نتائج البحث

المساهمون: Работа выполнена за счет средств бюджетного финансирования на выполнение государственного задания по теме «Изучение иммунопатологии, диагностики и терапии на ранних стадиях системных ревматических заболеваний» (регистрационный номер 1021051402790-6).

المصدر: Rheumatology Science and Practice; Vol 61, No 3 (2023); 339–348 ; Научно-практическая ревматология; Vol 61, No 3 (2023); 339–348 ; 1995-4492 ; 1995-4484

مصطلحات موضوعية: HOMA-IR, systemic lupus erythematosus, phenotypes, obesity, overweight, body mass index, leptin, hyperleptinemia, insulin resistance, системная красная волчанка, фенотипы, ожирение, избыточный вес, индекс массы тела, лептин, гиперлептинемия, инсулинорезистентность

وصف الملف: application/pdf

العلاقة: https://rsp.mediar-press.net/rsp/article/view/3361/2289Test; Myasoedova E, Crowson CS, Kremers HM, Roger VL, Fitz-Gibbon PD, Therneau TM, et al. Lipid paradox in rheumatoid arthritis: The impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease. Ann Rheum Dis. 2011;70(3):482-487. doi:10.1136/ard.2010.135871; Baker JF, Billig E, Michaud K, Ibrahim S, Caplan L, Cannon GW, et al. Weight loss, the obesity paradox, and the risk of death in rheumatoid arthritis. Arthritis Rheumatol. 2015;67(7):1711-1717. doi:10.1002/art.39136; Kremers HM, Nicola PJ, Crowson CS, Ballman KV, Gabriel SE. Prognostic importance of low body mass index in relation to cardiovascular mortality in rheumatoid arthritis. Arthritis Rheum. 2004;50(11):3450-3457. doi:10.1002/art.20612; Santos MJ, Vinagre F, Canas da Silva J, Gil V, Fonseca JE. Body composition phenotypes in systemic lupus erythematosus and rheumatoid arthritis: A comparative study of Caucasian female patients. Clin Exp Rheumatol. 2011;29(3):470-476.; Katz P, Gregorich S, Yazdany J, Trupin L, Julian L, Yelin E, et al. Obesity and its measurement in a community-based sample of women with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011;63(2):261-268. doi:10.1002/acr.20343; Elkan AC, Engvall IL, Cederholm T, Hafström I. Rheumatoid cachexia, central obesity and malnutrition in patients with lowactive rheumatoid arthritis: Feasibility of anthropometry, mini nutritional assessment and body composition techniques. Eur J Nutr. 2009;48(5):315-322. doi:10.1007/s00394-009-0017-y; Сорокина АО, Демин НВ, Добровольская ОВ, Никитинская ОА, Торопцова НВ, Феклистов АЮ. Патологические фенотипы состава тела у больных ревматическими заболеваниями. Научно-практическая ревматология. 2022;60(4):487-494. doi:10.47360/1995-4484-2022-487-494; Eckel N, Li Y, Kuxhaus O, Stefan N, Hu FB, Schulze MB. Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across BMI categories in 90 257 women (the Nurses’ Health Study): 30 year follow-up from a prospective cohort study. Lancet Diabetes Endocrinol. 2018;6(9):714-724. doi:10.1016/S2213-8587(18)30137-2; Kim NH, Kim KJ, Choi J, Kim SG. Metabolically unhealthy individuals, either with obesity or not, have a higher risk of critical co ronavirus disease 2019 outcomes than metabolically healthy individuals without obesity. Metabolism. 2022;128:154894. doi:10.1016/j.metabol.2021.154894; Stefan N. Metabolically healthy and unhealthy normal weight and obesity. Endocrinol Metab (Seoul). 2020;35(3):487-493. doi:10.3803/EnM.2020.301; Wildman RP, Muntner P, Reynolds K, McGinn AP, Rajpathak S, Wylie-Rosett J, et al. The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999–2004). Arch Intern Med. 2008;168(15):1617-1624. doi:10.1001/archinte.168.15.1617; Шляхто ЕВ, Недогода СВ, Конради АО, Баранова ЕИ, Фомин ВВ, Верткин АЛ, и др. Концепция новых национальных клинических рекомендаций по ожирению. Российский кардиологический журнал. 2016;(4):7-13. doi:10.15829/1560-4071-2016-4-7-13; Giraud C, Lambertc C, Dutheild F, Pereirac B, Soubriera M, Tournadre A. The relationship between weight status and metabolic syndrome in patients with rheumatoid arthritis and spondyloarthritis. Joint Bone Spine. 2021;88(1):105059. doi:10.1016/j.jbspin.2020.07.008; Frithioff-Bøjsøe C, Lund MAV, Lausten-Thomsen U, Hedley PL, Pedersen O, Christiansen M, et al. Leptin, adiponectin, and their ratio as markers of insulin resistance and cardiometabolic risk in childhood obesity. Pediatr Diabetes. 2020;21(2):194-202. doi:10.1111/pedi.12964; Bungau S, Behl T, Tit DM, Banica F, Bratu OG, Diaconu CC, et al. Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD. Exp Ther Med. 2020;20(6):197. doi:10.3892/etm.2020.9327; Katsiki N, Mikhailidis DP, Banach M. Leptin, cardiovascular diseases and type 2 diabetes mellitus. Acta Pharmacol Sin. 2018;39(7):1176-1188. doi:10.1038/aps.2018.40; Bell BB, Rahmouni K. Leptin as a mediator of obesity-induced hypertension. Curr Obes Rep. 2016;5(4):397-404. doi:10.1007/s13679-016-0231-x; Farcaş AD, Rusu A, Stoia MA, Vida-Simiti LA. Plasma leptin, but not resistin, TNF-α and adiponectin, is associated with echocardiographic parameters of cardiac remodeling in patients with coronary artery disease. Cytokine. 