Systemic sclerosis and its pulmonary complications in The Netherlands: an epidemiological study
| العنوان: | Systemic sclerosis and its pulmonary complications in The Netherlands: an epidemiological study |
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| المؤلفون: | Evelien Ton, Repke J. Snijder, P L A van Daele, Madelon C. Vonk, Hendrika Bootsma, F.H.J. van den Hoogen, P Th W van Hal, A.P.J. van Dijk, Yvonne F. Heijdra, B Broers, J.M. van Laar |
| المساهمون: | Translational Immunology Groningen (TRIGR), Immunology, Pulmonary Medicine, Internal Medicine |
| المصدر: | Annals of the Rheumatic Diseases, 68, 6, pp. 961-5 Annals of the Rheumatic Diseases, 68(6), 961-965. BMJ PUBLISHING GROUP Annals of the Rheumatic Diseases, 68(6), 961-965. BMJ Publishing Group Annals of the Rheumatic Diseases, 68, 961-5 |
| بيانات النشر: | BMJ Publishing Group, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Male, LUNG-DISEASE, Pulmonary Fibrosis, Prevalence, Placebo-controlled study, MULTICENTER, PLACEBO-CONTROLLED TRIAL, THERAPY, Scleroderma, DOUBLE-BLIND, Surveys and Questionnaires, SCLERODERMA, Epidemiology, Pulmonary fibrosis, CYCLOPHOSPHAMIDE, Immunology and Allergy, FIBROSIS, Registries, skin and connective tissue diseases, Lung, Netherlands, Aged, 80 and over, Cardiovascular diseases [NCEBP 14], integumentary system, Incidence (epidemiology), Incidence, Interstitial lung disease, Middle Aged, PREVALENCE, Pathogenesis and modulation of inflammation [N4i 1], Female, Adult, medicine.medical_specialty, Adolescent, Hypertension, Pulmonary, Immunology, Auto-immunity, transplantation and immunotherapy [N4i 4], General Biochemistry, Genetics and Molecular Biology, Young Adult, Age Distribution, Rheumatology, Internal medicine, medicine, Humans, Sex Distribution, Aged, Scleroderma, Systemic, business.industry, Total Lung Capacity, medicine.disease, Pulmonary hypertension, Surgery, Evaluation of complex medical interventions [NCEBP 2], ARTERIAL-HYPERTENSION, business, Epidemiologic Methods |
| الوصف: | Contains fulltext : 81439.pdf (Publisher’s version ) (Closed access) The prevalence and incidence of systemic sclerosis (SSc) in The Netherlands is unknown. The same holds true for its leading causes of death: pulmonary fibrosis and pulmonary arterial hypertension (PAH), for which effective treatment options have recently become available. OBJECTIVE: To establish the prevalence and incidence of SSc and its pulmonary complications. METHODS: Detailed information on patients in the POEMAS registry, "Pulmonary Hypertension Screening, a Multidisciplinary Approach in Scleroderma", consisting of 819 patients, was combined with a nationwide questionnaire. RESULTS: By combining the two sources the prevalence of SSc was found to be 8.9 per 100 000 adults. The incidence was 0.77 patients per 100 000 per year. PAH was diagnosed in 9.9% of SSc patients. The prevalence of interstitial lung disease in SSc varied from 19% to 47% depending on the definition used. CONCLUSION: This study clarifies the epidemiology of SSc in The Netherlands and confirms the frequent occurrence of pulmonary complications, based on 654 cases. This can and will be studied further in the ongoing POEMAS study. |
| وصف الملف: | application/pdf |
| تدمد: | 1468-2060 0003-4967 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d6eac2779466448e071ce8b44f926dTest https://pure.eur.nl/en/publications/58e7d037-2555-490b-bfb8-2dee324b48c5Test |
| حقوق: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....20d6eac2779466448e071ce8b44f926d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14682060 00034967 |
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