مراجعة
Philadelphia-like acute lymphoblastic leukemia in pediatric cases ; Pediatrik vakalarda philadelphia benzeri akut lenfoblastik lösemi
| العنوان: | Philadelphia-like acute lymphoblastic leukemia in pediatric cases ; Pediatrik vakalarda philadelphia benzeri akut lenfoblastik lösemi |
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| المساهمون: | Bursa Uludağ Üniversitesi/Tıp Fakültesi/ Tıbbi biyoloji Anabilim Dalı, Bursa Uludağ Üniversitesi/Tıp Fakültesi/ Çocuk Sağlığı Ve Hastalıkları Anabilim Dalı ve Onkoloji Bilim Dalı, orcid:0000-0002-0910-4258, Erdem, Ecem Efendi, Çeçener, Gülşah, Ünlü, Havva Tezcan, Evim, Melike Sezgin, GYU-0252-2022, ESY-2704-2022, AAP-9988-2020, AAH-1452-2021, 57223043925, 6508156530, 57223050102, 36337796600 |
| بيانات النشر: | Galenos Yayıncılık |
| سنة النشر: | 2021 |
| المجموعة: | Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
| مصطلحات موضوعية: | Philadelphia-like, Acute lymphoblastic leukemia, Pediatric, Progress, Chıldren, Pediatrics, Philadelphia 1 Chromosome, BCR ABL protein, Olanzapine, Thymic stromal lymphopoietin, Adult, Burkitt lymphoma, Cancer prognosis, Case report, Chemiluminescence, Immunoassay, Child, Clinical article, Clinical evaluation, Controlled study, Flow cytometry, Fluorescence in situ, Hybridization, Gene expression profiling, Gene mutation, Health care personnel, Heart ejection fraction, Hematopoietic cell, Human, Human cell |
| الوصف: | Leukemia is a heterogeneous group of neoplastic diseases that develop as a result of the malignant transformation of hematopoietic cells. Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a subgroup of B-cell acute lymphoblastic leukemia (B-ALL), which is included in the high-risk classification and has a poor prognosis. It is similar to Ph-positive ALL in gene expression profile, but this subtype does not have BCR-ABL1 fusion. The disease is genetically heterogeneous. In addition, the genetic changes of Ph-like ALL cases with different ethnic origins also differ. It is important to distinguish and classify Ph-like ALL cases from patients with B-ALL for effective treatment. In recent years, it is on the agenda to design panels in which gene expression differences are analyzed in addition to evaluating genetic and clinical findings in B-ALL cases to identify cases belonging to the Ph-like ALL subgroup. |
| نوع الوثيقة: | review |
| اللغة: | Turkish |
| تدمد: | 1304-9054 1308-6308 |
| العلاقة: | Makale - Uluslararası Hakemli Dergi; Guncel Pediatri; Yurt içi; Erdem, E. E. vd. (2021) "Philadelphia-like acute lymphoblastic leukemia in pediatric cases". Güncel Pediatri, 19(1), 141-150.; https://doi.org/10.4274/jcp.2020.0020Test; https://cms.galenos.com.tr/Uploads/Article_48534/G%C3%BCncel%20Pediatri-18-220-En.pdfTest; https://hdl.handle.net/11452/39052Test; 000735332200020; 2-s2.0-85104633068; 141; 150; 19 |
| DOI: | 10.4274/jcp.2020.0020 |
| الإتاحة: | https://doi.org/10.4274/jcp.2020.0020Test https://hdl.handle.net/11452/39052Test https://cms.galenos.com.tr/Uploads/Article_48534/G%C3%BCncel%20Pediatri-18-220-En.pdfTest |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.15E67147 |
| قاعدة البيانات: | BASE |
| تدمد: | 13049054 13086308 |
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| DOI: | 10.4274/jcp.2020.0020 |