2018;103:46-49. doi:10.1016/j.cyto.2018.01.002; Csongrádi É, Káplár M, Nagy B Jr, Koch CA, Juhász A, Bajnok L, et al. Adipokines as atherothrombotic risk factors in obese subjects: Associations with haemostatic markers and common carotid wall thickness. Nutr Metab Cardiovasc Dis. 2017;27(6):571-580. doi:10.1016/j.numecd.2017.02.007; Everson-Rose SA, Barinas-Mitchell EJM, El Khoudary SR, Huang HH, Wang Q, Janssen I, et al. Adipokines and subclinical cardiovascular disease in post-menopausal women: Study of women’s health across the nation. J Am Heart Assoc. 2021;10(7):e019173. doi:10.1161/JAHA.120.019173; Varma B, Ogunmoroti O, Ndumele CE, Zhao D, Szklo M, Sweeney T, et al. Higher leptin levels are associated with coronary artery calcium progression: The Multi-Ethnic Study of Atherosclerosis (MESA). Diabet Epidemiol Manag. 2022;6:100047. doi:10.1016/j.deman.2021.100047; Raman P, Khanal S. Leptin in atherosclerosis: Focus on macrophages, endothelial and smooth muscle cells. Int J Mol Sci. 2021;22(11):5446. doi:10.3390/ijms22115446; Bobbert P, Jenke A, Bobbert T, Kühl U, Rauch U, Lassner D, et al. High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy. Eur J Heart Fail. 2012;14(11):1265-1275. doi:10.1093/eurjhf/hfs111; Puurunen VP, Kiviniemi A, Lepojärvi S, Piira OP, Hedberg P, Junttila J, et al. Leptin predicts short-term major adverse cardiac events in patients with coronary artery disease. Ann Med. 2017;49(5):448-454. doi:10.1080/07853890.2017.1301678; Bickel C, Schnabel RB, Zeller T, Lackner KJ, Rupprecht HJ, Blankenberg S, et al. Predictors of leptin concentration and association with cardiovascular risk in patients with coronary artery disease: Results from the AtheroGene study. Biomarkers. 2017;22(3-4):210-218. doi:10.3109/1354750X.2015.1130745; Ait Eldjoudi D, Cordero Barreal A, Gonzalez-Rodríguez M, Ruiz-Fernández C, Farrag Y, Farrag M, et al. Leptin in osteoarthritis and rheumatoid arthritis: Player or bystander? Int J Mol Sci. 2022;23(5):2859. doi:10.3390/ijms23052859; Lee YH, Bae SC. Circulating leptin level in rheumatoid arthritis and its correlation with disease activity: A meta-analysis. Z Rheumatol. 2016;75(10):1021-1027. doi:10.1007/s00393-016-0050-1; Kuo CY, Tsai TY, Huang YC. Insulin resistance and serum levels of adipokines in patients with systemic lupus erythematosus: A systematic review and meta-analysis. Lupus. 2020;29(9):1078-1084. doi:10.1177/0961203320935185; Villa N, Badla O, Goit R, Saddik SE, Dawood SN, Rabih AM, et al. Role of leptin in systemic lupus erythematosus: Is it still a mystery? Cureus. 2022;14(7):e26751. doi:10.7759/cureus.26751; Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, et al. 2010 rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010;62(9): 2569-2581. doi:10.1002/art.27584; Petri M, Orbai AM, Alarcón GS, Gordon C, Merrill JT, Fortin PR, et al. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum. 2012;64(8):2677-2686. doi:10.1002/art.34473; Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-419. doi:10.1007/BF00280883; Quevedo-Abeledo JC, Sánchez-Pérez H, Tejera-Segura B, de Armas-Rillo L, Ojeda S, Erausquin C, et al. Higher prevalence and degree of insulin resistance in patients with rheumatoid arthritis than in patients with systemic lupus erythematosus. J Rheumatol. 2021;48(3):339-347. doi:10.3899/jrheum.200435; Santos MJ, Vinagre F, Silva JJ, Gil V, Fonseca JE. Cardiovascular risk profile in systemic lupus erythematosus and rheumatoid arthritis: A comparative study of female patients. Acta Reumatol Port. 2010;35(3):325-332.; Chung CP, Oeser A, Solus JF, Gebretsadik T, Shintani A, Avalos I, et al. Inflammation-associated insulin resistance: Differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanisms. Arthritis Rheum. 2008;58(7):2105-2112. doi:10.1002/art.23600; Contreras-Haro B, Hernandez-Gonzalez SO, Gonzalez-Lopez L, Espinel-Bermudez MC, Garcia-Benavides L, Perez-Guerrero E, et al. Fasting triglycerides and glucose index: A useful screening test for assessing insulin resistance in patients diagnosed with rheumatoid arthritis and systemic lupus erythematosus. Diabetol Metab Syndr. 2019;11:95. doi:10.1186/s13098-019-0495-x; Guimarães MFBR, de Andrade MVM, Machado CJ, Vieira ÉLM, Pinto MRDC, et al. Leptin as an obesity marker in rheumatoid arthritis. Rheumatol Int. 2018;38(9):1671-1677. doi:10.1007/s00296-018-4082-5; La Cava A. Leptin in inflammation and autoimmunity. Cytokine. 2017;98:51-58. doi:10.1016/j.cyto.2016.10.011; Federico LE, Johnson TM, England BR, Wysham KD, George MD, Sauer B, et al. Circulating adipokines and associations with incident cardiovascular disease in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2023;75(4):768-777. doi:10.1002/acr.24885; Baker JF, England BR, George MD, Wysham K, Johnson T, Kunkel G, et al. Elevations in adipocytokines and mortality in rheumatoid arthritis. Rheumatology (Oxford). 2022;61(12):4924-4934. doi:10.1093/rheumatology/keac191; Marouen S, Barnetche T, Combe B, Morel J, Daïen CI. TNF inhibitors increase fat mass in inflammatory rheumatic disease: A systematic review with meta-analysis. Clin Exp Rheumatol. 2017;35(2):337-343.; Toussirot E. The Interrelations between biological and targeted synthetic agents used in inflammatory joint diseases, and obesity or body composition. Metabolites. 2020;10(3):107. doi:10.3390/metabo10030107; https://rsp.mediar-press.net/rsp/article/view/3361Test

