pathway, RPKM, reads per kilobase per million mapped reads, STAT3, signal transducer and activator of transcription 3, KAT, kynurenine aminotransferase, AHR, GPR35, G protein-coupled receptor 35, HRP, horseradish peroxi-dase, KA, kynurenic acid, RIPA, radioimmunoprecipitation, DMSO, dimethyl sulfoxide, ECL, enhanced chemiluminescence, Pharmacology, DPP-4, dipeptidyl peptidase-4, PDE5, phosphodiesterase type-5, RT-PCR, real-time polymerase chain reaction, CPT-11, irinotecan, AHR, aryl hydrocarbon receptor, chemistry.chemical_compound, DSS, dextran sulphate sodium, Intestinal toxicity, 0302 clinical medicine, Kynurenic acid, DRE, dioxin response elements, CH, CH223191, LC–MS, liquid chromatography–mass spectrometry, IS, internal standard, VCR, vincristine, General Pharmacology, Toxicology and Pharmaceutics, GE, gastric emptying, IL-6, interleukin-6, PDB, protein data bank, Receptor, GFP, green fluorescence protein, MOI, multiplicity of infection, 0303 health sciences, ESI, electrospray ionization, IBD, inflammatory bowel disease, HE, hematoxylin and eosin, ELISA, enzyme-linked immunosorbent assay, 030220 oncology & carcinogenesis, IDO1, indoleamine 2,3-dioxygenase 1, Original Article, 1-MT, 1-methyl-tryptophan, DAI, disease activity index, RPMI 1640, Roswell Park Memorial Institute 1640, medicine.symptom, GPR35, medicine.drug, PMA, phorbol 12-myristate 13-acetate, Linag, linagliptin, Trp, tryptophan, Dens-Cl, N-diethyl-amino naphthalene-1-sulfonyl chloride, Inflammation, AG, AG490, Linagliptin, Dns-Cl, N-dimethyl-amino naphthalene-1-sulfonyl chloride, 03 medical and health sciences, PBS, phosphate buffer saline, FBS, fetal bovine serum, Downregulation and upregulation, GI, gastrointestinal transit, Vard, vardenafil, Gradually sensing, medicine, 030304 developmental biology, MRM, multiple-reaction monitoring, lcsh:RM1-950, KYN, kynurenine, BCA, bicinchoninic acid, lcsh:Therapeutics. Pharmacology, PMSF, phenylmethylsulfonyl fluoride, chemistry, ARNT, aryl hydrocarbon receptor nuclear translocator, ERK1/2, extracellular regulated protein kinases 1/2, LPS, lipopolysaccharides, BSA, bovine serum albumin, JAK2, janus kinase 2, Homeostasis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af930bc5ea3c9fbae9d582539b35a5fTest
https://doi.org/10.1016/j.apsb.2020.07.017Test -
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المؤلفون: Kaushalya Amunugama, Matthew J. Jellinek, Megan P. Kilroy, Carolyn J. Albert, Valerio Rasi, Daniel F. Hoft, Michael G.S. Shashaty, Nuala J. Meyer, David A. Ford
المصدر: Redox Biology
Redox Biology, Vol 48, Iss, Pp 102208-(2021)مصطلحات موضوعية: LPE, lysophosphatidylethanolamine, PMA, phorbol 12-myristate 13-acetate, Medicine (General), QH301-705.5, Clinical Biochemistry, Plasmalogens, HOCl, hypochlorous acid, MPO, myeloperoxidase, Biochemistry, PC, choline glycerophospholipid, Chlorolipids, VLC, very long chain, R5-920, 2-ClFA, 2-chlorofatty acid, Sepsis, HCl, hydrochloric acid, ESI MS/MS, electrospray ionization tandem mass spectrometry, Biology (General), PE, ethanolamine glycerophospholipid, Myeloperoxidase, TLC, thin layer chromatography, Organic Chemistry, FA, fatty acid, GC/MS, gas chromatography mass spectrometry, 2-ClFALD, 2-chlorofatty aldehyde, FALD, fatty aldehyde, Research Paper, Neutrophil activation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991be0461f8ad91bb141668ad24ed6d9Test
https://pubmed.ncbi.nlm.nih.gov/34902676Test -
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المؤلفون: Keun-Cheol Kim, Byung-Soo Ahn, Hyun Suk Jung, Han-Heom Na, Yoon-Jong Park, Jin Sung Park, Jae-Min Ryu, Bok-hye Kim
المصدر: Journal of Pharmacopuncture
