دورية أكاديمية
Glucose Lowering Effect of SGLT2 Inhibitors: A Review of Clinical Studies ; SGLT2 억제제의 혈당 강하 효과
| العنوان: | Glucose Lowering Effect of SGLT2 Inhibitors: A Review of Clinical Studies ; SGLT2 억제제의 혈당 강하 효과 |
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| المؤلفون: | Kim, HJ |
| المساهمون: | 105743, 김, 혜진 |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Hypoglycemic agents, Sodium glucose cotransporter 2, Type 2 diabetes mellitus |
| الوصف: | There are numerous glucose lowering agents in clinical use for type 2 diabetic patients, yet most do not achieve glycemic targets. Recently, inhibitors of the sodium glucose cotransporter 2 (SGLT2) have been developed, which show great potential of being a novel therapeutic option to treat type 2 diabetes. Many researches have turned their attention to the kidney as a target because renal glucose reabsorption is increased in type 2 DM. SGLT2 is a protein transporter that mediates glucose reabsorption from glomerular filtrates. In an insulinindependent manner, inhibition of SGLT2 increases urinary glucose excretion and decreases plasma glucose levels. To date, there are a few SGLT2 inhibiting agents being clinically studied both as a monotherapy and in combination with other antidiabetic agents. This review will focus on the efficacy of SGLT2 inhibitors based on clinical studies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Korean |
| تدمد: | 2233-7431 |
| العلاقة: | J022337431; http://repository.ajou.ac.kr/handle/201003/11482Test; https://synapse.koreamed.org/DOIx.php?id=10.4093/jkd.2014.15.3.146Test; The Journal of Korean Diabetes, 15(3). : 146-150, 2014 |
| DOI: | 10.4093/jkd.2014.15.3.146 |
| الإتاحة: | https://doi.org/10.4093/jkd.2014.15.3.146Test http://repository.ajou.ac.kr/handle/201003/11482Test |
| رقم الانضمام: | edsbas.11CE30B9 |
| قاعدة البيانات: | BASE |
| تدمد: | 22337431 |
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| DOI: | 10.4093/jkd.2014.15.3.146 |