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المؤلفون: Najia Khurram, Peter J. Mullen, Robert J. Hamilton, Sangeet Ghai, Mohamad Elbaz, Joseph Longo, Theodorus van der Kwast, Emily Branchard, Neil Fleshner, Mehdi Masoomian, Linda Z. Penn, Eric Chen, Karen Hersey, Dianne Chadwick, David W. Andrews
المصدر: Prostate Cancer and Prostatic Diseases
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Cancer therapy, Urology, medicine.medical_treatment, Apoptosis, Pilot Projects, Article, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Prostate, Preoperative Care, Biopsy, Biomarkers, Tumor, medicine, Humans, Fluvastatin, Aged, Prostatectomy, medicine.diagnostic_test, Caspase 3, business.industry, Prostatic Neoplasms, Middle Aged, medicine.disease, Neoadjuvant Therapy, 3. Good health, Ki-67 Antigen, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Disease Progression, Immunohistochemistry, Hydroxymethylglutaryl CoA Reductases, business, medicine.drug, Lipoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928230d134347a4cfd7a1d049f2ee4c2Test
https://doi.org/10.1038/s41391-020-0221-7Test -
2
المؤلفون: Peter J. Mullen, Rosemary Yu, Jenna E. van Leeuwen, Wail Ba-alawi, Joseph Longo, Linda Z. Penn, Benjamin Haibe-Kains
المصدر: Cancer Research. 78:1347-1357
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Statin, medicine.drug_class, Protein Prenylation, Farnesyl pyrophosphate, Mevalonic Acid, Apoptosis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Polyisoprenyl Phosphates, Prenylation, Neoplasms, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Humans, HRAS, Fluvastatin, Cell Proliferation, Zinc Finger E-box-Binding Homeobox 1, 3. Good health, 030104 developmental biology, Oncology, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer cell, ras Proteins, Cancer research, Protein prenylation, lipids (amino acids, peptides, and proteins), Ras superfamily, Sesquiterpenes, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172d0af6f57cd0142de641e82bd842fdTest
https://doi.org/10.1158/0008-5472.can-17-1231Test -
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المؤلفون: Peter J. Mullen, Rosemary Yu, Michael C. Archer, Joseph Longo, Linda Z. Penn
المصدر: Nature Reviews Cancer. 16:718-731
مصطلحات موضوعية: 0301 basic medicine, Cell signaling, animal structures, viruses, General Mathematics, Mevalonic Acid, Biology, complex mixtures, 03 medical and health sciences, Neoplasms, medicine, Humans, Applied Mathematics, Cancer, hemic and immune systems, Metabolism, medicine.disease, Cell biology, Metabolic pathway, 030104 developmental biology, Cancer metabolism, Mevalonate pathway, Signal transduction, Signalling pathways, Metabolic Networks and Pathways, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44579fb2e893e634174ba9ab66ffe337Test
https://doi.org/10.1038/nrc.2016.76Test -
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المؤلفون: Peter J. Mullen, Ahmed Aman, Linda Z. Penn, Benjamin Haibe-Kains, Aaliya Tamachi, Wail Ba-alawi, Rima Al-awar, David W. Cescon, Cornelia Redel, Cheryl H. Arrowsmith, Yu-Jia Shiah, Dharmendra Dingar, Brian Raught, William B. Tu, Corey Lourenco, Paul C. Boutros
المصدر: Cancer cell. 34(4)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Carcinogenesis, Gene Expression, Biology, medicine.disease_cause, Malignant transformation, Epigenesis, Genetic, 03 medical and health sciences, Mice, Cell Line, Tumor, Histocompatibility Antigens, Histone methylation, medicine, Animals, Humans, Epigenetics, Promoter Regions, Genetic, Psychological repression, Chromatin binding, Cell Biology, Histone-Lysine N-Methyltransferase, 3. Good health, Cell biology, 030104 developmental biology, Oncology, Histone methyltransferase, Histone Methyltransferases, Epigenetic therapy, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f0fd34332be5f88813a6d939006c6aTest
https://pubmed.ncbi.nlm.nih.gov/30367118Test -
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المؤلفون: Rosemary Yu, Suzanne Trudel, Aleksandra A. Pandyra, Janice T. Pong, Manpreet Kalkat, Peter J. Mullen, Karl S. Lang, Aaron D. Schimmer, Mark D. Minden, Linda Z. Penn, Zhihua Li
المصدر: Cancer Research. 74:4772-4782
مصطلحات موضوعية: Hydroxymethylglutaryl-CoA Synthase, Male, Cancer Research, Statin, medicine.drug_class, Medizin, Mevalonic Acid, Antineoplastic Agents, Apoptosis, Mevalonic acid, Pharmacology, Biology, Mice, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Dipyridamole, Potentiator, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, Oncology, chemistry, Leukocytes, Mononuclear, lipids (amino acids, peptides, and proteins), Mevalonate pathway, Sterol regulatory element-binding protein 2, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Multiple Myeloma, Sterol Regulatory Element Binding Protein 2, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2261eae78d1bfa3221fb79891532d0bTest
https://doi.org/10.1158/0008-5472.can-14-0130Test -
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المؤلفون: Peter J. Mullen, Karin Brecht, Swarna Maseneni, Stephan Krähenbühl, Andrea Felser, Anja Zahno, Peter W. Lindinger
المصدر: Biochimica et biophysica acta