الإتاحة: https://doi.org/10.47360/1995-4484-2023-339-348Test
https://doi.org/10.1136/ard.2010.135871Test
https://doi.org/10.1002/art.39136Test
https://doi.org/10.1002/art.20612Test
https://doi.org/10.1002/acr.20343Test
https://doi.org/10.1007/s00394-009-0017-yTest
https://doi.org/10.47360/1995-4484-2022-487-494Test
https://doi.org/10.1016/S2213-8587Test(18)30137-2
https://doi.org/10.1016/j.metabol.2021.154894Test
https://doi.org/10.3803/EnM.2020.301Test

View record in BASE

5

دورية أكاديمية

Comparative characteristics of the triglyceride-glucose index and the homeostatic index of insulin resistance in various forms of non-alcoholic fatty liver disease ; Сравнительная характеристика триглицеридглюкозного индекса и гомеостатического индекса инсулинорезистентности при разных формах неалкогольной жировой болезни печени

المؤلفون: A. A. Shipovskaya, I. V. Kurbatova, N. A. Larina, O. P. Dudanova, А. А. Шиповская, И. В. Курбатова, Н. А. Ларина, О. П. Дуданова

المساهمون: Работа выполнена при финансовой поддержке Министерств науки и высшего образования Российской Федерации по темам № FMEN-2022-0009 (№ г.р. 122031100064-4) и №0218-2019-0077.

المصدر: Meditsinskiy sovet = Medical Council; № 18 (2023); 59-67 ; Медицинский Совет; № 18 (2023); 59-67 ; 2658-5790 ; 2079-701X

مصطلحات موضوعية: HOMA-IR, liver steatosis, steatohepatitis, insulin resistance, triglyceride glucose index, стеатоз печени, стеатогепатит, инсулинорезистентность, триглицерид-глюкозный индекс

