المؤلفون: Ufuk Erdogdu, Nadezda Dolgikh, Stephanie Laszig, Vinzenz Särchen, Michael T. Meister, Marek Wanior, Stefan Knapp, Cathinka Boedicker

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 109-119 (2022)
Neoplasia (New York, N.Y.)
Neoplasia

مصطلحات موضوعية: BH3 mimetics, PBMC, peripheral blood mononuclear cell, Cancer Research, chemical and pharmacologic phenomena, Antineoplastic Agents, Nerve Tissue Proteins, Receptors, Cell Surface, Apoptosis, PI, propidium iodide, BRD4, bromodomain-containing protein 4, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Biomimetics, hemic and lymphatic diseases, Cell Line, Tumor, Proto-Oncogene Proteins, Rhabdomyosarcoma, BRD, bromodomain, Humans, BET proteins, RC254-282, Original Research, EV, empty vector, zVAD.fmk, N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone, ATCC, American Type Culture Collection, mBCL-2, murine BCL-2, CI, combination index, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, hemic and immune systems, Drug Synergism, BET protein, Bromo- and Extra-Terminal protein, Peptide Fragments, Mitochondria, ERMS, embryonal rhabdomyosarcoma, ARMS, alveolar rhabdomyosarcoma, RMS, rhabdomyosarcoma, FCS, fetal calf serum, biological phenomena, cell phenomena, and immunity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbac6aac81f4d40d574992bf92415f7Test
https://doi.org/10.1016/j.neo.2021.11.012Test

المؤلفون: Chnasu Lee, Woong-Yang Park, Sung Noh Hong, Minae An, Je-Gun Joung, Dong Kyung Chang, Young-Ho Kim

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 789-808 (2022)

مصطلحات موضوعية: Tumor Necrosis Factor-Alpha, Prostaglandin E2, Cellular differentiation, Necroptosis, Population, PBS, phosphate-buffered saline, RC799-869, Biology, Receptors, G-Protein-Coupled, ER, endoplasmic reticulum, Intestinal Stem Cell, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Crohn Disease, DEG, differentially expressed gene, CD, Crohn’s disease, PGE2, prostaglandin E2, Humans, Viability assay, TUNEL, deoxyuride-5′-triphosphate biotin nick end labeling, Intestinal Mucosa, education, ANOVA, analysis of variance, NF-κB, nuclear factor kappa B, Original Research, scRNA-seq, single-cell RNA sequencing, TNF, tumor necrosis factor, education.field_of_study, Hepatology, CC3, cleaved caspase-3, Stem Cells, Intestinal Organoid, Gastroenterology, LGR5, Diseases of the digestive system. Gastroenterology, Intestinal epithelium, COX, cyclooxygenase, Organoids, ISC, intestinal stem cell, Cancer research, Tumor necrosis factor alpha, Stem cell, Crohn’s Disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1366d05d8f9fa7e6be064c7f2b8c07c9Test
https://doi.org/10.1016/j.jcmgh.2021.10.010Test

المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani

المصدر: Journal of Advanced Research

مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618e7dc6e2d535e1930d5f8c2bf7d7eTest
https://doi.org/10.1016/j.jare.2021.06.003Test

المؤلفون: Antônio Rafael Quadros Gomes, Ana Laura Gadelha Castro, Kelly Cristina Oliveira de Albuquerque, Sandro Percário, Valdicley Vieira Vale, Heliton Patrick Cordovil Brígido, Rommel Rodríguez Burbano, Liliane Almeida Carneiro, Marcelo de Oliveira Bahia, Natasha Costa da Rocha Galucio, Fábio Alberto de Molfeta, Everton Luiz Pompeu Varela, Maria Fâni Dolabela

