يعرض 1 - 10 نتائج من 429 نتيجة بحث عن '"Pedro A. Lazo"', وقت الاستعلام: 0.73s تنقيح النتائج
  1. 1
    The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

    المؤلفون: Eva Monte-Serrano, Patricia Morejón-García, Ignacio Campillo-Marcos, Aurora Campos-Díaz, Elena Navarro-Carrasco, Pedro A. Lazo

    المصدر: Epigenetics & Chromatin. 16

    مصطلحات موضوعية: Genetics, Molecular Biology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e9b1367a88df5966bf5c0d9ac5b9ff87Test
    https://doi.org/10.1186/s13072-023-00494-7Test


    أضف إلى المفضلة
  2. 2
    VRK1 variants at the cross road of Cajal body neuropathogenic mechanisms in distal neuropathies and motor neuron diseases

    المؤلفون: Pedro A. Lazo, Patricia Morejón-García

    المصدر: Neurobiology of Disease. 183:106172

    مصطلحات موضوعية: Neurology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c3d1956ba677979ac730a2974623d0bfTest
    https://doi.org/10.1016/j.nbd.2023.106172Test


    أضف إلى المفضلة
  3. 3
    The VRK1 chromatin kinase regulates the acetyltransferase activity of Tip60/KAT5 by sequential phosphorylations in response to DNA damage

    المؤلفون: Raúl García-González, Pedro A. Lazo, Elena Navarro-Carrasco, PATRICIA MOREJON, Eva Monte Serrano

    المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Junta de Castilla y León, Ministerio de Educación (España)

    المصدر: Biochimica et biophysica acta. Gene regulatory mechanisms. 1865(8)

    مصطلحات موضوعية: Biophysics, Acetylation, DNA, Biochemistry, Chromatin, Histones, VRK1, Histone, Tip60, Structural Biology, Genetics, Phosphorylation, Molecular Biology, DNA Damage

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c313a917c73a819b36331cbbd83ab05Test
    https://pubmed.ncbi.nlm.nih.gov/36280132Test


    أضف إلى المفضلة
  4. 4
    VRK1 Kinase Activity Modulating Histone H4K16 Acetylation Inhibited by SIRT2 and VRK-IN-1

    المؤلفون: Eva Monte Serrano, Pedro A. Lazo

    المصدر: International Journal of Molecular Sciences
    Volume 24
    Issue 5
    Pages: 4912

    مصطلحات موضوعية: Organic Chemistry, General Medicine, DNA damage response, Catalysis, Computer Science Applications, Inorganic Chemistry, VRK1, histone H4, SIRT2, Tip60, KAT5, Physical and Theoretical Chemistry, VRK-IN-1, Molecular Biology, Spectroscopy, acetylation

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d53ccb4b4a539befeae0949c1c8c971Test
    https://doi.org/10.3390/ijms24054912Test


    أضف إلى المفضلة
  5. 5
    Targeting histone epigenetic modifications and DNA damage responses in synthetic lethality strategies in cancer?

    المؤلفون: Pedro A. Lazo

    المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Junta de Castilla y León

    مصطلحات موضوعية: Lysine deacetylase, Cancer Research, Chromatin kinase, Lysine methylase, Oncology, Lysine acetylase, Lysine demethylase

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed06ad81e4250c87930ffd85f91445aTest
    http://hdl.handle.net/10261/283391Test


    أضف إلى المفضلة
  6. 6
    Dysfunctional Homozygous VRK1-D263G Variant Impairs the Assembly of Cajal Bodies and DNA Damage Response in Hereditary Spastic Paraplegia

    المؤلفون: Boris Keren, Pedro A. Lazo, Paulino Gómez-Puertas, Iñigo Marcos-Alcalde, Fanny Mochel, Patricia Morejón-García

    المساهمون: Ministerio de Educación (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Junta de Castilla y León, European Commission, Gestionnaire, HAL Sorbonne Université 5, Universidad de Salamanca, Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Digital.CSIC. Repositorio Institucional del CSIC
    instname
    Neurology Genetics
    Neurology Genetics, 2021, 7 (5), pp.e624. ⟨10.1212/nxg.0000000000000624⟩
    Neurology Genetics, American Academy of Neurology, 2021, 7 (5), pp.e624. ⟨10.1212/nxg.0000000000000624⟩
    Neurology: Genetics
    article-version (Version of Record) 3
    DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria

    مصطلحات موضوعية: Hereditary spastic paraplegia, DNA damage, All Neuromuscular Disease, Article, 03 medical and health sciences, 0302 clinical medicine, All Genetics, medicine, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Transcription factor, Genetics (clinical), 030304 developmental biology, Genetics, 0303 health sciences, biology, Kinase, Developmental disorders, Spastic paraplegia, medicine.disease, Activating transcription factor 2, nervous system diseases, 3. Good health, Histone, Cajal body, biology.protein, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Coilin, Neurology (clinical), 030217 neurology & neurosurgery

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b64dcd95cad61d6b908d829955dad1Test
    http://hdl.handle.net/10261/261383Test


    أضف إلى المفضلة
  7. 7
    Lysine methyltransferase inhibitors impair H4K20me2 and 53BP1 foci in response to DNA damage in sarcomas, a synthetic lethality strategy

    المؤلفون: Ignacio Campillo-Marcos, Eva Monte-Serrano, Elena Navarro-Carrasco, Raúl García-González, Pedro A. Lazo