وصف الملف: application/pdf

العلاقة: https://www.med-sovet.pro/jour/article/view/7862/6983Test; Киселева ЕВ, Демидова ТЮ. Неалкогольная жировая болезнь печени и сахарный диабет 2 типа: проблема сопряженности и этапности развития. Ожирение и метаболизм. 2021;18(3):313–319. https://doi.org/10.14341/omet12758Test.; Лавренова ЕА, Драпкина ОМ. Инсулинорезистентность при ожирении: причины и последствия. Ожирение и метаболизм. 2020;17(1):48–55. https://doi.org/10.14341/omet9759Test.; Mu W, Cheng XF, Liu Y, Lv QZ, Liu GL, Zhang JG, Li XY. Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues. Front Pharmacol. 2019;9:1566. https://doi.org/10.3389/fphar.2018.01566Test.; Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord. 2008;6(4):299–304. https://doi.org/10.1089/met.2008.0034Test.; Guerrero-Romero F, Simental-Mendía LE, González-Ortiz M, Martínez-Abundis E, Ramos-Zavala MG, Hernández-González SO et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab. 2010;95(7):3347–3351. https://doi.org/10.1210/jc.2010-0288Test.; Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–419. https://doi.org/10.1007/BF00280883Test.; Locateli JC, Lopes WA, Simões CF, de Oliveira GH, Oltramari K, Bim RH et al. Triglyceride/glucose index is a reliable alternative marker for insulin resistance in South American overweight and obese children and adolescents. J Pediatr Endocrinol Metab. 2019;32(10):1163-1170. https://doi.org/10.1515/jpem-2019-0037Test.; Hameed EK. TyG index a promising biomarker for glycemic control in type 2 Diabetes Mellitus. Diabetes Metab Syndr. 2019;13(1):560–563. https://doi.org/10.1016/j.dsx.2018.11.030Test.; Lee SH, Kwon HS, Park YM, Ha HS, Jeong SH, Yang HK et al. Predicting the development of diabetes using the product of triglycerides and glucose: the Chungju Metabolic Disease Cohort (CMC) study. PLoS ONE. 2014;9(2):e90430. https://doi.org/10.1371/journal.pone.0090430Test.; Aslan Çin NN, Yardımcı H, Koç N, Uçaktürk SA, Akçil Ok M. Triglycerides/ high-density lipoprotein cholesterol is a predictor similar to the triglyceride-glucose index for the diagnosis of metabolic syndrome using International Diabetes Federation criteria of insulin resistance in obese adolescents: a cross-sectional study. J Pediatr Endocrinol Metab. 2020;33(6):777–784. https://doi.org/10.1515/jpem-2019-0310Test.; Tohidi M, Baghbani-Oskouei A, Ahanchi NS, Azizi F, Hadaegh F. Fasting plasma glucose is a stronger predictor of diabetes than triglyceride-glucose index, triglycerides/high-density lipoprotein cholesterol, and homeostasis model assessment of insulin resistance: Tehran Lipid and Glucose Study. Acta Diabetol. 2018;55(10):1067–1074. https://doi.org/10.1007/s00592-018-1195-yTest.; Мадянов ИВ. Косвенные способы оценки инсулинорезистентности при метаболическом синдроме. РМЖ. 2021;(2):10–12. Режим доступа https://www.rmj.ru/articles/endokrinologiya/Kosvennye_sposoby_ocenki_insulinorezistentnosti_pri_metabolicheskom_sindrome/?ysclid=lnvjinw19w534105634Test.; Руяткина ЛА, Руяткин ДС, Исхакова ИС, Щербакова ЛВ. Возможности оценки инсулинорезистентности по мере кластеризации метаболического синдрома у женщин в постменопаузе. Медицинский совет. 2019;(4):88–93. https://doi.org/10.21518/2079-701X-2019-4-88-93Test.; Sánchez-García A, Rodríguez-Gutiérrez R, Mancillas-Adame L, González-Nava V, Díaz González-Colmenero A, Solis RC et al. Diagnostic Accuracy of the Triglyceride and Glucose Index for Insulin Resistance: A Systematic Review. Int J Endocrinol. 2020;2020:4678526. https://doi.org/10.1155/2020/4678526Test.; Kitae A, Hashimoto Y, Hamaguchi M, Obora A, Kojima T, Fukui M. The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. Can J Gastroenterol Hepatol. 2019;2019:5121574. https://doi.org/10.1155/2019/5121574Test.; Huanan C, Sangsang L, Amoah AN, Yacong B, Xuejiao C, Zhan S et al. Relationship between triglyceride glucose index and the incidence of non-alcoholic fatty liver disease in the elderly: a retrospective cohort study in China. BMJ Open. 2020;10(11):e039804. https://doi.org/10.1136/bmjopen-2020-039804Test.; Bastard JP, Lavoie ME, Messier V, Prud’homme D, Rabasa-Lhoret R. Evaluation of two new surrogate indices including parameters not using insulin to assess insulin sensitivity/resistance in non-diabetic postmenopausal women: a MONET group study. Diabetes Metab. 2012;38(3):258–263. https://doi.org/10.1016/j.diabet.2012.01.004Test.; Vasques AC, Novaes FS, de Oliveira Mda S, Souza JR, Yamanaka A, Pareja JC et al. TyG index performs better than HOMA in a Brazilian population: a hyperglycemic clamp validated study. Diabetes Res Clin Pract. 2011;93(3):e98–e100. https://doi.org/10.1016/j.diabres.2011.05.030Test.; Мишина ЕЕ, Майоров АЮ, Богомолов ПО, Люсина ЕО, Буеверов АО. Ассоциация инсулинорезистентности и неалкогольной жировой болезни печени. Сахарный диабет. 2020;23(5):412–423. https://doi.org/10.14341/DM12234Test.; Dallio M, Sangineto M, Romeo M, Villani R, Romano AD, Loguercio C et al. Immunity as Cornerstone of Non-Alcoholic Fatty Liver Disease: The Contribution of Oxidative Stress in the Disease Progression. Int J Mol Sci. 2021;22(1):436. https://doi.org/10.3390/ijms22010436Test.; Lebeaupin C, Vallée D, Hazari Y, Hetz C, Chevet E, Bailly-Maitre B. Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease. J Hepatol. 2018;69(4):927–947. https://doi.org/10.1016/j.jhep.2018.06.008Test.; Metcalf MG, Higuchi-Sanabria R, Garcia G, Tsui CK, Dillin A. Beyond the cell factory: Homeostatic regulation of and by the UPRER. Sci Adv. 2020;6(29):eabb9614. https://doi.org/10.1126/sciadv.abb9614Test.; Yu L, Cai Y, Qin R, Zhao B, Li X. Association between triglyceride glucose index and abnormal liver function in both urban and rural Chinese adult populations: Findings from two independent surveys. Medicine (Baltimore). 2019;98(50):e18265. https://doi.org/10.1097/MD.0000000000018265Test.; Shojaie L, Iorga A, Dara L. Cell Death in Liver Diseases: A Review. Int J Mol Sci. 2020;21(24):9682. https://doi.org/10.3390/ijms21249682Test.; Radun R, Trauner M. Role of FXR in Bile Acid and Metabolic Homeostasis in NASH: Pathogenetic Concepts and Therapeutic Opportunities. Semin Liver Dis. 2021;41(4):461–475. https://doi.org/10.1055/s-0041-1731707Test.; Grzych G, Chávez-Talavera O, Descat A, Thuillier D, Verrijken A, Kouach M et al. NASH-related increases in plasma bile acid levels depend on insulin resistance. JHEP Rep. 2020;3(2):100222. https://doi.org/10.1016/j.jhepr.2020.100222Test.; Khan RS, Bril F, Cusi K, Newsome PN. Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease. Hepatology. 2019;70(2):711–724. https://doi.org/10.1002/hep.30429Test.; Zhao H, Huang X, Jiao J, Zhang H, Liu J, Qin W et al. Protein phosphatase 4 (PP4) functions as a critical regulator in tumor necrosis factor (TNF)-α-induced hepatic insulin resistance. Sci Rep. 2015;5:18093. https://doi.org/10.1038/srep18093Test.; Katsarou A, Moustakas II, Pyrina I, Lembessis P, Koutsilieris M, Chatzigeorgiou A. Metabolic inflammation as an instigator of fibrosis during non-alcoholic fatty liver disease. World J Gastroenterol. 2020;26(17):1993–2011. https://doi.org/10.3748/wjg.v26.i17.1993Test.; Fujii H, Imajo K, Yoneda M, Nakahara T, Hyogo H, Takahashi H et al. HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease. J Gastroenterol Hepatol. 2019;34(8):1390–1395. https://doi.org/10.1111/jgh.14595Test.; https://www.med-sovet.pro/jour/article/view/7862Test

