An efficient numerical tool for dose deposition prediction applied to synchrotron medical imaging and radiation therapy
| العنوان: | An efficient numerical tool for dose deposition prediction applied to synchrotron medical imaging and radiation therapy |
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| المؤلفون: | Emmanuel Brun, Nicolas Freud, Sergei Gasilov, David Sarrut, François Smekens, Claudio Ferrero, Jean Michel Létang, Alberto Mittone, Fabien Baldacci, François Delaire, Paola Coan, Alberto Bravin |
| المساهمون: | European Synchrotron Radiation Facility (ESRF), Imagerie Tomographique et Radiothérapie, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Faculty of Medicine, Ludwig-Maximilians-Universität München (LMU), Faculty of Physics, Mittone, A, Baldacci, F, Bravin, A, Brun, E, Delaire, F, Ferrero, C, Gasilov, S, Freud, N, Letang Jean, M, Sarrut, D, Smekens, F, Coan, P |
| المصدر: | Journal of Synchrotron Radiation Journal of Synchrotron Radiation, International Union of Crystallography, 2013, 20 (5), pp.785-92. ⟨10.1107/S0909049513017184⟩ |
| بيانات النشر: | International Union of Crystallography (IUCr), 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Diagnostic Imaging, Nuclear and High Energy Physics, medicine.medical_specialty, Knee Joint, Monte Carlo method, FIS/07 - FISICA APPLICATA (A BENI CULTURALI, AMBIENTALI, BIOLOGIA E MEDICINA), Synchrotron radiation, Radiation Dosage, 030218 nuclear medicine & medical imaging, law.invention, X-ray, 03 medical and health sciences, 0302 clinical medicine, law, Geant4/GATE, medicine, Medical imaging, Humans, Medical physics, Monte Carlo, Instrumentation, Physics, fast dose simulation, Radiation, Experimental data, Estimator, Radiotherapy Dosage, Gold standard (test), Radiotherapy, Computer-Assisted, Synchrotron, 3. Good health, Radiography, Orders of magnitude (time), 030220 oncology & carcinogenesis, Female, Ultrasonography, Mammary, Monte Carlo Method, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, Algorithm, Synchrotrons |
| الوصف: | Medical imaging and radiation therapy are widely used synchrotron-based techniques which have one thing in common: a significant dose delivery to typically biological samples. Among the ways to provide the experimenters with image guidance techniques indicating optimization strategies, Monte Carlo simulation has become the gold standard for accurately predicting radiation dose levels under specific irradiation conditions. A highly important hampering factor of this method is, however, its slow statistical convergence. A track length estimator (TLE) module has been coded and implemented for the first time in the open-source Monte Carlo codeGATE/Geant4. Results obtained with the module and the procedures used to validate them are presented. A database of energy-absorption coefficients was also generated, which is used by the TLE calculations and is now also included inGATE/Geant4. The validation was carried out by comparing the TLE-simulated doses with experimental data in a synchrotron radiation computed tomography experiment. The TLE technique shows good agreementversusboth experimental measurements and the results of a classical Monte Carlo simulation. Compared with the latter, it is possible to reach a pre-defined statistical uncertainty in about two to three orders of magnitude less time for complex geometries without loss of accuracy. |
| تدمد: | 0909-0495 1600-5775 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b03cb7d7ba87199dd988895c0cf66cTest https://doi.org/10.1107/s0909049513017184Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....80b03cb7d7ba87199dd988895c0cf66c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09090495 16005775 |
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