المصدر: Toxicology Reports, Vol 8, Iss, Pp 1480-1487 (2021)
Toxicology Reports

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, BFS, bovine fetal serum, AST, aspartate aminotransferase, DMSO, dimethyl sulfoxide, Pharmacology, Toxicology, medicine.disease_cause, EDTA, ethylenediaminetetraacetic, OECD, Organization for Economic Co-Operation and Development, RA1190-1270, Eleutherin, FDMEp, dichloromethane fraction of Eleutherine plicata, BCRJ, Cell bank of Rio de Janeiro, MTT, ([3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]), Cytotoxicity, RPMI, Roswell Park Memorial Institute medium, DPPH, 2,2-diphenyl-1-picrylhydrazyl, Eleutherine, biology, Chemistry, Regular Article, TLC, tin layer chromatography, EEEp, ethanol extract of Eleutherine plicata, MD, molecular dynamics, TNFR, tumour necrosis fator receptor, HPLC, high performance liquid chromatography, Toxicity, DNA fragmentation, GOLD, Genetic Optimization for Ligand Docking, medicine.symptom, Caspase-8, IC50, 50 % cytotoxic concentration, DARP, dopamine releasing protein, Isoeleutherin, rpm, rotations per minute, DMEM, Dulbecco's Modified Eagle's Medium, ROS, reactive oxygen species, PDB, Protein Data Bank, ALT, alanine aminotransferase, FrAE, ethyl acetate fraction of Elutherine plicata, medicine, NMR, nuclear magnetic resonance, ComputingMethodologies_COMPUTERGRAPHICS, Eleutherine plicata, FADD, Fas associated death domain, GA, Genetic Algorithm, biology.organism_classification, RSMD, root mean square deviation, In vitro, NMU, N-methyl-N-nitrosurea, Eleutherol, Comet assay, Mechanism of action, Toxicology. Poisons, Genotoxicity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203384ee56884c6277fc2f84190f3cdfTest
https://doi.org/10.1016/j.toxrep.2021.07.015Test

المؤلفون: Po Hsuan Su, Chen Jei Tai

المصدر: Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 10, Iss 5, Pp 429-433 (2020)

مصطلحات موضوعية: Oncology, Traditional Chinese medicine (TCM), medicine.medical_specialty, AESN, aqueous extract of Solanum nigrum, ALT, alanine transaminase, Cancer therapy, lcsh:Medicine, IC50, half maximal inhibitory concentration, Review Article, Traditional Chinese medicine, Aqueous extract of Solanum nigrum (AESN), Mini review, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, SQDBT, Shi Quan Da Bu Tang, ROS, reactive oxygen species, Autophagic pathway, AST, aspartate transaminase, Internal medicine, medicine, Paronychia, business.industry, SN, Solanum nigrum, lcsh:R, Hepatotoxicity, Cancer, medicine.disease, EGFR, epidermal growth factor receptor, Cancer treatment, Integrative therapy, Complementary and alternative medicine, Apoptotic cell death, Hematotoxicity, Cancer cell, TCM, traditional Chinese medicine, business, EMT, epithelial–mesenchymal transition

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d326b98ac836cf3c372c46cedb8eb4Test
https://doi.org/10.1016/j.jtcme.2019.07.001Test

المؤلفون: Gloria Gutiérrez-Venegas, Berenice Fernández-Rojas, José Pedraza-Chaverri, Gustavo Ignacio Vázquez-Cervantes

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 101-108 (2020)

مصطلحات موضوعية: Antioxidant, Health, Toxicology and Mutagenesis, medicine.medical_treatment, ERK, extracellular signal-regulated kinases, 010501 environmental sciences, Toxicology, medicine.disease_cause, 01 natural sciences, GPx-1, glutathione peroxidase-1, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, chemistry.chemical_compound, 0302 clinical medicine, Carboxy-H2DCFDA, 6-carboxy-2´,7´ dichlorodihydrofluorescein diacetate, LTA, lipoteichoic acid, GSH, glutathione, ROS production, NOS, nitric oxide synthase, chemistry.chemical_classification, biology, Chemistry, OH•, hydroxyl radical, Glutathione peroxidase, Regular Article, respiratory system, IE, infective endocarditis, Catalase, H2O2, hydrogen peroxide, O2•¯, superoxide radical, Antioxidant enzymes, lipids (amino acids, peptides, and proteins), Lipoteichoic acid, FDA, fluorescein diacetate, JNK, c-jun N-terminal kinases, SOD-1, superoxide dismutase-1, AKT, protein kinase B, ONOO¯, peroxynitrite anion, Microbiology, RNS, reactive nitrogen species, Superoxide dismutase, 03 medical and health sciences, ROS, reactive oxygen species, lcsh:RA1190-1270, medicine, Nrf2, nuclear factor (erythroid-derived 2)-like 2, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, NO, nitric oxide, Reactive oxygen species, Glutathione, Oxidative stress, biology.protein, CAT, catalase, Infective endocarditis, DHE, dihydroethidium, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51499fcc0fda5a05a7ea44fe2d3e0ae6Test
https://doi.org/10.1016/j.toxrep.2019.12.007Test

المؤلفون: Akalesh K. Verma, Sweta Singh

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 443-452 (2020)