الإتاحة: https://doi.org/10.21518/ms2023-378Test
https://doi.org/10.14341/omet12758Test
https://doi.org/10.14341/omet9759Test
https://doi.org/10.3389/fphar.2018.01566Test
https://doi.org/10.1089/met.2008.0034Test
https://doi.org/10.1210/jc.2010-0288Test
https://doi.org/10.1007/BF00280883Test
https://doi.org/10.1515/jpem-2019-0037Test
https://doi.org/10.1016/j.dsx.2018.11.030Test
https://doi.org/10.1371/journal.pone.0090430Test

View record in BASE

6

دورية أكاديمية

Association between adipokines and cardiac remodeling in obese patients in preclinical heart failure ; Ассоциация между адипокинами и ремоделированием сердца у пациентов с ожирением на доклинических стадиях сердечной недостаточности

المؤلفون: E. A. Lyasnikova, G. A. Matveev, T. I. Golikova, I. V. Derevitskii, A. V. Fedorov, E. Yu. Vasilyeva, A. Yu. Babenko, Е. А. Лясникова, Г. А. Матвеев, Т. И. Голикова, И. В. Деревицкий, А. В. Федоров, Е. Ю. Васильева, А. Ю. Бабенко

المساهمون: Исследование выполнено при финансовой поддержке Министерства науки и высшего образования Российской Федерации (соглашение №075-15-2022-301 от 20.04.2022).

المصدر: Meditsinskiy sovet = Medical Council; № 17 (2022); 80-91 ; Медицинский Совет; № 17 (2022); 80-91 ; 2658-5790 ; 2079-701X

مصطلحات موضوعية: гипертрофия левого желудочка, adiponectin, insulin resistance, HOMA-IR, inflammation, sST2, left ventricular hypertrophy, адипонектин, инсулинорезистентность, воспаление

