كتاب
Coherent silicon photonic interferometric biosensor with an inexpensive laser source for sensitive label-free immunoassays
| العنوان: | Coherent silicon photonic interferometric biosensor with an inexpensive laser source for sensitive label-free immunoassays |
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| المؤلفون: | Leuermann, Jonas, Stamenkovic, Vladimir, Ramirez-Priego, Patricia, Sánchez-Postigo, Alejandro, Fernández-Gavela, Adrián, Chapman, Cole A., Bailey, Ryan C., Lechuga, Laura M., Perez-Inestrosa, Ezequiel, Collado, Daniel, Halir, Robert, Molina-Fernández, Íñigo |
| المساهمون: | Leuermann,J, Stamenkovic,V, Perez-Inestrosa,E, Collado,D, Halir,R, Molina-Fernández,Í Bionand Center for Nanomedicine and Biotechnology, Málaga, Spain. Leuermann,J, Sánchez-Postigo,A, Molina-Fernández,Í Departamento de Ingeniería de Comunicaciones, University of Málaga, ETSI Telecomunicación, Málaga, Spain. Stamenkovic,V, Collado,D Departamento de Química Orgánica, Facultad de Ciencias, University of Málaga, Málaga, Spain. Ramirez-Priego,P, Lechuga,LM Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, BIST and CIBER-BBN Campus UAB, Barcelona, Spain. Fernández-Gavela,A Departamento de Física, Universidad de Oviedo, Oviedo, Spain. Chapman,CA, Bailey,RC Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Horizon 2020 Framework Programme (EuroNanoMed 3-H2020 DrNanoDAII), Ministerio de Economía y Competitividad (2019/PCI 2019-2, CTQ2017-86994-R, SEV-2017-0706), Junta de Andalucía, Proyectos Excelencia-Retos (P18-RT-1453, P18-RT-793), Fondos Europeos de Desarrollo Regional (CTQ2016-75870-P, PID2019-104293GB-I00, RD16/0006/0012, TEC2016-80718-R, UMA18-FEDERJA-007, UMA18-FEDERJA-219), H2020 Marie Skłodowska-Curie Actions (713721). |
| بيانات النشر: | Optical Society of America |
| سنة النشر: | 2020 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | Photons, Fotones, Biosensing techniques, Técnicas biosensibles, Lasers, Rayos laser, Interferometry, Interferometría, C-Reactive Protein, Proteína C-Reactiva, Limit of detection, Límite de detección, Immunoassay, Inmunoensayo, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Optical Phenomena::Light::Photons, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Molecular Probe Techniques::Biosensing Techniques, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Optical Devices::Lasers, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Interferometry, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Albumins::C-Reactive Protein, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunoassay |
| الوصف: | Over the past two decades, integrated photonic sensors have been of major interest to the optical biosensor community due to their capability to detect low concentrations of molecules with label-free operation. Among these, interferometric sensors can be read-out with simple, fixed-wavelength laser sources and offer excellent detection limits but can suffer from sensitivity fading when not tuned to their quadrature point. Recently, coherently detected sensors were demonstrated as an attractive alternative to overcome this limitation. Here we show, for the first time, to the best of our knowledge, that this coherent scheme provides sub-nanogram per milliliter limits of detection in C-reactive protein immunoassays and that quasi-balanced optical arm lengths enable operation with inexpensive Fabry-Perot-type lasers sources at telecom wavelengths. ; Yes |
| نوع الوثيقة: | manuscript |
| وصف الملف: | application/pdf |
| اللغة: | Spanish; Castilian |
| تدمد: | 0146-9592 1539-4794 |
| العلاقة: | https://www.osapublishing.org/ol/fulltext.cfm?uri=ol-45-24-6595&id=444310Test; Leuermann J, Stamenkovic V, Ramirez-Priego P, Sánchez-Postigo A, Fernández-Gavela A, Chapman CA, et al. Coherent silicon photonic interferometric biosensor with an inexpensive laser source for sensitive label-free immunoassays. Opt Lett. 2020 Dec 8;45(24):6595-6598.; http://hdl.handle.net/10668/3374Test |
| DOI: | 10.1364/OL.411635 |
| الإتاحة: | https://doi.org/10.1364/OL.411635Test http://hdl.handle.net/10668/3374Test |
| حقوق: | Acceso abierto |
| رقم الانضمام: | edsbas.8CA0F3AE |
| قاعدة البيانات: | BASE |
| تدمد: | 01469592 15394794 |
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| DOI: | 10.1364/OL.411635 |