دورية أكاديمية
أعرض في EDS

Epstein-Barr virus infection of infants: implications of early age of infection on viral control and risk for Burkitt lymphoma

التفاصيل البيبلوغرافية
العنوان: Epstein-Barr virus infection of infants: implications of early age of infection on viral control and risk for Burkitt lymphoma
المؤلفون: Rosemary Rochford
المصدر: Boletín Médico del Hospital Infantil de México, Vol 73, Iss 1, Pp 41-46 (2016)
بيانات النشر: Permanyer, 2016.
سنة النشر: 2016
المجموعة: LCC:Pediatrics
LCC:Public aspects of medicine
مصطلحات موضوعية: Epstein-Barr virus, Burkitt lymphoma, Plasmodium falciparum, Malaria, Activation induced cytidine deaminase, Pediatrics, RJ1-570, Public aspects of medicine, RA1-1270
الوصف: Since its first description by Denis Burkitt, endemic Burkitt's lymphoma (BL), the most common childhood cancer in sub-Saharan Africa, has led scientists to search for clues to the origins of this malignancy. The discovery of Epstein-Barr virus (EBV) in BL cells over 50 years ago led to extensive sero-epidemiology studies and revealed that rather than being a virus restricted to areas where BL is endemic, EBV is ubiquitous in the world's population with an estimated greater than 90% of adults worldwide infected. A second pathogen, Plasmodium falciparum (P. falciparum) malaria is also linked to BL. In this review, we will discuss recent studies that indicate a role for P. falciparum malaria in dysregulating EBV infection, and increasing the risk for BL in children living where P. falciparum malaria transmission is high.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Spanish; Castilian
تدمد: 1665-1146
العلاقة: http://www.sciencedirect.com/science/article/pii/S1665114615002385Test; https://doaj.org/toc/1665-1146Test
DOI: 10.1016/j.bmhimx.2015.12.001
الوصول الحر: https://doaj.org/article/00cff61a4f554923853381249b7392e4Test
رقم الانضمام: edsdoj.00cff61a4f554923853381249b7392e4
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16651146
DOI:10.1016/j.bmhimx.2015.12.001