نتائج البحث - "Peter J. Mullen"

1

Methionine restriction forces Epstein-Barr virus out of latency

المؤلفون: Sriraksha Bharadwaj Kashyap, Racheal Mulondo, Peter J. Mullen

المصدر: Cell metabolism. 34(9)

مصطلحات موضوعية: Epstein-Barr Virus Infections, Herpesvirus 4, Human, Methionine, Physiology, Humans, Cell Biology, Molecular Biology, Virus Latency

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf751375f4bf59a3174c75f30514b5ebTest
https://pubmed.ncbi.nlm.nih.gov/36070681Test

2

SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition

المؤلفون: Nedas Matulionis, Peter J. Mullen, Arunachalam Ramaiah, Chandani Sen, Samuel W. French, Vaithilingaraja Arumugaswami, Ernst W. Schmid, Robert Damoiseaux, Kathrin Plath, Milica Momcilovic, Brigitte N. Gomperts, David B. Shackelford, Arunima Purkayastha, Gustavo Garcia, Justin Langerman, Heather R. Christofk

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature communications, vol 12, iss 1

مصطلحات موضوعية: 0301 basic medicine, viruses, Glutamine, General Physics and Astronomy, mTORC1, Virus Replication, 0302 clinical medicine, Chlorocebus aethiops, 2.1 Biological and endogenous factors, Aetiology, skin and connective tissue diseases, Lung, Multidisciplinary, respiratory system, Pyruvate carboxylase, Cell biology, Infectious Diseases, Mechanisms of disease, 5.1 Pharmaceuticals, TOR signalling, Benzamides, Respiratory, Mucosal immunology, Development of treatments and therapeutic interventions, Infection, Science, Morpholines, Citric Acid Cycle, Biology, Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, Animals, Humans, Naphthyridines, Protein Kinase Inhibitors, Vero Cells, Pyruvate Carboxylase, SARS-CoV-2, HEK 293 cells, COVID-19, Pneumonia, General Chemistry, Metabolism, biochemical phenomena, metabolism, and nutrition, respiratory tract diseases, 030104 developmental biology, Glucose, HEK293 Cells, Pyrimidines, Viral replication, Cell culture, Viral infection, Vero cell, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac75753ea6cfdc1e6711e570eefe016eTest
https://pubmed.ncbi.nlm.nih.gov/33767183Test

3

Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth

المؤلفون: David B. Shackelford, Steven D. Mittelman, Ernst W. Schmid, Peter J. Mullen, Milica Momcilovic, Simon R.V. Knott, Abigail S. Krall, Apisadaporn Thambundit, Heather R. Christofk, Felicia Surjono, Costas A. Lyssiotis, Christopher J. Halbrook

المصدر: Cell metabolism, vol 33, iss 5

مصطلحات موضوعية: 0301 basic medicine, Physiology, cancer metabolism, mTORC1, Medical Biochemistry and Metabolomics, Mice, chemistry.chemical_compound, 0302 clinical medicine, Mice, Inbred NOD, Neoplasms, Asparagine, Cancer, Tumor, Nucleotides, Chemistry, asparagine, Metformin, Mitochondria, Survival Rate, Biochemistry, Intracellular, Asparaginase, Context (language use), Mechanistic Target of Rapamycin Complex 1, cancer treatment, Cell Line, Endocrinology & Metabolism, 03 medical and health sciences, Cell Line, Tumor, Respiration, Animals, Humans, Molecular Biology, Cell Proliferation, Aspartic Acid, Cell growth, ATF4, dietary restriction, Cell Biology, asparaginase, Activating Transcription Factor 4, Diet, 030104 developmental biology, Electron Transport Chain Complex Proteins, Inbred NOD, Biochemistry and Cell Biology, respiration, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ff698e1ed01342f983891c97c95357Test
https://doi.org/10.1016Test/j.cmet.2021.02.001

4

The interplay between cell signalling and the mevalonate pathway in cancer

المؤلفون: Peter J. Mullen, Rosemary Yu, Michael C. Archer, Joseph Longo, Linda Z. Penn

