Dosagem de proteínas totais e desidrogenase lática para o diagnóstico de transudatos e exsudatos pleurais: redefinindo o critério clássico com uma nova abordagem estatística
| العنوان: | Dosagem de proteínas totais e desidrogenase lática para o diagnóstico de transudatos e exsudatos pleurais: redefinindo o critério clássico com uma nova abordagem estatística |
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| المؤلفون: | Antonio Monteiro da Silva Chibante, Gilberto Perez Cardoso, Bernardo Henrique Ferraz Maranhão, Cyro Teixeira da Silva Junior |
| المصدر: | Jornal Brasileiro de Pneumologia v.36 n.4 2010 Jornal Brasileiro de Pneumologia Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) instacron:SBPT |
| بيانات النشر: | Sociedade Brasileira de Pneumologia e Tisiologia, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Pleural effusion, Derrame pleural/diagnóstico, medicine.disease, University hospital, Gastroenterology, Surgery, chemistry.chemical_compound, chemistry, Lactate dehydrogenase, Daily practice, Internal medicine, Pleural fluid, Derrame pleural/classificação, Medicine, Exudatos e transudatos, business |
| الوصف: | OBJECTIVE: To propose a new classification criterion for the differentiation between pleural exudates and transudates-quantifying total proteins in pleural fluid (TP-PF) and lactate dehydrogenase in pleural fluid (LDH-PF) exclusively-as well as to compare this new criterion with the classical criterion in terms of diagnostic yield. METHODS: This was an observational, cross-sectional study with a within-subject design, comprising 181 patients with pleural effusion treated at two university hospitals in the state of Rio de Janeiro, Brazil, between 2003 and 2006. The diagnostic parameters included in the classical criterion were identified, as were those included in the new criterion. RESULTS: Of the 181 patients, 152 and 29 were diagnosed with pleural exudates and pleural transudates, respectively. For the classical criterion, the sensitivity, specificity, and accuracy for the diagnosis of pleural exudates were, respectively, 99.8%, 68.6%, and 94.5%, whereas the corresponding values for the diagnosis of pleural transudates were 76.1%, 90.1%, and 87.6%. For the new criterion (cut-off points set at 3.4 g/dL for TP-PF and 328.0 U/L for LDH-PF), the sensitivity, specificity, and accuracy for the diagnosis of exudates were, respectively, 99.4%, 72.6%, and 99.2%, whereas the corresponding values for the diagnosis of transudates were 98.5%, 83.4%, and 90.0%. The accuracy of the new criterion for the diagnosis of pleural exudates was significantly greater than was that of the classical criterion (p = 0.0022). CONCLUSIONS: The diagnostic yield was comparable between the two criteria studied. Therefore, the new classification criterion can be used in daily practice. |
| وصف الملف: | text/html |
| اللغة: | Portuguese |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d4c30d99e95fd1b6e99ab078875770Test http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132010000400012Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....66d4c30d99e95fd1b6e99ab078875770 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |