دورية أكاديمية
The strong correlation between right ventricular function evaluated by 3D echography and functional impairment in patients with dilated cardiomyopathy
| العنوان: | The strong correlation between right ventricular function evaluated by 3D echography and functional impairment in patients with dilated cardiomyopathy |
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| المؤلفون: | D'Andrea A., Gravino R., Salerno G., Padalino R., Riegler L., Scarafile R., Pezzullo E., Nunziata L., Romano M., Limongelli G., Bossone E., Pacileo G., Caso P., Russo M. G., Calabro R. |
| المساهمون: | D'Andrea, A., Gravino, R., Salerno, G., Padalino, R., Riegler, L., Scarafile, R., Pezzullo, E., Nunziata, L., Romano, M., Limongelli, G., Bossone, E., Pacileo, G., Caso, P., Russo, M. G., Calabro, R. |
| سنة النشر: | 2011 |
| المجموعة: | Università degli Studi della Campania "Luigi Vanvitelli": CINECA IRIS V: |
| مصطلحات موضوعية: | 3D echocardiography, Cardiac magnetic resonance, Cardiopulmonary test, Exercise capacity, Right ventricle |
| الوصف: | Objectives: The aim of the study was to detect if right ventricular (RV) ejection fraction assessed by real-time 3D echocardiography (RT3DE) could predict patients with dilated cardiomyopathy (DCM) with greater functional impairment in response to cardiopulmonary exercise. Materials and methods: 55 chronic heart failure patients with DCM (56.5 ± 9.1 years; 40 males; 30 ischaemic; NYHA class III: 40) and 30 healthy controls underwent both left ventricular (LV) and RV analysis by RT3DE. Post-processing software provided data of RT3DE systolic dyssynchrony index (SDI) of 16 LV segments, and of both LV and RV ejection fraction. Cardiac magnetic resonance was performed in a subgroup of 20 DCM patients to confirm RT3DE measurements. DCM patients underwent also bicycle cardiopulmonary exercise test with evaluation of VO 2 peak (percentage of the predicted value), VE/VCO 2 slope and circulatory power (CP). Results: In DCM patients mean LV ejection fraction was 29.8 ± 4.6%. RT3DE LV SDI was 8.4.4 ± 4.2, and RV ejection fraction was 51.3 ± 4.6%. By cardiopulmonary test, mean VO 2 peak was 15.2 ± 4.4 mL/kg/min, and mean CP was 2.1 ± 0.8. By univariable analysis, RV ejection fraction directly correlated with VO 2 peak % (r = 0,55; p < 0.0001) and inversely with VE/VCO 2 slope (r = -0.42; p < 0.001). By multivariable analysis, SDI (beta coefficient = -0.46; p < 0.001) and 3D RV ejection fraction (beta coefficient = 0.42; p < 0.001) emerged as the only independent determinant of VO 2 peak % during cardiopulmonary test. Conclusions: Impaired RV function in DCM patients is independently associated with worse ability to perform aerobic exercise. © 2011 Società Italiana di Ecografia Cardiovascolare. Published by Elsevier Srl. All rights reserved. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Italian |
| العلاقة: | volume:21; issue:3; firstpage:126; lastpage:134; numberofpages:9; journal:JOURNAL OF CARDIOVASCULAR ECHOGRAPHY; http://hdl.handle.net/11591/435988Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-80052999243 |
| DOI: | 10.1016/j.jcecho.2011.06.005 |
| الإتاحة: | https://doi.org/10.1016/j.jcecho.2011.06.005Test http://hdl.handle.net/11591/435988Test |
| رقم الانضمام: | edsbas.E30414B5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jcecho.2011.06.005 |
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