المؤلفون: Judy C. Young, Mark Merchant, Ihsan Nijem, Thomas Gelzleichter, Surinder Kaur, William Mallet, Mally Romero, Ellen Filvaroff, Christophe Severin, Jing Peng, Youjun Chen, Zhong Zheng, Elaine Mai

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602f35b92f38a4e317349755783d4b4eTest
https://doi.org/10.1158/1535-7163.22499713Test

المؤلفون: Judy C. Young, Mark Merchant, Ihsan Nijem, Thomas Gelzleichter, Surinder Kaur, William Mallet, Mally Romero, Ellen Filvaroff, Christophe Severin, Jing Peng, Youjun Chen, Zhong Zheng, Elaine Mai

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698324299a1e8945ea2d58c1c0bc79a7Test
https://doi.org/10.1158/1535-7163.22499716.v1Test

المؤلفون: Judy C. Young, Mark Merchant, Ihsan Nijem, Thomas Gelzleichter, Surinder Kaur, William Mallet, Mally Romero, Ellen Filvaroff, Christophe Severin, Jing Peng, Youjun Chen, Zhong Zheng, Elaine Mai

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4f35c13437b18b0d84db54fef4380a6dTest
https://doi.org/10.1158/1535-7163.c.6536236Test

المؤلفون: Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Male, 0301 basic medicine, obesity, Medical Sciences, FGF21, Adipose tissue, Mice, 0302 clinical medicine, Weight loss, Homeostasis, Medicine, Multidisciplinary, biology, Middle Aged, Biological Sciences, Adipose Tissue, Female, Adiponectin, Antibody, medicine.symptom, FGF21 receptor activation, Adult, Agonist, medicine.medical_specialty, Adolescent, medicine.drug_class, 030209 endocrinology & metabolism, Antibodies, Food Preferences, Young Adult, 03 medical and health sciences, Internal medicine, Weight Loss, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, Aged, business.industry, Fibroblast growth factor receptor 1, Body Weight, medicine.disease, Obesity, Fibroblast Growth Factors, stomatognathic diseases, Macaca fascicularis, 030104 developmental biology, Endocrinology, biology.protein, food preference, business, metabolism, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18Test
https://doi.org/10.1073/pnas.2012073117Test

المؤلفون: Martin O'Rourke, Nicholas Charles Ray, Thomas Gelzleichter, Leah Schutt, Ellen Ingalla, Neville James Mclean, Xiaojing Wang, Stephen Daly, Yingqing Ran, Jiangpeng Liao, Tommy Lai, Yu Zhong, Jun Liang, Sharada Labadie, Lori Friedman, Amy Sambrone, Jun Li, Robert A. Blake, Tao Wang, Liu Zhiguo, Birong Zhang, Steven J. Hartman, Jae H. Chang, Wei Zhou, Jane Guan, Vidhi Mody, Jonathan White, Fabien Roussel, Antonio G. DiPasquale, Jason R. Zbieg, Daniel F. Ortwine, Amy Young, James R. Kiefer, Maia Vinogradova, Simon Charles Goodacre, Deepak Sampath, Tracy Kleinheinz, Xiaoping Zheng, Jennifer M. Giltnane, Lorn Kategaya, Ingrid E. Wertz, Matthew Gill, Ciara Metcalfe, Siew Kuen Yeap, John S. Wai, Jason Oeh, Michelle Nannini

المصدر: Journal of medicinal chemistry. 64(16)

مصطلحات موضوعية: Phases of clinical research, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Mice, Structure-Activity Relationship, Breast cancer, Dogs, In vivo, Drug Discovery, medicine, Animals, Humans, Dosing, Molecular Structure, Chemistry, Antagonist, Estrogen Receptor alpha, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Rats, Macaca fascicularis, Cell culture, Cancer research, MCF-7 Cells, Molecular Medicine, Female, Estrogen Receptor Antagonists, Carbolines

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee86fe3f8068fbb2ff9647a59eadb710Test
https://pubmed.ncbi.nlm.nih.gov/34251202Test

المؤلفون: Sharmila Rajan, Thomas Gelzleichter, Amos Baruch, Junichiro Sonoda, C. Andrew Boswell, Dale Stevens, Eric Stefanich, Danielle Mandikian, Kyra J. Cowan

المصدر: mAbs. 9:1379-1388

مصطلحات موضوعية: Male, 0301 basic medicine, Receptor complex, FGF21, medicine.drug_class, Receptor expression, Immunology, Drug Evaluation, Preclinical, Adipose tissue, CHO Cells, Pharmacology, Biology, Diet, High-Fat, Monoclonal antibody, 03 medical and health sciences, Cricetulus, Report, Cricetinae, medicine, Animals, Immunology and Allergy, Tissue Distribution, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Adiponectin, Fibroblast growth factor receptor 1, Antibodies, Monoclonal, Fibroblast Growth Factors, Mice, Inbred C57BL, Macaca fascicularis, 030104 developmental biology, Adipose Tissue, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe09bafc48ef65e54437fd42a8236afTest
https://doi.org/10.1080/19420862.2017.1373923Test

