المؤلفون: Umay Balci, Ayşegül Seremet Keskin, Kübra Demir Önder

المصدر: Mediterranean Journal of Infection, Microbes and Antimicrobials, Vol 10, Iss 1 (2021)

مصطلحات موضوعية: Microbiology (medical), medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Hospitalized patients, Lymphocyte, Infectious and parasitic diseases, RC109-216, Gastroenterology, chemistry.chemical_compound, Lactate dehydrogenase, Internal medicine, medicine, Interleukin 6, General Immunology and Microbiology, biology, business.industry, interleukin-6, lactate dehydrogenase/lymphocyte, Infectious Diseases, medicine.anatomical_structure, chemistry, covid-19, biology.protein, Medicine, business, Value (mathematics)

الوصف: Introduction: Clinical picture of Coronavirus disease-2019 (COVID-19) ranges from mild respiratory symptoms to severe respiratory failure and death. To determine the severity of the disease; lymphocyte count, lactate dehydrogenase (LDH), C-reactive protein (CRP), D-dimer and interleukin-6 (IL-6) levels are the parameters that are used. In this study, it was aimed to evaluate effect of LDH/lymphocyte ratio on prognosis and whether there was a correlation between LDH/lymphocyte ratio and IL-6 in hospitalized patients with COVID-19. Materials and Methods: Patients who were aged 18 years and older, were positive for Severe acute respiratory syndrome-Coronavirus-2 polymerase chain reaction test, had COVID-19 pneumonia findings on tomography, and hospitalized for at least three days were included in the study. Results: The mean age of the patients was 59.35±15.23 year and 56 (59.6%) of patients were male. Fifty seven (60.6%) of the patients had comorbid diseases. The 14- and 28-day mortality rates were 14.9% and 27.7%, respectively. There was a statistically significant correlation between hospitalization in intensive care unit and LDH, lymphocyte count, LDH/lymphocyte ratio, CRP, highest D-dimer, initial IL-6, neutrophil/lymphocyte ratio, and highest IL-6 values (p

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2400d08fe5d3c11a4745bcb9e5187f4eTest
http://mjima.org/abstract.php?id=285Test

المؤلفون: Ulas Aday, Hasan Akkoc, Abdullah Böyük

المساهمون: Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı, Aday, Ulaş

المصدر: Annals of Surgical Treatment and Research

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Multivariate analysis, Survival, Colorectal cancer, Gastroenterology, Colorectal neoplasms, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Lactate dehydrogenase-to-albumin ratio, medicine, Receiver operating characteristic, Proportional hazards model, business.industry, Cancer, Retrospective cohort study, Odds ratio, medicine.disease, Confidence interval, 030104 developmental biology, 030220 oncology & carcinogenesis, Original Article, Surgery, business

الوصف: WOS:000567477200005 PMID: 32908848 Purpose: The purpose of our study was initially to explore the prognostic role of LDH-to-albumin ratio in patients with colorectal carcinoma (CRC) undergoing curative resection. Methods: The retrospective study included 295 CRC patients that underwent curative resection. According to time-dependent receiver operating characteristics (ROC) analysis, the optimal cutoff value for pretreatment LDH-to-albumin ratio was 52.7. Cox regression univariate and multivariate analyses were utilized to analyze the prognostic factors for disease-free survival (DFS) and overall survival (OS). Results: The 295 participants included 117 women (39.7%) and had an overall mean age of 55.8 ± 14.1 years. The median follow-up period was 31.8 ± 21 months (range, 6-78 months) and 53 patients (18.0%) died from cancer during the followup period. The 5-year DFS and OS rates were 65.4% and 68.5% in patients with LDH-to-albumin ratio

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ebaaae1321308602822bf4b367f8e9Test
https://hdl.handle.net/11468/7161Test

المؤلفون: Muhammet Gülhan, Erol Şentürk, Pınar Yıldız Gülhan, Oya Yildiz, Hüsnü Baykal

المصدر: Volume: 20, Issue: 1 21-22
Duzce Medical Journal

مصطلحات موضوعية: COPD, Systemic disease, medicine.medical_specialty, business.industry, Pleural effusion, Interstitial lung disease, Rheumatoid nodule, General Medicine, Disease, respiratory system, medicine.disease, Gastroenterology, respiratory tract diseases, chemistry.chemical_compound, chemistry, Health Care Sciences and Services, Rheumatoid arthritis, Lactate dehydrogenase, Internal medicine, COPD,pleural effusion,rheumatoid arthritis, medicine, KOAH,plevral sıvı,romatoid artrit, medicine.symptom, Sağlık Bilimleri ve Hizmetleri, business

الوصف: Rheumatoid arthritis (RA) is a systemic disease with symmetrical, polyarticular joint involvement. In patients with RA, pleural effusion usually occurs a few years after the onset of the disease and is often considered as a disease exacerbation. RA may cause pleural effusion, interstitial lung disease, pleuritis, airway disease and rheumatoid nodule in the lungs. Aseptic exudative pleural effusions with low pH, low glucose and high lactate dehydrogenase (LDH) values might be seen in RA. Diagnosis is usually made by exclusion of other pleural fluid causes. In this study, a 52-year-old patient who was diagnosed as RA 6 months ago and treated irregularly was presented to emphasize that pleural effusion may develop in patients with irregular RA. The patient had previously undiagnosed chronic obstructive pulmonary disease (COPD) and the patient’s COPD treatment was also regulated. It should not be forgotten that pleural effusion may develop among RA patients with irregular treatment.
Romatoid artrit (RA) simetrik, poliartiküler eklem tutulumu olan sistemik bir hastalıktır. RA’lı hastalarda plevral efüzyon genellikle hastalık başladıktan bir kaç yıl sonra ortaya çıkar ve sıklıkla hastalık alevlenmesi olarak kabul edilir. RA akciğer tutulumu olarak; plevral efüzyon, plörit, hava yolu hastalığı, romatoid nodül ve intertisyel akciğer hastalığı görülür. Plevral sıvı aseptik eksuda karakterindedir ve sıvıda düşük pH, düşük glukoz ve yüksek laktat dehidrogenaz (LDH) değerleri görülür. Tanı genellikle diğer plevral sıvı nedenlerinin dışlanması sonucu konulur. Bu çalışmada, 6 ay önce RA tanısı konan ve düzensiz tedavi alan 52 yaşındaki hasta, düzensiz RA tedavisi alan hastalarda plevral sıvı gelişebileceğini vurgulamak amacıyla sunulmuştur. Hastada daha önce tanı konulmamış kronik obstruktif akciğer hastalığı (KOAH) mevcuttu ve hastanın KOAH tedavisi de düzenlendi. Düzensiz RA tedavisi alan olgularda RA’ya bağlı olarak plevral efüzyon gelişebileceği unutulmamalıdır.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e3ef22b138804fc6ea8f1dbe9aa896Test
https://dergipark.org.tr/tr/pub/dtfd/issue/38727/423770Test