مصطلحات موضوعية: Simvastatin, Blotting, Western, Cell Respiration, Muscle Fibers, Skeletal, Muscle Proteins, Apoptosis, Mitochondrion, Biology, Real-Time Polymerase Chain Reaction, Mice, 03 medical and health sciences, Oxygen Consumption, 0302 clinical medicine, Geranylgeranylation, medicine, Animals, Humans, Myocyte, RNA, Messenger, Insulin-Like Growth Factor I, Phosphorylation, Molecular Biology, Protein kinase B, Cells, Cultured, 030304 developmental biology, Membrane Potential, Mitochondrial, Rap1, 0303 health sciences, SKP Cullin F-Box Protein Ligases, Toxicity, Reverse Transcriptase Polymerase Chain Reaction, Myogenesis, Anticholesteremic Agents, Akt, rap1 GTP-Binding Proteins, Statin, Skeletal muscle, Hep G2 Cells, Cell Biology, Mitochondria, 3. Good health, Cell biology, medicine.anatomical_structure, Signal transduction, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8ad8c0d17ed95ea7909a7cab539b08Test
https://doi.org/10.1016Test/j .bbamcr.2011.07.019 -
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المصدر: Biochemical Pharmacology. 79:1200-1209
مصطلحات موضوعية: Simvastatin, medicine.medical_specialty, Glycosylation, Ubiquinone, Muscle Fibers, Skeletal, Protein Prenylation, Biochemistry, chemistry.chemical_compound, Muscular Diseases, Internal medicine, medicine, Humans, Myocyte, RNA, Messenger, cardiovascular diseases, Myopathy, Cells, Cultured, Pharmacology, biology, Cholesterol, Myogenesis, nutritional and metabolic diseases, Skeletal muscle, Hep G2 Cells, Endocrinology, medicine.anatomical_structure, Receptors, LDL, chemistry, HMG-CoA reductase, biology.protein, Protein prenylation, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, medicine.symptom, Sterol Regulatory Element Binding Protein 2, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1063186061476f284f227509ab0244Test
https://doi.org/10.1016Test/j .bcp.2009.12.007 -
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المؤلفون: Mahadeo A. Sukhai, Peter J. Mullen, Neil MacLean, Bozhena Jhas, Linda Z. Penn, John E. Dick, Stephanie Z. Xie, Marko Skrtic, Carolyn A. Goard, Mark D. Minden, Wei Xu, Feng-Hsu Lin, Danny V. Jeyaraju, Timothy E. Chung, Swayam Prabha, Aaron D. Schimmer, Marcela Gronda, Yulia Jitkova, Rose Hurren, Ian M. Rogers, Shrivani Sriskanthadevan, Xiaoming Wang, Rob C. Laister
المصدر: Blood. 125(13)
مصطلحات موضوعية: Myeloid, Cellular respiration, Immunology, Cell Respiration, Respiratory chain, Mitochondrion, Biology, medicine.disease_cause, Biochemistry, Electron Transport, Oxygen Consumption, hemic and lymphatic diseases, medicine, Tumor Cells, Cultured, Humans, neoplasms, Myeloid Neoplasia, Cell Death, Respiratory chain complex, Cell Biology, Hematology, medicine.disease, Leukemia, Haematopoiesis, Leukemia, Myeloid, Acute, Oxidative Stress, medicine.anatomical_structure, Cancer research, Mitochondrial Size, Reactive Oxygen Species, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee918c50a81b0e83f998a978a4aa41b5Test
https://pubmed.ncbi.nlm.nih.gov/25631767Test -
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المؤلفون: Natalie Meyer, Peter J. Mullen, Christina Bros, Amanda R. Wasylishen, Michelle Chan-Seng-Yue, Pak Kei Chan, Ling Huang, Linda Z. Penn, Paul C. Boutros, William B. Tu, Brian Raught, Dharmendra Dingar, Manpreet Kalkat
المصدر: Cancer research. 73(21)
مصطلحات موضوعية: Cancer Research, Chromatin Immunoprecipitation, Mutant, Blotting, Western, Apoptosis, Biology, Regulatory Sequences, Nucleic Acid, medicine.disease_cause, Real-Time Polymerase Chain Reaction, Colony-Forming Units Assay, Proto-Oncogene Proteins c-myc, Neuroblastoma, Oxygen Consumption, medicine, Biomarkers, Tumor, Cell Adhesion, Humans, RNA, Messenger, Phosphorylation, Mammary Glands, Human, Gene, Cells, Cultured, Cell Proliferation, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Epithelial Cells, Gene expression profiling, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, Oncology, Regulatory sequence, Mutation, Cancer research, Female, Carcinogenesis, Chromatin immunoprecipitation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3054f2ff0d2af3337624d01e7dff25caTest
https://pubmed.ncbi.nlm.nih.gov/24030976Test -
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المؤلفون: Massimiliano Donzelli, Peter J. Mullen, Réjane Morand, Liliane Todesco, David Fischer-Barnicol, Stephan Krähenbühl
المصدر: Therapeutic drug monitoring
مصطلحات موضوعية: Adult, medicine.medical_specialty, Organic Cation Transport Proteins, Drug Administration Schedule, Cell Line, Excretion, Kidney Tubules, Proximal, 03 medical and health sciences, 0302 clinical medicine, In vivo, Internal medicine, Carnitine, medicine, Homeostasis, Humans, Pharmacology (medical), Acetylcarnitine, Solute Carrier Family 22 Member 5, 030304 developmental biology, Pharmacology, 0303 health sciences, Chemistry, Valproic Acid, Transporter, Biological Transport, 3. Good health, Betaine, Endocrinology, HEK293 Cells, Renal physiology, Carnitine biosynthesis, Female, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b019db68d7df35b89b7dab7af6640c30Test
https://pubmed.ncbi.nlm.nih.gov/22743351Test