    المساهمون: Ministerio de Economía y Competitividad (España), Junta de Castilla y León, Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España)

    المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2021)
    Digital.CSIC. Repositorio Institucional del CSIC
    instname
    Frontiers in Cell and Developmental Biology

    مصطلحات موضوعية: Ionizing radiation, Methyltransferase, DNA damage, DNA repair, QH301-705.5, Ionizing radiations, Histone methylation, Cell and Developmental Biology, 53BP1 foci, Tazemetostat, Epigenetics, H2AX foci, Biology (General), Original Research, biology, Chemistry, Cell Biology, Chromatin, MDC1, Cell biology, Histone, Doxorubicin, biology.protein, Chaetocin, ionizing radiation, Developmental Biology

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca79043c3dd5414a81e454bb5be47730Test
    http://hdl.handle.net/10261/261746Test


    أضف إلى المفضلة
  8. 8
    The human VRK1 chromatin kinase in cancer biology

    المؤلفون: Elena Navarro-Carrasco, Ignacio Campillo-Marcos, Raúl García-González, Pedro A. Lazo

    المساهمون: Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Junta de Castilla y León, European Commission, Ministerio de Economía y Competitividad (España)

    المصدر: Digital.CSIC. Repositorio Institucional del CSIC
    instname

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA damage, Proliferation, Synthetic lethality, Protein Serine-Threonine Kinases, 03 medical and health sciences, 0302 clinical medicine, Prophase, Neoplasms, Humans, Phosphorylation, Mitosis, Transcription factor, Cell Proliferation, biology, Chemistry, Intracellular Signaling Peptides and Proteins, DNA Repair Pathway, Prognosis, Chromatin, Up-Regulation, Cell biology, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Histone, Oncology, DNA-Damage response, 030220 oncology & carcinogenesis, MitosisTumor suppression, biology.protein, Transcription Factors

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ba69d6e4c63321eae7c9606a3c395eTest
    http://hdl.handle.net/10261/262267Test


    أضف إلى المفضلة
  9. 9
    Novel Dominant KCNQ2 Exon 7 Partial In-Frame Duplication in a Complex Epileptic and Neurodevelopmental Delay Syndrome

    المؤلفون: Pedro A. Lazo, Cesar Arjona, Alvaro Villarroel, Juan Luis García, Iñigo Marcos-Alcalde, Rogelio González-Sarmiento, Carmen Fons, Paulino Gómez-Puertas

    المساهمون: Agencia Estatal de Investigación (España), Ministerio de Economía y Competitividad (España), Junta de Castilla y León, Ministerio de Economía, Industria y Competitividad (España), Instituto de Salud Carlos III, Generalitat de Catalunya

    المصدر: International Journal of Molecular Sciences
    Digital.CSIC. Repositorio Institucional del CSIC
    instname
    International Journal of Molecular Sciences, Vol 21, Iss 4447, p 4447 (2020)

    مصطلحات موضوعية: 0301 basic medicine, Neuromotor delay, Calmodulin, Case Report, Catalysis, Cerebral palsy, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, Epilepsy, Exon, 0302 clinical medicine, Gene duplication, medicine, Physical and Theoretical Chemistry, Binding site, Molecular Biology, Gene, lcsh:QH301-705.5, Spectroscopy, Dystonia, Genetics, KCNQ2, biology, Organic Chemistry, General Medicine, medicine.disease, Computer Science Applications, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, biology.protein, 030217 neurology & neurosurgery

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d65b97002e4643391abec6c1ac89f9Test
    http://hdl.handle.net/10261/237983Test


    أضف إلى المفضلة
  10. 10
    VRK1 (Y213H) homozygous mutant impairs Cajal bodies in a hereditary case of distal motor neuropathy

    المؤلفون: Patricia Morejón-García, Lluís Armengol, Ana T. Marcos, José M. Navarro-Pando, Paulino Gómez-Puertas, Elena Martín-Doncel, Pedro A. Lazo, Maria Segura-Puimedon, Iñigo Marcos-Alcalde

    المساهمون: Junta de Castilla y León, Ministerio de Educación (España), Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), European Commission

    المصدر: DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
    Universidad Francisco de Vitoria
    Digital.CSIC. Repositorio Institucional del CSIC
    instname
    Annals of Clinical and Translational Neurology, Vol 7, Iss 5, Pp 808-818 (2020)
    Annals of Clinical and Translational Neurology
    DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Mutant, Coiled Bodies, Neurosciences. Biological psychiatry. Neuropsychiatry, SMN1, Protein Serine-Threonine Kinases, Muscular Atrophy, Spinal, 03 medical and health sciences, Consanguinity, 0302 clinical medicine, Mutant protein, medicine, Humans, Kinase activity, RC346-429, Research Articles, business.industry, General Neuroscience, Intracellular Signaling Peptides and Proteins, Spinal muscular atrophy, medicine.disease, Spinal muscular atrophies, Cell biology, 030104 developmental biology, Cajal body, Coilin, Neurology (clinical), Neurology. Diseases of the nervous system, business, 030217 neurology & neurosurgery, Research Article, RC321-571

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bc691e4ec95774dfa7597bbd272c69Test
    http://hdl.handle.net/10641/2009Test


    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS — أرسل هذا البحث بالبريد الإلكتروني — حفظ البحث