نتائج البحث - "Sebastian Bauer"

1

Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies

المؤلفون: Stephane Ferretti, Sébastien Jeay, Ensar Halilovic, Claire Fabre, Laurence Van Bree, Christophe Meille, Jens Wuerthner, Florence Hourcade-Potelleret, Sebastian Bauer, Reinhard Dummer, Philippe A. Cassier, Astrid Jullion, George D. Demetri, Nelson Guerreiro, Daniel Shao-Weng Tan

المساهمون: University of Zurich, Bauer, Sebastian

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, Oncology, Cancer Research, Medizin, Administration, Oral, Piperazines, Mice, 0302 clinical medicine, Neoplasms, Medicine, 1306 Cancer Research, Drug Dosage Calculations, Platelet, 0303 health sciences, Drug discovery, Pharmacokinetic pharmacodynamic, 10177 Dermatology Clinic, Middle Aged, Treatment Outcome, Tolerability, 030220 oncology & carcinogenesis, Toxicity, Biomarker (medicine), 2730 Oncology, Female, Adult, medicine.medical_specialty, Growth Differentiation Factor 15, Cell Survival, 610 Medicine & health, Drug development, Article, Drug Administration Schedule, 03 medical and health sciences, In vivo, Cell Line, Tumor, Internal medicine, Biomarkers, Tumor, Animals, Humans, Dosing, Aged, Cell Proliferation, 030304 developmental biology, business.industry, Isoquinolines, Xenograft Model Antitumor Assays, Regimen, business

وصف الملف: 918_Bauer_S._et_al._Pharmacokinetic-pharmacodynamic_guided_optimisation_of_dose_and_schedule_of_CGM097,_an_HDM2_inhibitor_Br_J_Cancer_2021.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962edae56c80ae45d9537101a31228f2Test
https://doi.org/10.1038/s41416-021-01444-4Test

2

3D-bioprinting of aortic valve interstitial cells: impact of hydrogel and printing parameters on cell viability

المؤلفون: Moritz Benjamin Immohr, Fabió Dos Santos Adrego, Helena Lauren Teichert, Vera Schmidt, Yukiharu Sugimura, Sebastian Bauer, Mareike Barth, Artur Lichtenberg, Payam Akhyari

المصدر: Biomedical Materials. 18:015004

مصطلحات موضوعية: Sheep, Tissue Engineering, Tissue Scaffolds, Cell Survival, Bioprinting, Biomedical Engineering, Calcinosis, Hydrogels, Bioengineering, Aortic Valve Stenosis, Biomaterials, Aortic Valve, Printing, Three-Dimensional, Animals, Gelatin, Cells, Cultured

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6e8ac822ee0680ea2c1da53060c950Test
https://doi.org/10.1088/1748-605x/ac9f91Test

3

Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

المؤلفون: Suzanne George, Jonathan A. Fletcher, George D. Demetri, Chandrajit P. Raut, César Serrano, Channing Yu, Jeffrey T. Czaplinski, Meijun Zhu, Ajia Presnell, Grant Eilers, Julia Ketzer, Michael Heinrich, Sebastian Bauer, Adrián Mariño-Enríquez, Ewa Sicinska, Derrick Tao, Arin McKinley, Brian P. Rubin, Aristotle M. Mannan

المساهمون: Institut Català de la Salut, [Serrano C] Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Sarcoma Translational Research Laboratory, Vall d’Hebron Institute of Oncology, Barcelona, Spain. Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Mariño-Enríquez A, Tao DL, Eilers G, Zhu M] Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA. [Ketzer J] Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus

المصدر: British Journal of Cancer
Scientia
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname

مصطلحات موضوعية: Cancer Research, Pyridines, Medizin, Other subheadings::Other subheadings::/drug therapy [Other subheadings], Imatinib resistant, Medicaments antineoplàstics, Mice, 0302 clinical medicine, Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms [DISEASES], Sunitinib, Gastrointestinal Neoplasms, Sarcoma, Gastrointestinal stromal tumours, 3. Good health, Tracte gastrointestinal - Càncer, Proto-Oncogene Proteins c-kit, Oncology, 030220 oncology & carcinogenesis, Imatinib Mesylate, Female, Tyrosine kinase, medicine.medical_specialty, Physiological Phenomena::Pharmacological and Toxicological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance, Neoplasm [PHENOMENA AND PROCESSES], Gastrointestinal Stromal Tumors, Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores], Mice, Nude, CHO Cells, Predictive markers, Article, 03 medical and health sciences, Clinical Trials, Phase II as Topic, Cricetulus, neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales [ENFERMEDADES], medicine, Animals, Humans, neoplasms, Protein Kinase Inhibitors, Resistència als medicaments, fenómenos fisiológicos::fenómenos farmacológicos y toxicológicos::fenómenos farmacológicos::resistencia a medicamentos::resistencia a los antineoplásicos [FENÓMENOS Y PROCESOS], Competing interests, business.industry, Extramural, Phenylurea Compounds, Correction, Xenograft Model Antitumor Assays, digestive system diseases, Drug Resistance, Neoplasm, Family medicine, Mutation, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10174f3c4da5888b2765f3b74049e79Test
https://doi.org/10.1038/s41416-019-0389-6Test