مصطلحات موضوعية: PBMC, peripheral blood mononuclear cell, Murraya, Health, Toxicology and Mutagenesis, FL, fidelity level, MTT, 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide, 010501 environmental sciences, Biology, Mitochondrion, Toxicology, 01 natural sciences, 03 medical and health sciences, ROS, reactive oxygen species, 0302 clinical medicine, ΔΨm, mitochondrial membrane potential, lcsh:RA1190-1270, Hibiscus sabdariffa, Medicinal plants, Mode of action, RFC, Relative frequency of citation, Murraya koenigii, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, DPPH, 2,2-diphenyl-1-picrylhydrazyl, Moringa oleifera, chemistry.chemical_classification, Reactive oxygen species, Traditional medicine, DL, Dalton’s ascites lymphoma, Lablab purpureus, Regular Article, AO/EB, acridine orange and ethidium bromide, biology.organism_classification, IU, International unit, Phytochemical, chemistry, Apoptosis, Annona reticulate, Euphorbia hirta, 030217 neurology & neurosurgery, OD, Optical density

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46ec18948347ab559b552f4a05ea262Test
https://doi.org/10.1016/j.toxrep.2020.02.016Test

المؤلفون: Bin Sun, Huanmin Niu, Hong-Xiang Lou, Fang Wang, Huiqing Yuan, Qian Wang, Xiao-Tian Ji, Effat Un Nesa, Wenjian Liu, Lilin Qian, Yanhai Luo

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 923-936 (2019)

مصطلحات موضوعية: BUN, blood urea nitrogen, medicine.medical_treatment, DMSO, dimethyl sulfoxide, SASP, AST, transaminase, NF-κB, Doc, docetaxel, Doxo, doxorubicin, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, chemistry.chemical_compound, 0302 clinical medicine, CI, combinatory index, TFEB, transcription factor EB, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, CM, conditioned media, PGPH, peptidylglutamyl hydrolyzing, Chemistry, CDDP, cisplatin, ALT, glutamic-pyruvic transaminase, EdU, 5-ethynyl-2′-deoxyuridine, Phenotype, Sv, starvation, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, LPS, lipopolysaccharide, medicine.drug, Original article, TCGA, the Cancer Genome Atlas, NF-κB, nuclear factor-κB, SASP, senescence-associated secretory phenotype, PI, propidium iodide, Mar-M, Marchantin M, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Doxorubicin, Secretion, Fibroblast, 030304 developmental biology, TFEB, Chemotherapy, lcsh:RM1-950, fungi, Marchantin M, CREA, creatinine, lcsh:Therapeutics. Pharmacology, CT-like, both chymotrypsin-like, Drug resistance, Tg, thapsigargin, Cancer research, SA-β-gal, senescence-associated β-galactosidase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bcbf93a8ce076cb653df6c09386080Test
https://doi.org/10.1016/j.apsb.2019.08.007Test

المؤلفون: Annalise, Pfaff, Anna, Chernatynskaya, Hannah, Vineyard, Nuran, Ercal

المصدر: Biochemistry and Biophysics Reports

مصطلحات موضوعية: FDA, United States Food and Drug Administration, GSSG, glutathione disulfide, ATCC, American Type Culture Collection, OH•, hydroxyl radical, PBS, phosphate-buffered saline, NAC, N-acetylcysteine, tBHP, tert-butyl hydroperoxide, 7-AAD, 7-aminoactinomycin D, Glutathione, Cataract, Lens, HLE B-3, human (eye) lens epithelial cell line B-3, ROS, reactive oxygen species, FBS, fetal bovine serum, Oxidative stress, H2O2, hydrogen peroxide, Thiol, Carboxy-H2DCFDA, 6-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, GSH, glutathione, MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), NACA, N-acetylcysteine amide, MPG, N-(2-mercaptopropionyl)glycine, Antioxidant, EMEM, Eagle's minimum essential medium, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c6ad6a048992849fbae63780b9c9e9c3Test
https://pubmed.ncbi.nlm.nih.gov/35128081Test

المؤلفون: Jinlan, Yang, Shuo, Wang, Tao, Zhang, Yuqing, Sun, Lifeng, Han, Prince Osei, Banahene, Qi, Wang

المصدر: Current Research in Toxicology

مصطلحات موضوعية: Cassiae semen, IdMOC, Integrated discrete multiple organ co-culture, AQ, Anthraquinone, CYP, Cytochrome P450, GLM, General linear models, IdMOC system, Article, QSAR, Quantitative structure-activity relationship, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Anthraquinone, C. semen, Cassiae semen, QSAR models, TCM, Traditional Chinese medicine, ComputingMethodologies_COMPUTERGRAPHICS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::3a97d1797cd7d95b9e0277a1151fdc12Test
https://pubmed.ncbi.nlm.nih.gov/34345866Test