دورية أكاديمية
The role of glymphatic system in neurological diseases - literature review
| العنوان: | The role of glymphatic system in neurological diseases - literature review |
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| المؤلفون: | Karolina Niekurzak, Maciej Jędrak, Krzysztof Kania, Maciej Józefiak, Piotr Sobkiewicz, Joanna Kania |
| المصدر: | Journal of Education, Health and Sport, Vol 19, Iss 1 (2023) |
| بيانات النشر: | Kazimierz Wielki University, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Education LCC:Sports LCC:Medicine |
| مصطلحات موضوعية: | glymphatic system, aquaporin-4, Alzheimer's disease, Parkinson's disease, migraine, sleep, Education, Sports, GV557-1198.995, Medicine |
| الوصف: | Abstract Introduction: The glymphatic system is the equivalent of the lymphatic system in the brain. This system is responsible for the exchange of metabolism waste products between the cerebrospinal fluid and the interstitial fluid. The glymphatic system functions mainly during sleep, and this is when the removal of interstitial metabolism waste products take place. A proper diet and physical activity are also needed for the glymphatic system to work effectively. Abnormal function of the glymphatic system can contribute to the development of diseases of the central nervous system, including neurodegenerative diseases and migraine. Aim of the study: The aim of our study is to review the latest knowledge linking the glymphatic system with the pathogenesis of selected neurological diseases and other lifestyle-related factors such as sleep, diet and physical activity. The study included Alzheimer’s disease, Parkinson’s disease, migraines and ischemic stroke. Materials and methods: We have reviewed the literature available in the pubmed database using keywords: “glymphatic system”; “aquaporin-4”; “Alzheimer’s disease”; “Parkinson’s disease”; “migraines”; “sleep” Conclusions: The studies discussed here show a clear correlation between the glymphatic system and neurological diseases. The glymphatic system may definitely be involved in the pathophysiology of neurological disorders. A thorough investigation of this issue will help uncover potentially new strategies for the prevention and treatment of neurological diseases. Key words: glymphatic system; aquaporin-4; Alzheimer’s disease; Parkinson’s disease; migraine; sleep |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Spanish; Castilian Polish Russian Ukrainian |
| تدمد: | 2391-8306 |
| العلاقة: | https://apcz.umk.pl/JEHS/article/view/45689Test; https://doaj.org/toc/2391-8306Test |
| DOI: | 10.12775/JEHS.2023.19.01.013 |
| الوصول الحر: | https://doaj.org/article/187677d335d44b708c98041be5a8c5b3Test |
| رقم الانضمام: | edsdoj.187677d335d44b708c98041be5a8c5b3 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 23918306 |
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| DOI: | 10.12775/JEHS.2023.19.01.013 |