4

Cenobamate for the treatment of focal epilepsies

المؤلفون: Catrin Mann, Sebastian Bauer, Laurent M. Willems, Felix Rosenow, Adam Strzelczyk

المصدر: Expert opinion on pharmacotherapy. 21(18)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce28f320f1636e68b6681daaa542f84aTest
https://pubmed.ncbi.nlm.nih.gov/32812825Test

5

Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy

المصدر: Neurobiology of Disease, Vol 144, Iss, Pp 105048-(2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e169184f3937adac56d23d9a3560e3abTest
https://pubmed.ncbi.nlm.nih.gov/32800995Test

6

Prophylactic Antiviral Activity of Sulfated Glycomimetic Oligomers and Polymers

المؤلفون: Miriam Becker, Kevin Janus, Markus Giesler, Laura Hartmann, Patrick Pierzyna, Laura Soria-Martinez, Sebastian Bauer, Sonja Schelhaas, Mario Schelhaas, Jennifer Materlik, Nicole L. Snyder

المصدر: Journal of the American Chemical Society. 142(11)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb737e91a102c3637b8a209d48683feTest
https://pubmed.ncbi.nlm.nih.gov/32105452Test

7

Preclinical models for translational sarcoma research

المؤلفون: Sebastian Bauer, Rainer Hamacher

المصدر: Current Opinion in Oncology. 29:275-285

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724012199708777b9a717473e4435a48Test
https://doi.org/10.1097/cco.0000000000000373Test

8

A microRNA‐129‐5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses

المصدر: Rajman, M, Metge, F, Fiore, R, Khudayberdiev, S, Aksoy-Aksel, A, Bicker, S, Reschke, C R, Raoof, R, Brennan, G P, Delanty, N, Farrell, M A, O'Brien, D F, Bauer, S, Norwood, B, Veno, M T, Krueger, M, Braun, T, Kjems, J, Rosenow, F, Henshall, D C, Dieterich, C & Schratt, G 2017, ' A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses ', E M B O Journal, vol. 36, no. 12, pp. 1770-1787 . https://doi.org/10.15252/embj.201695748Test

مصطلحات موضوعية: Doublecortin Domain Proteins, 0301 basic medicine, Proteome, MICRORNAS, RNA-binding protein, Bioinformatics, Hippocampus, Epileptogenesis, Mice, SYNAPTIC PLASTICITY, Homeostatic plasticity, Picrotoxin, Synaptic scaling, microRNA, biology, General Neuroscience, Articles, Crosstalk (biology), Excitatory postsynaptic potential, RNA Splicing Factors, Microtubule-Associated Proteins, EXPRESSION, Doublecortin Protein, PROTEINS, AMPA receptor, General Biochemistry, Genetics and Molecular Biology, homeostatic plasticity, Plasma Membrane Calcium-Transporting ATPases, 03 medical and health sciences, Animals, synaptic scaling, VISUAL-CORTEX, Molecular Biology, General Immunology and Microbiology, AMPA RECEPTORS, Gene Expression Profiling, Neuropeptides, STATUS EPILEPTICUS, Computational Biology, MAMMALIAN BRAIN, Doublecortin, MicroRNAs, 030104 developmental biology, Gene Expression Regulation, MESSENGER-RNA LOCALIZATION, Synapses, Synaptic plasticity, biology.protein, epilepsy, DENDRITIC SPINE DEVELOPMENT, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fb481b7f9a93f21613c2cc0cffbd33Test
https://doi.org/10.15252/embj.201695748Test

9

Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors

المؤلفون: Seongju Yun, Cheol Keun Park, Min Goo Lee, Won Kyu Kim, Hoguen Kim, Jiyoon Kim, Sebastian Bauer

المصدر: Clinical Cancer Research. 23:845-856

مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Cancer Research, Pathology, medicine.medical_specialty, Stromal cell, Gastrointestinal Stromal Tumors, Mutant, Medizin, Golgi Apparatus, Kaplan-Meier Estimate, Biology, Endoplasmic Reticulum, medicine.disease_cause, Disease-Free Survival, Cell Line, 03 medical and health sciences, symbols.namesake, medicine, Animals, Humans, RNA, Small Interfering, Protein kinase C, Gastrointestinal Neoplasms, GiST, Endoplasmic reticulum, Transfection, Golgi apparatus, Neoplasm Proteins, Enzyme Activation, Gene Expression Regulation, Neoplastic, Proto-Oncogene Proteins c-kit, 030104 developmental biology, Oncology, Protein Kinase C-theta, Mutation, Proteolysis, symbols, Cancer research, RNA Interference, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81d36bbd1615bf4fa68fba5828dc1dfTest
https://doi.org/10.1158/1078-0432.ccr-16-0521Test

10

Laser microdissection-based microproteomics of the hippocampus of a rat epilepsy model reveals regional differences in protein abundances

المؤلفون: Barbara Henning, Alexandre Hilário Berenguer de Matos, Braxton A. Norwood, Fernando Cendes, Rovilson Gilioli, Felix Rosenow, Sebastian Bauer, André Schwambach Vieira, Iscia Lopes-Cendes, Amanda Morato do Canto, Benilton S. Carvalho

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1255b66b5c13e04aa8ed1d32454c0fd5Test
https://pubmed.ncbi.nlm.nih.gov/32157145Test

تنقيح النتائج