المؤلفون: Gerhard F. Weinbauer, Akihiro Arima, Chris Schuetz, Cynthia Woods, Hong Wang, Jane L. Grogan, Thomas Gelzleichter, Yutaka Chihaya, Gary Cain, Gunnar Habermann, Jim Xiao

المصدر: Reproductive Toxicology. 63:82-95

مصطلحات موضوعية: Male, 0301 basic medicine, Lymphocyte, Embryonic Development, Lymphocytosis, Antibodies, Monoclonal, Humanized, Toxicology, Immunoglobulin G, Fetal Development, Andrology, 03 medical and health sciences, Pregnancy, medicine, Animals, Mesenteric lymph nodes, Lymphotoxin-alpha, Maternal-Fetal Exchange, Lymph node, Pateclizumab, Fetus, biology, Embryo, Mammalian, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, Immunology, biology.protein, Female, Lymph Nodes, Lymph, Antibody, Dendritic Cells, Follicular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a2e69ba3906a3b5f46dd8a6489dc72Test
https://doi.org/10.1016/j.reprotox.2016.05.014Test

المؤلفون: Susan L. Limb, Lin Pan, Linda Nguyen, Yuan Chen, Thomas Gelzleichter, Cindy Burg

المصدر: Pulmonary pharmacologytherapeutics. 51

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Time Factors, Pyridones, Cmax, Administration, Oral, 030204 cardiovascular system & hematology, Gastroenterology, Drug Administration Schedule, Rats, Sprague-Dawley, 03 medical and health sciences, Idiopathic pulmonary fibrosis, 0302 clinical medicine, Pharmacokinetics, Oral administration, Internal medicine, medicine, Animals, Pharmacology (medical), Gastric emptying, business.industry, Stomach, digestive, oral, and skin physiology, Biochemistry (medical), Anti-Inflammatory Agents, Non-Steroidal, Pirfenidone, medicine.disease, Rats, medicine.anatomical_structure, 030228 respiratory system, Tolerability, Gastric Emptying, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fadbac9bf93b56c393cf4fd4780449Test
https://pubmed.ncbi.nlm.nih.gov/29944949Test

المؤلفون: Kyra J. Cowan, Feng Yang, Mark Z. Chen, Ambrose Williams, Terry Hudson, Shannon Liu, Nicole Valle, Timothy Tully, Junichiro Sonoda, Thomas Gelzleichter, Sharmila Rajan, Frank Macchi

المصدر: Journal of pharmacological and toxicological methods. 94(Pt 1)

مصطلحات موضوعية: 0301 basic medicine, Male, Bispecific antibody, Receptor complex, Mice, Obese, CHO Cells, Toxicology, Antibodies, Cell Line, 03 medical and health sciences, Mice, Cricetulus, Animals, Humans, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Related impurities, Obese Mice, Pharmacology, Manufacturing process, Chemistry, Membrane Proteins, Highly selective, Combinatorial chemistry, Mice, Inbred C57BL, Molecular Weight, stomatognathic diseases, Disease Models, Animal, Drug Combinations, 030104 developmental biology, HEK293 Cells, Product (mathematics), Immunoglobulin G, Drug product, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b66987db00744fc1e7acdc79bb85f9Test
https://pubmed.ncbi.nlm.nih.gov/29660397Test

المؤلفون: John C. Davis, Kun Peng, Thomas Gelzleichter, Laura Pascasio Harris, Alexandr Vilimovskij, Whittemore G. Tingley, Robert Kahn, Sofia Mosesova, Kyra J. Cowan, John D. Davis, Nageshwar Budha, Amos Baruch, Josh Lehrer

المصدر: The American journal of cardiology. 119(10)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Apolipoprotein B, Adolescent, Injections, Subcutaneous, Coronary Disease, 030204 cardiovascular system & hematology, Placebo, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Double-Blind Method, Risk Factors, Internal medicine, medicine, Humans, 030212 general & internal medicine, Aged, Aged, 80 and over, Inflammation, biology, Dose-Response Relationship, Drug, business.industry, Cholesterol, PCSK9, Antibodies, Monoclonal, Cholesterol, LDL, Middle Aged, Dose–response relationship, Endocrinology, chemistry, Monoclonal, biology.protein, Cytokines, lipids (amino acids, peptides, and proteins), Female, Antibody, Proprotein Convertase 9, Cardiology and Cardiovascular Medicine, business, Biomarkers, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56014790e6e7975770c47e8116c8b43Test
https://pubmed.ncbi.nlm.nih.gov/29448977Test