دورية أكاديمية
Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
| العنوان: | Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis |
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| المؤلفون: | Guerra, Sara Isabel da Silva, Mocciaro, Gabriele, Gastaldelli, Amalia |
| سنة النشر: | 2022 |
| المجموعة: | Universidade de Coimbra: Estudo Geral |
| مصطلحات موضوعية: | lipidomics, lipotoxicity, mitochondrial dysfunction, non-alcoholic fatty liver disease, Adipose Tissue, Humans, Insulin Resistance |
| الوصف: | The prevalence of non-alcoholic fatty liver disease (NAFLD) is now 25% in the general population but increases to more than 55% in subjects with obesity and/or type 2 diabetes. Simple steatosis (NAFL) can develop into more severe forms, that is non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma leading to death. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Portuguese |
| تدمد: | 0014-2972 1365-2362 |
| العلاقة: | #PLACEHOLDER_PARENT_METADATA_VALUE#; FOIE GRAS project (722619); mtFOIE GRAS project (734719); http://hdl.handle.net/10316/103991Test |
| DOI: | 10.1111/eci.13695 |
| الإتاحة: | https://doi.org/10.1111/eci.13695Test http://hdl.handle.net/10316/103991Test |
| حقوق: | info:eu-repo/semantics/embargoedAccess |
| رقم الانضمام: | edsbas.D70DFFDF |
| قاعدة البيانات: | BASE |
| تدمد: | 00142972 13652362 |
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| DOI: | 10.1111/eci.13695 |