Journal of Pharmacopuncture, Vol 24, Iss 2, Pp 68-75 (2021)مصطلحات موضوعية: medicine.medical_specialty, RM1-950, phorbol 12-myristate 13-acetate (PMA), dermal papilla, Internal medicine, Gene expression, medicine, Miscellaneous systems and treatments, Testosterone, Pharmacology, integumentary system, Chemistry, RZ409.7-999, Wnt signaling pathway, Hair follicle, alopecia, cannabidiol (CBD), Endocrinology, medicine.anatomical_structure, Dermal papillae, Complementary and alternative medicine, Catenin, testosterone, Medicine, Original Article, Therapeutics. Pharmacology, Signal transduction, Immunostaining, wnt/β-catenin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fd5bbcf3a59e632bf06ab2fbde33b1Test
https://pubmed.ncbi.nlm.nih.gov/34249397Test -
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المؤلفون: Jianglei Chen, Yanhong Du, Wenjing Wu, Siribhinya Benyajati, Dibyendu Chakraborty, Yusuke Takahashi, Xiang Ma, Yangxiong Li, Wentao Liang, Jian Xing Ma
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Very Low-Density Lipoprotein Receptor, Retinal Pigment Epithelium, Interphotoreceptor matrix, Biochemistry, LRP6, low-density lipoprotein receptor–related protein 6, Macular Degeneration, Mice, shedding, RFP, red fluorescent protein, AMD, age-related macular degeneration, VLDLRI, VLDLR variant I, Wnt Signaling Pathway, Mice, Knockout, lipoprotein receptor, Chemistry, Wnt signaling pathway, MT1, membrane type 1, LRP6, IPM, interphotoreceptor matrix, TIMP3, tissue inhibitor of metalloproteinase 3, gRNA, guide RNA, TCF, T-cell factor, Cell biology, MMP, matrix metalloproteinase, medicine.anatomical_structure, Ectodomain, VLDLRII, VLDLR variant II, LDLR, low-density lipoprotein receptor, Research Article, PMA, phorbol 12-myristate 13-acetate, 5-FAM, 5-carboxyfluorescein, RPE, retinal pigment epithelium, VLDL receptor, TNFα, tumor necrosis factor alpha, ADAM17 Protein, H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate, ROS, reactive oxygen species, Downregulation and upregulation, Protein Domains, CHX, cycloheximide, sVLDLR, soluble ectodomain of VLDLR, PKC, protein kinase C, medicine, Animals, Humans, Molecular Biology, Retinal pigment epithelium, ADAM, Cell Biology, VLDLR, very low-density lipoprotein receptor, Wnt signaling, Disease Models, Animal, Receptors, LDL, DCF, dichlorofluorescein, retinal degeneration, BSA, bovine serum albumin, ADAM17, a disintegrin and metalloprotease 17
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5974b7bf59a8584fad41d82734272403Test
https://pubmed.ncbi.nlm.nih.gov/34509473Test -
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المؤلفون: Ankush Prasad, Claudio Rossi, Renuka Ramalingam Manoharan, Michaela Sedlářová, Lorenzo Cangeloni, Deepak Rathi, Gabriella Tamasi, Pavel Pospíšil, Marco Consumi
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7424
مصطلحات موضوعية: Free Radicals, Organic Chemistry, General Medicine, bioactive compounds, antioxidants, nutraceuticals, monocyte, macrophage, reactive oxygen species, phorbol 12-myristate 13-acetate, protein modification, malondialdehyde, redox reactions, Catalysis, Computer Science Applications, Inorganic Chemistry, Oxidative Stress, Malondialdehyde, Humans, Physical and Theoretical Chemistry, Reactive Oxygen Species, Oxidation-Reduction, Molecular Biology, Spectroscopy
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c874290423a09a24092c2885377c0430Test
https://doi.org/10.3390/ijms23137424Test -
7Macrophage MerTK promotes profibrogenic cross-talk with hepatic stellate cells via soluble mediators
المؤلفون: Mirella Pastore, Alessandra Caligiuri, Chiara Raggi, Nadia Navari, Benedetta Piombanti, Giovanni Di Maira, Elisabetta Rovida, Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Krista Rombouts, Salvatore Petta, Fabio Marra
المساهمون: Pastore, Mirella, Caligiuri, Alessandra, Raggi, Chiara, Navari, Nadia, Piombanti, Benedetta, Di Maira, Giovanni, Rovida, Elisabetta, Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Rombouts, Krista, Petta, Salvatore, Marra, Fabio
المصدر: JHEP Reports. 4:100444
