التفاصيل البيبلوغرافية
| العنوان: |
Efficacia a lungo termine della brachiterapia endocoronarica beta (32P) nel trattamento delle ristenosi intrastent ad elevato rischio. Risultati prospettici di un registro monocentrico |
| المؤلفون: |
Ortolani, Paolo, Marzocchi, Antonio, Gaiba, William, Neri, Stefano, Marrozzini, Cinzia, Palmerini, Tullio, Aquilina, Matteo, Corlianò, Leonardo, Lombardo, Enzo, Bunkheila, Feisal, Pini, Stefania, Sbarzaglia, Paolo, Barbieri, Enza, Branzi, Angelo, TAGLIERI, NEVIO |
| المساهمون: |
Ortolani, Paolo, Marzocchi, Antonio, Gaiba, William, Neri, Stefano, Marrozzini, Cinzia, Palmerini, Tullio, Aquilina, Matteo, Corlianò, Leonardo, Lombardo, Enzo, Bunkheila, Feisal, Pini, Stefania, Sbarzaglia, Paolo, Taglieri, Nevio, Barbieri, Enza, Branzi, Angelo |
| سنة النشر: |
2004 |
| المجموعة: |
IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: |
Cardiology and Cardiovascular Medicine |
| الوصف: |
BACKGROUND: The aim of the study was to evaluate, on single center prospective data, long-term angiographic and clinical results of intracoronary beta (32P) brachytherapy in "real world" patients with high-risk in-stent restenosis lesions. METHODS: Sixty-nine consecutive patients (77 lesions) with high-risk in-stent restenosis (mean lesion length 30.3 +/- 16.1 mm, pattern III-IV 57.2%, diabetes 33.3%) treated with percutaneous dilation procedures and beta-radiation therapy, underwent 7-month clinical and angiographic follow-up. RESULTS: One patient (1.4%) presented with procedural non-Q wave myocardial infarction. At a mean follow-up of 7 +/- 1.5 months, death was observed in 1 patient (1.4%) and non-Q wave myocardial infarction in 3 (4.3%) (in 2 patients, who prematurely discontinued antiplatelet therapy, caused by late coronary thrombosis). Seven-month binary angiographic restenosis occurred in 20 lesions (25.9%) (in-stent restenosis 11.6%). Target lesion and target vessel revascularization occurred in 20 (28.9%) and 21 (30.4%) patients. At follow-up only 12 (17.3%) patients presented with CCS class III-IV angina. After intracoronary beta brachytherapy angiographic restenosis occurred regardless of the vessel size, lesion length and ostial location. On the contrary a high restenosis rate was documented in obstructive lesions. CONCLUSIONS: As applied in routine clinical practice, radiation therapy is safe and effective in the treatment of high-risk in-stent restenosis. In spite of all that, total occlusion at baseline predicts late angiographic restenosis. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
STAMPA |
| اللغة: |
Italian |
| العلاقة: |
volume:4; issue:8 Suppl; firstpage:672; lastpage:681; numberofpages:10; journal:ITALIAN HEART JOURNAL; http://hdl.handle.net/11585/565492Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-1542702934 |
| الإتاحة: |
http://hdl.handle.net/11585/565492Test |
| رقم الانضمام: |
edsbas.6D914A34 |
| قاعدة البيانات: |
BASE |