وصف الملف: application/pdf

العلاقة: https://www.med-sovet.pro/jour/article/view/7114/6386Test; Badimon L., Bugiardini R., Cenko E., Cubedo J., Dorobantu M., Duncker D.J. et al. Position paper of the European Society of Cardiology-working group of coronary pathophysiology and microcirculation: obesity and heart disease. Eur Heart J. 2017;38(25):1951–1958. https://doi.org/10.1093/eurheartj/ehx181Test.; Heidenreich P.A., Bozkurt B., Aguilar D., Allen L.A., Byun J.J., Colvin M.M. et al. AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145(18):e895– e1032. https://doi.org/10.1161/CIR.0000000000001063Test.; Bozkurt B., Aguilar D., Deswal A., Dunbar S.B., Francis G.S., Horwich T. et al. Contributory Risk and Management of Comorbidities of Hypertension, Obesity, Diabetes Mellitus, Hyperlipidemia, and Metabolic Syndrome in Chronic Heart Failure: A Scientific Statement From the American Heart Association. Circulation. 2016;134(23):e535–e578. https://doi.org/10.1161/CIR.0000000000000450Test.; Prenner S.B., Mather P.J. Obesity and heart failure with preserved ejection fraction: A growing problem. Trends Cardiovasc Med. 2018;28(5):322–327. https://doi.org/10.1016/j.tcm.2017.12.003Test.; Albakri A. Obesity cardiomyopathy: a review of literature on clinical status and meta-analysis of diagnostic and clinical management. Med Clin Arch. 2018;2(3):1–13. https://doi.org/10.15761/MCA.1000134Test.; Abel E.D., Litwin S.E., Sweeney G. Cardiac remodeling in obesity. Physiol Rev. 2008;88(2):389–419. https://doi.org/10.1152/physrev.00017.2007Test.; Sletten A.C., Peterson L.R., Schaffer J.E. Manifestations and mechanisms of myocardial lipotoxicity in obesity. J Intern Med. 2018;284(5):478–491. https://doi.org/10.1111/joim.12728Test.; Ashrafian H., Athanasiou T., le Roux C.W. Heart remodelling and obesity: the complexities and variation of cardiac geometry. Heart. 2011;97(3):171–172. https://doi.org/10.1136/hrt.2010.207092Test.; Selthofer-Relatić K., Belovari T., Bijelić N., Kibel A., Rajc J. Presence of Intramyocardial Fat Tissue in the Right Atrium and Right Ventricle – Postmortem Human Analysis. Acta Clin Croat. 2018;57(1):122–129. https://doi.org/10.20471/acc.2018.57.01.15Test.; Packer M., Kitzman D.W. Obesity-Related Heart Failure With a Preserved Ejection Fraction: The Mechanistic Rationale for Combining Inhibitors of Aldosterone, Neprilysin, and Sodium-Glucose Cotransporter-2. JACC Heart Fail. 2018;6(8):633–639. https://doi.org/10.1016/j.jchf.2018.01.009Test.; Oh A., Okazaki R., Sam F., Valero-Muñoz M. Heart Failure With Preserved Ejection Fraction and Adipose Tissue: A Story of Two Tales. Front Cardiovasc Med. 2019;6:110. https://doi.org/10.3389/fcvm.2019.00110Test.; Packer M. Leptin-Aldosterone-Neprilysin Axis: Identification of Its Distinctive Role in the Pathogenesis of the Three Phenotypes of Heart Failure in People With Obesity. Circulation. 2018;137(15):1614–1631. https://doi.org/10.1161/CIRCULATIONAHA.117.032474Test.; Trayhurn P., Wood I.S. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans. 2005;33(Pt 5):1078–1081. https://doi.org/10.1042/BST0331078Test.; Bahrami H., Bluemke D.A., Kronmal R., Bertoni A.G., Lloyd-Jones D.M., Shahar E. et al. Novel metabolic risk factors for incident heart failure and their relationship with obesity: the MESA (Multi-Ethnic Study of Atherosclerosis) study. J Am Coll Cardiol. 2008;51(18):1775–1783. https://doi.org/10.1016/j.jacc.2007.12.048Test.; Rosen B.D., Cushman M., Nasir K., Bluemke D.A., Edvardsen T., Fernandes V. et al. Relationship between C-reactive protein levels and regional left ventricular function in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis. J Am Coll Cardiol. 2007;49(5):594–600. https://doi.org/10.1016/j.jacc.2006.09.040Test.; Wu H., Ballantyne C.M. Metabolic Inflammation and Insulin Resistance in Obesity. Circ Res. 2020;126(11):1549–1564. https://doi.org/10.1161/CIRCRESAHA.119.315896Test.; Witteles R.M., Fowler M.B. Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options. J Am Coll Cardiol. 2008;51(2):93–102. https://doi.org/10.1016/j.jacc.2007.10.021Test.; Cauwenberghs N., Knez J., Thijs L., Haddad F., Vanassche T., Yang W.Y. et al. Relation of Insulin Resistance to Longitudinal Changes in Left Ventricular Structure and Function in a General Population. J Am Heart Assoc. 2018;7(7):e008315. https://doi.org/10.1161/JAHA.117.008315Test.; Velagaleti R.S., Gona P., Chuang M.L., Salton C.J., Fox C.S., Blease S.J. et al. Relations of insulin resistance and glycemic abnormalities to cardiovascular magnetic resonance measures of cardiac structure and function: the Framingham Heart Study. Circ Cardiovasc Imaging. 2010;3(3):257–263. https://doi.org/10.1161/CIRCIMAGING.109.911438Test.; Shah R.V., Abbasi S.A., Heydari B., Rickers C., Jacobs D.R. Jr, Wang L. et al. Insulin resistance, subclinical left ventricular remodeling, and the obesity paradox: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2013;61(16):1698–1706. https://doi.org/10.1016/j.jacc.2013.01.053Test.; Wong C., Marwick T.H. Obesity cardiomyopathy: pathogenesis and pathophysiology. Nat Clin Pract Cardiovasc Med. 2007;4(8):436–443. https://doi.org/10.1038/ncpcardio0943Test.; Ghantous C.M., Azrak Z., Hanache S., Abou-Kheir W., Zeidan A. Differential Role of Leptin and Adiponectin in Cardiovascular System. Int J Endocrinol. 2015:534320. https://doi.org/10.1155/2015/534320Test.; Ebong I.A., Goff D.C. Jr, Rodriguez C.J., Chen H., Bertoni A.G. Mechanisms of heart failure in obesity. Obes Res Clin Pract. 