Opium and Heroin Alter Biochemical Parameters of Human's Serum
| العنوان: | Opium and Heroin Alter Biochemical Parameters of Human's Serum |
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| المؤلفون: | Divsalar Kouros, Tahereh Haghpanah, Mahmoudi Zarandi Minoo, Afarinesh Mohammadreza |
| المصدر: | The American Journal of Drug and Alcohol Abuse. 36:135-139 |
| بيانات النشر: | Informa UK Limited, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Blood Glucose, Male, medicine.medical_specialty, Medicine (miscellaneous), Iran, Opium, Heroin, chemistry.chemical_compound, Internal medicine, medicine, Humans, Blood urea nitrogen, Creatinine, Triglyceride, business.industry, Cholesterol, Opioid-Related Disorders, Uric Acid, Surgery, Psychiatry and Mental health, Clinical Psychology, Cross-Sectional Studies, Endocrinology, chemistry, Case-Control Studies, Potassium, Uric acid, Calcium, business, Homeostasis, medicine.drug |
| الوصف: | Iran is a significant consumer of opium, and, generally, of opioids, in the world. Addiction is one of the important issues of the 21st century and is an imperative issue in Iran. Long-term consumption of opioids affects homeostasis.To determine the effects of opium and heroin consumption on serum biochemical parameters.In a cross-sectional study, subjects who had consumed heroin (n = 35) or opium (n = 42) for more than two years and 35 nonaddict volunteers as the control group were compared in regard to various biochemical parameters such as fasting blood sugar (FBS), Na(+), K(+), Ca(2+), blood urea nitrogen (BUN), uric acid (UA), triglyceride (TG), cholesterol, creatinine, and total protein. Chromatography was used to confirm opioid consumption, and the concentration of biochemical parameters was determined by laboratory diagnostic tests on serum.No significant differences were found in Na(+), Ca(2+), BUN, UA, TG, creatinine, and total protein concentrations among the three groups. FBS, K(+), and UA levels were significantly lower in opium addicts compared to the control group. Serum Ca(2+) concentration of heroin addicts showed a significant decrease compared to that of the control group. Both addict groups showed a significant decrease in serum cholesterol levels.Chronic use of opium and heroin can change serum FBS, K(+), Ca(2+), UA, and cholesterol.This study, one of few on the effects of opium on serum biochemical parameters in human subjects, has the potential to contribute to the investigation of new approaches for further basic studies. |
| تدمد: | 1097-9891 0095-2990 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d376ef9f4da7603f1c2dac7cf783e26eTest https://doi.org/10.3109/00952991003734277Test |
| رقم الانضمام: | edsair.doi.dedup.....d376ef9f4da7603f1c2dac7cf783e26e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10979891 00952990 |
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