التفاصيل البيبلوغرافية
| العنوان: |
Uso degli α-bloccanti nell'ipertrofia prostatica benigna: il problema della "floppy iris syndrome". Risultati di uno studio caso-controllo per la valutazione del rischio pre-operatorio con la misura del diametro pupillare. (Italian) |
| العنوان البديل: |
α-blockers in benign prostatic hyperplasia: the problem of "floppy iris syndrome". Results of a case-control study to evaluate the surgical risk through the meausurement of pupil diameter. (English) |
| المؤلفون: |
Pavone, C., Abbadessa, D., Serretta, V., Cillino, V., Maggioni, A., El Rahman, D. Abed |
| المصدر: |
Urologia Journal; 2009, Vol. 76 Issue 1, p29-35, 7p |
| مصطلحات موضوعية: |
HYPERPLASIA treatment, BENIGN prostatic hyperplasia, PUPIL (Eye), ADRENERGIC beta blockers, BETA adrenoceptors, PUPILLOMETRY, HYPERPLASIA, PROSTATE hypertrophy, PHYSIOLOGY |
| مستخلص: |
OBJECTIVES. α-blockers are a group of α-adrenoceptor antagonists used by urologists to treat lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Recent studies have suggested that these drugs - tamsulosin in particular - are involved in the development of iris complications during phacoemulsification. The objective of this study is to investigate the effects of α-blockers - especially tamsulosin - on pupil diameter. MATERIALS AND METHODS. We measured the photopic, mesopic and post-dilatation pupil diameters in both eyes of 24 patients (46 eyes in total), 16 of them treated with α-blockers and 8 of them (16 eyes in total) not treated with any drugs (controls). RESULTS. All patients treated with tamsulosin showed minor photopic, mesopic and post-dilatation diameters compared to controls. Patients treated with other α-blockers did not show any difference compared to controls. CONCLUSIONS. Even if a small number of eyes was evaluated, our study shows that tamsulosin - through its selective effect on α1A receptors - is the most involved drug in the Intraoperative Floppy Iris Syndrome. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
