دورية أكاديمية
Ozonized solutions favor the repair of experimentally induced skin wounds in rats
| العنوان: | Ozonized solutions favor the repair of experimentally induced skin wounds in rats |
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| المؤلفون: | Rafael C. Sanguanini, Mariana F. Bento, Evelyn de Oliveira, Emmanuel Arnhold, Mariana B.R. Faleiro, Leandro G. Franco, Moema P.C. Matos, Veridiana Maria B.D. Moura |
| المصدر: | Pesquisa Veterinária Brasileira, Vol 40, Iss 11, Pp 914-921 (2021) |
| بيانات النشر: | Colégio Brasileiro de Patologia Animal (CBPA) |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Ozonized water, wound healing, ozonized oil, ozone therapy, skin wounds, rats, Veterinary medicine, SF600-1100 |
| الوصف: | This study aimed to evaluate and compare the effects of ozonized solutions on tissue wound repair in rats. Treatments consisted of ozonized water (GA), 0.9% sodium chloride (GCL), ozonized oil (GO), and 0.2% allantoin cream (GAL). The morphometric evaluation showed that wounds of the GA group presented a higher degree of retraction (p<0.05) at three and eight days of treatment (37.96 and 84.81%, respectively). Picrosirius red staining showed that groups GA and GO presented higher deposition (p<0.05) of type I collagen at 15 and 22 days of treatment, respectively. The neovascularization was higher in wounds of group GO on days 3, 8, and 15 (p<0.05), with higher VEGF immunostaining. (p<0.05). Thus, ozonized water enhances wound retraction and assists in the maturation and remodeling phase, while ozonized oil promotes higher neovascularization during tissue repair and higher deposition of type I collagen from the third week of treatment. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Portuguese |
| تدمد: | 1678-5150 |
| العلاقة: | http://www.scielo.br/pdf/pvb/v40n11/1678-5150-pvb-40-11-914.pdfTest; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2020001100914&tlng=enTest; https://doaj.org/toc/1678-5150Test; https://doaj.org/article/df5c5501cd1b4d9797602b2804b77328Test |
| DOI: | 10.1590/1678-5150-pvb-6578 |
| الإتاحة: | https://doi.org/10.1590/1678-5150-pvb-6578Test https://doaj.org/article/df5c5501cd1b4d9797602b2804b77328Test |
| رقم الانضمام: | edsbas.CCD4668A |
| قاعدة البيانات: | BASE |
| تدمد: | 16785150 |
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| DOI: | 10.1590/1678-5150-pvb-6578 |