مصطلحات موضوعية: Hepatology, CM, conditioned medium, ECM, extracellular matrix, Gas-6, Gas-6, growth arrest-specific gene 6, HSC(s), hepatic stellate cells, KC(s), Kupffer cell(s), M-CSF, macrophage colony-stimulating factor, M2c-like macrophages, MerTK, Myeloid-epithelial-reproductive tyrosine kinase, NAFLD, non-alcoholic fatty liver disease, NASH, NASH, non-alcoholic steatohepatitis, PMA, phorbol 12-myristate 13-acetate, TGFβ1, transforming growth factor-β1, THP-1, TIMP1, tissue inhibitor of metalloproteinase 1, VEGF-A, vascular endothelial growth factor-A, liver fibrosis, siRNA, small-interfering RNA, Gas-6, liver fibrosis, M2c-like macrophages, NASH, THP-1, Gastroenterology, Internal Medicine, Immunology and Allergy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4426fd2abba675fb27730b5800bb5ccTest
https://doi.org/10.1016/j.jhepr.2022.100444Test -
8Dedifferentiation of Human Cardiac Myofibroblasts Is Independent of Activation of COX-2/PGE2 Pathway
المؤلفون: Vy Tran Luu, Sang Phan, Zhu-Qiu Jin
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3023
مصطلحات موضوعية: Inorganic Chemistry, Organic Chemistry, sense organs, macromolecular substances, General Medicine, COX-2, dedifferentiation, myofibroblast, PGE2, Phorbol 12-myristate 13-acetate, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy, Catalysis, Computer Science Applications
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7dec24bfbb866a040661f1620aa2c3bTest
https://doi.org/10.3390/ijms23063023Test -
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المؤلفون: Thorsten Maretzky, Stefan F. Lichtenthaler, Gisela Weskamp, Theresa T. Lu, Sebastien Monette, Jose Lora, Dorjee T.N. Shola, Chingwen Yang, Carl P. Blobel, Thomas M. Li
المصدر: The Journal of Biological Chemistry
The journal of biological chemistry 296, 100733-(2021). doi:10.1016/j.jbc.2021.100733مصطلحات موضوعية: 0301 basic medicine, Male, Cytoplasm, KI, knock-in, knock-in mutation in mice, Biochemistry, Mice, iRhom1 and 2, inactive Rhomboid proteins 1 and 2, ADAM17 Protein, membrane protein, myeloid cell, MFI, mean fluorescence intensity, Receptor, Sequence Deletion, TACE (TNFα converting enzyme), Bone growth, mEF, mouse embryonic fibroblast, Chemistry, Protein Stability, ddc, Cell biology, BMDM, bone-marrow-derived macrophage, TNFα, tumor necrosis factor α, Transmembrane domain, Phenotype, Protein destabilization, ddc:540, DV, donor vector, Female, Signal transduction, metabolism [Fibroblasts], Research Article, IL-6R, interleukin-6 receptor, PMA, phorbol 12-myristate 13-acetate, genetics [ADAM17 Protein], ADAM17 (a disintegrin and metalloprotease 17), 03 medical and health sciences, metabolism [ADAM17 Protein], cell surface enzyme, Protein Domains, CHX, cycloheximide, Gene knockin, Animals, Amino Acid Sequence, Molecular Biology, metabolism [Cytoplasm], 030102 biochemistry & molecular biology, Base Sequence, Cell Biology, chemistry [ADAM17 Protein], Sheddase, Fibroblasts, EGFR, epidermal growth factor receptor, Mice, Inbred C57BL, 030104 developmental biology, EPCAM, epithelial cell adhesion molecule, mES, mouse embryonic stem, CRISPR-Cas Systems, ADAM17, a disintegrin and metalloprotease 17
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ddba9cdef79f06d77f3f2a019dddabTest
https://pubmed.ncbi.nlm.nih.gov/33957124Test -
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المؤلفون: Yuh Lin Wu, Yen Yu Lin, David Sun
المصدر: Chinese Journal of Physiology, Vol 63, Iss 4, Pp 179-186 (2020)
مصطلحات موضوعية: 0301 basic medicine, endocrine system, akt, Physiology, protein phosphatase 2a, Wortmannin, 03 medical and health sciences, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Physiology (medical), QP1-981, Animals, Humans, Protein Phosphatase 2, Phosphorylation, Protein kinase B, Protein kinase C, PI3K/AKT/mTOR pathway, Inflammation, Granulosa Cells, Activator (genetics), Protein phosphatase 2, Okadaic acid, granulosa cell, Cell biology, Rats, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Female, Proto-Oncogene Proteins c-akt, phorbol 12-myristate 13-acetate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb15fb5ae51e583c8810aac0c9e043c2Test
https://pubmed.ncbi.nlm.nih.gov/32859885Test