2014;8(6):e540–548. https://doi.org/10.1016/j.orcp.2013.12.005Test.; Rajapurohitam V., Gan X.T., Kirshenbaum L.A., Karmazyn M. The obesityassociated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes. Circ Res. 2003;93(4):277–279. https://doi.org/10.1161/01.RES.0000089255.37804.72Test.; Smith C.C., Yellon D.M. Adipocytokines, cardiovascular pathophysiology and myocardial protection. Pharmacol Ther. 2011;129(2):206–219. https://doi.org/10.1016/j.pharmthera.2010.09.003Test.; Karmazyn M., Purdham D.M., Rajapurohitam V., Zeidan A. Leptin as a cardiac hypertrophic factor: a potential target for therapeutics. Trends Cardiovasc Med. 2007;17(6):206–211. https://doi.org/10.1016/j.tcm.2007.06.001Test.; Bantulà M., Roca-Ferrer J., Arismendi E., Picado C. Asthma and Obesity: Two Diseases on the Rise and Bridged by Inflammation. J Clin Med. 2021;10(2):169. https://doi.org/10.3390/jcm10020169Test.; Kamareddine L., Ghantous C.M., Allouch S., Al-Ashmar S.A., Anlar G., Kannan S. et al. Between Inflammation and Autophagy: The Role of Leptin-Adiponectin Axis in Cardiac Remodeling. J Inflamm Res. 2021;14:5349–5365. https://doi.org/10.2147/JIR.S322231Test.; Hall M.E., Harmancey R., Stec D.E. Lean heart: Role of leptin in cardiac hypertrophy and metabolism. World J Cardiol. 2015;7(9):511–524. https://doi.org/10.4330/wjc.v7.i9.511Test.; Woodward L., Akoumianakis I., Antoniades C. Unravelling the adiponectin paradox: novel roles of adiponectin in the regulation of cardiovascular disease. Br J Pharmacol. 2017;174(22):4007–4020. https://doi.org/10.1111/bph.13619Test.; Shibata R., Ouchi N., Ito M., Kihara S., Shiojima I., Pimentel D.R. et al. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med. 2004;10(12):1384–1389. https://doi.org/10.1038/nm1137Test.; Anthony S.R., Guarnieri A.R., Gozdiff A., Helsley R.N., Phillip Owens A., Tranter M. Mechanisms linking adipose tissue inflammation to cardiac hypertrophy and fibrosis. Clin Sci (Lond). 2019;133(22):2329–2344. https://doi.org/10.1042/CS20190578Test.; Norvik J.V., Schirmer H., Ytrehus K., Jenssen T.G., Zykova S.N., Eggen A.E. et al. Low adiponectin is associated with diastolic dysfunction in women: a cross-sectional study from the Tromsø Study. BMC Cardiovasc Disord. 2017;17(1):79. https://doi.org/10.1186/s12872-017-0509-2Test.; Biolo A., Shibata R., Ouchi N., Kihara S., Sonoda M., Walsh K., Sam F. Determinants of adiponectin levels in patients with chronic systolic heart failure. Am J Cardiol.;105(8):1147–1152. https://doi.org/10.1016/j.amjcard.2009.12.015Test.; Villarreal-Molina M.T., Antuna-Puente B. Adiponectin: anti-inflammatory and cardioprotective effects. Biochimie. 2012;94(10):2143–2149. https://doi.org/10.1016/j.biochi.2012.06.030Test.; López-Jaramillo P., Gómez-Arbeláez D., López-López J., López-López C., Martínez-Ortega J,. Gómez-Rodríguez A., Triana-Cubillos S. The role of leptin/ adiponectin ratio in metabolic syndrome and diabetes. Horm Mol Biol Clin Investig. 2014;18(1):37–45. https://doi.org/10.1515/hmbci-2013-0053Test.; Williams B., Mancia G., Spiering W., Agabiti Rosei E., Azizi M., Burnier M. et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018;39(33):3021–3104. https://doi.org/10.1093/eurheartj/ehy339Test.; Marwick T.H., Gillebert T.C., Aurigemma G., Chirinos J., Derumeaux G., Galderisi M. et al. Recommendations on the Use of Echocardiography in Adult Hypertension: A Report from the European Association of Cardiovascular Imaging (EACVI) and the American Society of Echocardiography (ASE). J Am Soc Echocardiogr. 2015;28(7):727–754. https://doi.org/10.1016/j.echo.2015.05.002Test.; McClatchey M.W., Cohen S.J., Reed F.M. The usefulness of matched pair randomization for medical practice-based research. Fam Pract Res J. 1992;12(3):235–243. Available at: https://pubmed.ncbi.nlm.nih.gov/1414427Test/.; Zhang Z. Introduction to machine learning: k-nearest neighbors. Ann Transl Med. 2016;4(11):218. https://doi.org/10.21037/atm.2016.03.37Test.; Liu T., Moore A. W., Gray A. New algorithms for efficient high-dimensional nonparametric classification. J Mach Learn Res. 2006;7(41):1135–1158. Available at: http://people.ee.duke.edu/~lcarin/liu06a.pdfTest.; Perego L., Pizzocri P., Corradi D., Maisano F., Paganelli M., Fiorina P. et al. Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: a potential role for leptin in mediating human left ventricular hypertrophy. J Clin Endocrinol Metab. 2005;90(7):4087–4093. https://doi.org/10.1210/jc.2004-1963Test.; Barouch L.A., Berkowitz D.E., Harrison R.W., O’Donnell C.P., Hare J.M. Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. Circulation. 2003;108(6):754–759. https://doi.org/10.1161/01.CIR.0000083716.82622.FDTest.; Hall M.E., Maready M.W., Hall J.E., Stec D.E. Rescue of cardiac leptin receptors in db/db mice prevents myocardial triglyceride accumulation. Am J Physiol Endocrinol Metab. 2014;307(3):E316–325. https://doi.org/10.1152/ajpendo.00005.2014Test.; Pladevall M., Williams K., Guyer H., Sadurní J., Falces C., Ribes A. et al. The association between leptin and left ventricular hypertrophy: a populationbased cross-sectional study. J Hypertens. 2003;21(8):1467–1473. https://doi.org/10.1097/00004872-200308000-00009Test.; Lieb W., Sullivan L.M., Aragam J., Harris T.B., Roubenoff R., Benjamin E.J., Vasan R.S. Relation of serum leptin with cardiac mass and left atrial dimension in individuals >70 years of age. Am J Cardiol. 