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المؤلفون: Tiziana Bonifacino, Laura Micheli, Carola Torazza, Carla Ghelardini, Carlo Farina, Giambattista Bonanno, Marco Milanese, Lorenzo Di Cesare Mannelli, Michael W. Scherz
المصدر: Cells; Volume 11; Issue 24; Pages: 4027
مصطلحات موضوعية: oxaliplatin-induced neuropathic pain, synaptosomes, allodynia, hyperalgesia, NMDA-induced glutamate release, allosteric modulation, General Medicine
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6fe2956c16add49eacecdf2d46ae5dTest
https://pubmed.ncbi.nlm.nih.gov/36552791Test -
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المؤلفون: Beáta Lemli, Zuzana Lomozová, Tamás Huber, András Lukács, Miklós Poór
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14007
مصطلحات موضوعية: Organic Chemistry, Biliverdine, Bilirubin, General Medicine, Heme, Ligands, Catalysis, Computer Science Applications, Inorganic Chemistry, human serum albumin, warfarin, Sudlow’s site I, heme site, allosteric modulation, Humans, Hemin, Warfarin, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy, Serum Albumin
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5955b08b955e804d15e4267d498eb36aTest
https://pubmed.ncbi.nlm.nih.gov/36430492Test -
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المؤلفون: Mingfei Ji, Zongtao Chai, Jie Chen, Gang Li, Qiang Li, Miao Li, Yelei Ding, Shaoyong Lu, Guanqun Ju, Jianquan Hou
المصدر: Molecules; Volume 27; Issue 13; Pages: 4149
مصطلحات موضوعية: Male, Carcinoma, Hepatocellular, Organic Chemistry, Liver Neoplasms, SUMO-1 Protein, Pharmaceutical Science, SUMO, SENP1, molecular dynamics simulation, allostery, allosteric modulation, Analytical Chemistry, Cysteine Endopeptidases, Chemistry (miscellaneous), Drug Discovery, Mutation, Molecular Medicine, Humans, Physical and Theoretical Chemistry, Peptide Hydrolases
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820dada529fce4def4522d362bfea127Test
https://pubmed.ncbi.nlm.nih.gov/35807394Test -
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المؤلفون: Damian Bartuzi, Agnieszka Anna Kaczor, Tomasz Wróbel
المصدر: Molecules. 28:178
مصطلحات موضوعية: allosteric modulation, molecular modeling, Organic Chemistry, Biochemistry and Molecular Biology, Pharmaceutical Science, Pharmacology and Toxicology, Farmakologi och toxikologi, Analytical Chemistry, G protein-couple receptors, Chemistry (miscellaneous), Drug Discovery, dopamine D-2 receptor, drug synthesis, Molecular Medicine, Physical and Theoretical Chemistry, Biokemi och molekylärbiologi
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0593082b9078eade3f6256bf9c8a7c27Test
https://doi.org/10.3390/molecules28010178Test -
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المساهمون: Leboffe, L., Di Masi, A., Polticelli, F., Trezza, V., Ascenzi, P., Leboffe, Lori, di Masi, Alessandra, Polticelli, Fabio, Trezza, Viviana, Ascenzi, Paolo
المصدر: Current Medicinal Chemistry. 27:4907-4931
مصطلحات موضوعية: Drug, Competitive modulation of drug binding, Drug carrier, media_common.quotation_subject, Allosteric regulation, Ligand, Serum Albumin, Human, Endogeny, Plasma protein binding, Ligands, 010402 general chemistry, 01 natural sciences, Biochemistry, 03 medical and health sciences, Pharmacokinetics, Drug Discovery, medicine, Humans, Binding site, 030304 developmental biology, media_common, Pharmacology, 0303 health sciences, Binding Sites, Chemistry, Organic Chemistry, Binding Site, Human serum albumin, 0104 chemical sciences, body regions, Drug recognition, Structural basi, competitive modulation of drug binding, embryonic structures, Allosteric modulation of drug binding, Molecular Medicine, Human, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a0aea0285eabd57d39b5c5c07c1eb8Test
https://doi.org/10.2174/0929867326666190320105316Test -
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المؤلفون: Zoltán Orgován, György M. Keserű, György G. Ferenczy
المصدر: Chemmedchem
مصطلحات موضوعية: metabotropic glutamate receptors, Allosteric regulation, Subtype selectivity, Molecular Dynamics Simulation, Ligands, Receptors, Metabotropic Glutamate, 01 natural sciences, Biochemistry, GPCRs, Structure-Activity Relationship, Allosteric Regulation, Drug Discovery, Humans, Benzopyrans, General Pharmacology, Toxicology and Pharmaceutics, molecular switches, Receptor, G protein-coupled receptor, Pharmacology, Molecular switch, allosteric modulation, water networks, 010405 organic chemistry, Chemistry, Organic Chemistry, Minireviews, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Pyrimidines, Metabotropic glutamate receptor, Molecular Medicine, Functional activity, Minireview, Neuroscience, Allosteric Site
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b307cc20f1b52c1b8b66a060d3c227Test
https://doi.org/10.1002/cmdc.202000444Test -
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المؤلفون: Richard, Ågren, Kristoffer, Sahlholm
المصدر: Biomedicines
مصطلحات موضوعية: induced-fit binding, secondary binding pocket, allosteric modulation, G protein-coupled receptors, Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::2e4cb45052a6887c8721a34cbe3bc909Test
https://pubmed.ncbi.nlm.nih.gov/35052702Test -
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المؤلفون: Andrea Gogos, Geoffrey Pavey, Shaun Hopper, Brian Dean
المصدر: International Journal of Neuropsychopharmacology
مصطلحات موضوعية: Male, Allosteric modulator, hippocampus, striatum, Allosteric regulation, Hippocampus, Quinolones, musccarinic M1 receptor, Tritium, Regular Research Articles, Radioligand Assay, chemistry.chemical_compound, Allosteric Regulation, mental disorders, medicine, Humans, Pharmacology (medical), Cerebral Cortex, Pharmacology, business.industry, Dentate gyrus, Receptor, Muscarinic M1, Muscarinic acetylcholine receptor M1, Middle Aged, N-Methylscopolamine, medicine.disease, Corpus Striatum, schizophrenia, Psychiatry and Mental health, medicine.anatomical_structure, positive allosteric modulation, chemistry, Cerebral cortex, Schizophrenia, Case-Control Studies, Autoradiography, Female, business, Xanomeline, Neuroscience, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19f7d8d3a17931a1a122c536c895d4dTest
https://doi.org/10.1093/ijnp/pyz045Test -
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المؤلفون: Borroto-Escuela, Dasiel O., Ferraro, Luca, Fuxe, Kjell
المصدر: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2022)مصطلحات موضوعية: Pharmacology, Opinion, allosteric modulation, adenosine heteroreceptor complexes, striatal-enriched protein tyrosine phosphatase, Therapeutics. Pharmacology, RM1-950, G protein coupled receptors (GPCR), dopmaine heteroreceptor complexes, mu-opioid heteroreceptor complexes, adenosine receptors, receptor-receptor interactions, NO
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::74923d5bdbb93dbed01372315e24c805Test
https://pubmed.ncbi.nlm.nih.gov/35069202Test