المصدر: Nature Reviews Cancer. 16:718-731

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44579fb2e893e634174ba9ab66ffe337Test
https://doi.org/10.1038/nrc.2016.76Test

5

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

المؤلفون: William J. Sullivan, Milica Momcilovic, Daniel Braas, Utpal Banerjee, Andrew E. Whiteley, Ernst W. Schmid, David Jelinek, William E. Lowry, Peter J. Mullen, Matthew B. Maxwell, Mark S. Sharpley, Hilary A. Coller, Donald E. Ayer, David B. Shackelford, Thomas Q. de Aguiar Vallim, Blake R. Wilde, Aimee Flores, Heather R. Christofk

المصدر: Cell, vol 175, iss 1

مصطلحات موضوعية: 0301 basic medicine, cell migration, extracellular matrix, glucose metabolism, 1.1 Normal biological development and functioning, Hyaluronoglucosaminidase, hyaluronidase, Biology, Medical and Health Sciences, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, receptor tyrosine kinase signaling, Extracellular matrix, 03 medical and health sciences, Tristetraprolin, Underpinning research, Cell Line, Tumor, cell biology, Humans, Glycolysis, Hyaluronic Acid, ZFP36, Cancer, Glucose Transporter Type 1, Tumor, Glucose transporter, Cell migration, Biological Sciences, Cell biology, Extracellular Matrix, 030104 developmental biology, Glucose, GLUT1 trafficking, mRNA degradation, biology.protein, Intercellular Signaling Peptides and Proteins, Carbohydrate Metabolism, GLUT1, Signal transduction, Carrier Proteins, TXNIP, Signal Transduction, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c96199e1b89ffdcbcc9314a9aa530bTest
https://escholarship.org/uc/item/3x99h8gqTest

6

MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis

المؤلفون: Peter J. Mullen, Ahmed Aman, Linda Z. Penn, Benjamin Haibe-Kains, Aaliya Tamachi, Wail Ba-alawi, Rima Al-awar, David W. Cescon, Cornelia Redel, Cheryl H. Arrowsmith, Yu-Jia Shiah, Dharmendra Dingar, Brian Raught, William B. Tu, Corey Lourenco, Paul C. Boutros

المصدر: Cancer cell. 34(4)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f0fd34332be5f88813a6d939006c6aTest
https://pubmed.ncbi.nlm.nih.gov/30367118Test

7

Susceptibility to simvastatin-induced toxicity is partly determined by mitochondrial respiration and phosphorylation state of Akt

المؤلفون: Peter J. Mullen, Karin Brecht, Swarna Maseneni, Stephan Krähenbühl, Andrea Felser, Anja Zahno, Peter W. Lindinger

المصدر: Biochimica et biophysica acta

مصطلحات موضوعية: Simvastatin, Blotting, Western, Cell Respiration, Muscle Fibers, Skeletal, Muscle Proteins, Apoptosis, Mitochondrion, Biology, Real-Time Polymerase Chain Reaction, Mice, 03 medical and health sciences, Oxygen Consumption, 0302 clinical medicine, Geranylgeranylation, medicine, Animals, Humans, Myocyte, RNA, Messenger, Insulin-Like Growth Factor I, Phosphorylation, Molecular Biology, Protein kinase B, Cells, Cultured, 030304 developmental biology, Membrane Potential, Mitochondrial, Rap1, 0303 health sciences, SKP Cullin F-Box Protein Ligases, Toxicity, Reverse Transcriptase Polymerase Chain Reaction, Myogenesis, Anticholesteremic Agents, Akt, rap1 GTP-Binding Proteins, Statin, Skeletal muscle, Hep G2 Cells, Cell Biology, Mitochondria, 3. Good health, Cell biology, medicine.anatomical_structure, Signal transduction, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8ad8c0d17ed95ea7909a7cab539b08Test
https://doi.org/10.1016Test/j.bbamcr.2011.07.019

8

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

المصدر: Blood. 125(13)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee918c50a81b0e83f998a978a4aa41b5Test
https://pubmed.ncbi.nlm.nih.gov/25631767Test

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