2009;104(4):602–605. https://doi.org/10.1016/j.amjcard.2009.04.026Test.; Paduszyńska A., Sakowicz A., Banach M., Maciejewski M., Dąbrowa M., Bielecka-Dąbrowa A. Cardioprotective properties of leptin in patients with excessive body mass. Ir J Med Sci. 2020;189(4):1259–1265. https://doi.org/10.1007/s11845-020-02211-9Test.; Kamimura D., Suzuki T., Wang W., deShazo M., Hall J.E., Winniford M.D. et al. Higher plasma leptin levels are associated with reduced left ventricular mass and left ventricular diastolic stiffness in black women: insights from the Genetic Epidemiology Network of Arteriopathy (GENOA) study. Hypertens Res. 2018;41(8):629–638. https://doi.org/10.1038/s41440-018-0062-0Test.; Melhem S., Steven S., Taylor R., Al-Mrabeh A. Effect of Weight Loss by LowCalorie Diet on Cardiovascular Health in Type 2 Diabetes: An Interventional Cohort Study. Nutrients. 2021;13(5):1465. https://doi.org/10.3390/nu13051465Test.; Fujita Y., Kouda K., Ohara K., Nakamura H., Iki M. Leptin mediates the relationship between fat mass and blood pressure: The Hamamatsu Schoolbased health study. Medicine (Baltimore). 2019;98(12):e14934. https://doi.org/10.1097/MD.0000000000014934Test.; D’souza A.M., Neumann U.H., Glavas M.M., Kieffer T.J. The glucoregulatory actions of leptin. Mol Metab. 2017;6(9):1052–1065. https://doi.org/10.1016/j.molmet.2017.04.011Test.; Pereira S., Cline D.L., Glavas M.M., Covey S.D., Kieffer T.J. Tissue-Specific Effects of Leptin on Glucose and Lipid Metabolism. Endocr Rev. 2021;42(1):1–28. https://doi.org/10.1210/endrev/bnaa027Test.; Isidori A.M., Strollo F., Morè M., Caprio M., Aversa A., Moretti C. et al. Leptin and aging: correlation with endocrine changes in male and female healthy adult populations of different body weights. J Clin Endocrinol Metab. 2000;85(5):1954–1962. https://doi.org/10.1210/jcem.85.5.6572Test.; Sahu A. Minireview: A hypothalamic role in energy balance with special emphasis on leptin. Endocrinology. 2004;145(6):2613–2620. https://doi.org/10.1210/en.2004-0032Test.; Unger R.H. Hyperleptinemia: protecting the heart from lipid overload. Hypertension. 2005;45(6):1031–1034. https://doi.org/10.1161/01.HYP.0000165683.09053.02Test.; Faxén U.L., Hage C., Andreasson A., Donal E., Daubert J.C., Linde C. et al. HFpEF and HFrEF exhibit different phenotypes as assessed by leptin and adiponectin. Int J Cardiol. 2017;228:709–716. https://doi.org/10.1016/j.ijcard.2016.11.194Test.; Reinmann M., Meyer P. B-type natriuretic peptide and obesity in heart failure: a mysterious but important association in clinical practice. Cardiovasc Med. 2020;23:w02095. https://doi.org/10.4414/cvm.2020.02095Test.; Sarhene M., Wang Y., Wei J., Huang Y., Li M., Li L. et al. Biomarkers in heart failure: the past, current and future. Heart Fail Rev. 2019;24(6):867–903. https://doi.org/10.1007/s10741-019-09807-zTest.; Ghali R., Altara R., Louch W.E., Cataliotti A., Mallat Z., Kaplan A. et al. IL-33 (Interleukin 33)/sST2 Axis in Hypertension and Heart Failure. Hypertension. 2018;72(4):818–828. https://doi.org/10.1161/HYPERTENSIONAHA.118.11157Test.; Altara R., Ghali R., Mallat Z., Cataliotti A., Booz G.W., Zouein F.A. Conflicting vascular and metabolic impact of the IL-33/sST2 axis. Cardiovasc Res. 2018;114(12):1578–1594. https://doi.org/10.1093/cvr/cvy166Test.; Zeyda M., Wernly B., Demyanets S., Kaun C., Hämmerle M., Hantusch B. et al. Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue. Int J Obes (Lond). 2013;37(5):658–665. https://doi.org/10.1038/ijo.2012.118Test.; Ojji D.B., Opie L.H., Lecour S., Lacerda L., Adeyemi O., Sliwa K. Relationship between left ventricular geometry and soluble ST2 in a cohort of hypertensive patients. J Clin Hypertens (Greenwich). 2013;15(12):899–904. https://doi.org/10.1111/jch.12205Test.; Zhang Z., Xie Y., Shen B., Nie Y., Cao X., Xiang F., Zou J. Relationship between Soluble ST2 and Left Ventricular Geometry in Maintenance Hemodialysis Patients. Blood Purif. 2021;50(1):84–92. https://doi.org/10.1159/000508402Test.; Ibrahim N.E., Januzzi J.L. Jr. Established and Emerging Roles of Biomarkers in Heart Failure. Circ Res. 2018;123(5):614–629. https://doi.org/10.1161Test/ CIRCRESAHA.118.312706.; Lebedev D.A., Lyasnikova E.A., Vasilyeva E.Yu., Babenko A.Yu., Shlyakhto E.V. Type 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis. J Diabetes Res. 2020:6976153. https://doi.org/10.1155/2020/6976153Test.; Miller A.M. Role of IL-33 in inflammation and disease. J Inflamm (Lond). 2011;8(1):22. https://doi.org/10.1186/1476-9255-8-22Test.; Rana B.M.J., Jou E., Barlow J.L., Rodriguez-Rodriguez N., Walker J.A., Knox C. et al. A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue. J Exp Med. 2019;216(9):1999–2009. https://doi.org/10.1084/jem.20190689Test.; Zhou Z., Yan F., Liu O. Interleukin (IL)-33: an orchestrator of immunity from host defence to tissue homeostasis. Clin Transl Immunology. 2020;9(6):e1146. https://doi.org/10.1002/cti2.1146Test.; Celic V., Majstorovic A., Pencic-Popovic B., Sljivic A., Lopez-Andres N., Roy I. et al. Soluble ST2 Levels and Left Ventricular Structure and Function in Patients With Metabolic Syndrome. Ann Lab Med. 2016;36(6):542–549. https://doi.org/10.3343/alm.2016.36.6.542Test.; Tseng C.C.S., Huibers M.M.H., van Kuik J., de Weger R.A., Vink A., de Jonge N. The Interleukin-33/ST2 Pathway Is Expressed in the Failing Human Heart and Associated with Pro-fibrotic Remodeling of the Myocardium. J Cardiovasc Transl Res. 2018;11(1):15–21. https://doi.org/10.1007/s12265-017-9775-8Test.; Wu M.X., Wang S.H., Xie Y., Chen Z.T., Guo Q., Yuan W.L. et al. Interleukin-33 alleviates diabetic cardiomyopathy through regulation of endoplasmic reticulum stress and autophagy via insulin-like growth factor-binding protein 3. J Cell Physiol. 2021;236(6):4403–4419. https://doi.org/10.1002/jcp.30158Test.; https://www.med-sovet.pro/jour/article/view/7114Test