SCLERODERMA SYSTEMATICA WITH INTERSTITIAL LUNG LESION: COMPARATIVE CLINICAL CHARACTERISTICSWITH PATIENTS WITHOUT LUNG LESION
| العنوان: | SCLERODERMA SYSTEMATICA WITH INTERSTITIAL LUNG LESION: COMPARATIVE CLINICAL CHARACTERISTICSWITH PATIENTS WITHOUT LUNG LESION |
|---|---|
| المؤلفون: | Lyudmila Valeryevna Teplova, L P Ananyeva, V N Lesnyak, M N Starovoitova, O V Desinova, T A Nevskaya, E N Aleksandrova |
| المصدر: | Научно-практическая ревматология, Vol 48, Iss 3, Pp 41-47 (2010) |
| بيانات النشر: | IMA-PRESS LLC, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | medicine.medical_specialty, High-resolution computed tomography, Immunology, high-resolution computed tomography, Disease, Diseases of the musculoskeletal system, Gastroenterology, Scleroderma, chemistry.chemical_compound, Rheumatology, Internal medicine, Lactate dehydrogenase, Parenchyma, medicine, Immunology and Allergy, Respiratory system, scleroderma systematica, Lung, medicine.diagnostic_test, business.industry, interstitial lung lesion, medicine.disease, medicine.anatomical_structure, chemistry, RC925-935, Erythrocyte sedimentation rate, business |
| الوصف: | Objective. To compare disease history data and clinical and laboratory parameters in patients with scleroderma systematica (SDS) with high-resolution computed tomography (HRCT)-verified interstitial lung lesion (ILL) versus those without lung involvement. Subjects and methods. An examination was made in 138 patients with SDS who had been consecutively admitted in 2006-2008, female/male ratio, 124 : 14; limited : diffuse : mixed forms, 78 : 40 : 20; mean age, 47±13 years; median disease duration, 6 (2.5 11) years. The history data (occupational hazards, smoking, respiratory diseases) and clinical manifestations of SDS and laboratory data were studied. The diagnosis of ILL was established on the basis of chest HRCT. Results. According to HRCT data, the signs of varying ILL were found in 82% of the patients with SDS. The duration of SDS was similar in the patients with and without lung involvement; but the latter were younger at the time of disease onset. There were no significant differences between the groups compared in history data, clinical forms of SDS, the frequency of involvement of visceral organs and systems. Crepitation was heard only in the patients with ILL. The frequency of respiratory manifestations increased with a larger number of the involved lung segments. The prevalence of ILL was found to be positively correlated with age at the onset of SDS (r=0.29; p |
| اللغة: | Russian |
| تدمد: | 1995-4492 1995-4484 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63993bc59e5c28d5e2658719835c54b5Test https://rsp.mediar-press.net/rsp/article/view/580Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....63993bc59e5c28d5e2658719835c54b5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19954492 19954484 |
|---|