التفاصيل البيبلوغرافية
| العنوان: |
USEFULNESS OF MEASUREMENT OF CD34-POSITIVE CELL COUNT AT MID-APHERESIS PRODUCT SAMPLING IN PERIPHERAL BLOOD STEM CELL COLLECTION. (English) |
| المؤلفون: |
Saori Nakabayashi, Minoru Kojima, Sakiho Takeoka, Nao Iwashita, Misato Tsubokura, Yuki Kase, Moemi Kasane, Noriko Takahashi, Sayaka Takeuchi, Chiaki Hayashi, Naoki Maezawa, Hidetomo Fukumoto, Wataru Takeda, Koji Izutsu, Chitose Ogawa, Hiromichi Matsushita, Takahiro Fukuda |
| المصدر: |
Japanese Journal of Transfusion & Cell Therapy / Nihon Yuketsu Saibo Chiryo Gakkaishi; 2023, Vol. 69 Issue 6, p634-640, 7p |
| مصطلحات موضوعية: |
BLOOD sampling, STEM cells, BLOOD cells, MEDIAN (Mathematics), COLLECTIONS |
| مستخلص: |
We retrospectively examined whether adjusting the amount of apheresis using the number of CD34-positive cells in the product during peripheral blood stem cell collection (PBSCH) led to optimal collection. A total of 52 subjects, including 28 allogeneic and 24 autologous PBSCH, were analyzed. We observed a correlation between the number of CD34-positive cells in the product during PBSCH (mid-apheresis) and after PBSCH (final product): total (R = 0.986), allogeneic (R = 0.973), autologous (R = 0.996). Additionally, the median value was 101% (range 79-129) in the allogeneic group and 123% (85-192) in the autologous group. The autologous group showed a significantly higher intermediate value. For events that occurred during collection, the value was significantly higher in the case group which waited 11 min or longer to start MNC collection. Although more appropriate PBSCH could be performed using the intermediate value, the final value was higher than the intermediate value with autologous PBSCH, and waiting 11 min or longer before starting MNC collection. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
