دورية أكاديمية
Portraying infective endocarditis: results of multinational ID-IRI study
| العنوان: | Portraying infective endocarditis: results of multinational ID-IRI study |
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| المؤلفون: | Erdem, Hakan, Puca, Edmond, Ruch, Yvon, Santos, Lurdes, Ghanem-Zoubi, Nesrin, Argemi, Xavier, Hansmann, Yves, Guner, Rahmet, Tonziello, Gilda, Mazzucotelli, Jean-Philippe, Como, Najada, Kose, Sukran, Batirel, Ayse, Inan, Asuman, Tulek, Necla, Pekok, Abdullah, Khan, Ejaz, Iyisoy, Atilla, Meric-Koc, Meliha, Kaya-Kalem, Ayse, Martins, Pedro, Hasanoglu, Imran, Silva-Pinto, André, Oztoprak, Nefise, Duro, Raquel, Almajid, Fahad, Dogan, Mustafa, Dauby, Nicolas, Gunst, Jesper, Tekin, Recep, Konopnicki, Deborah, Petrosillo, Nicola, Bozkurt, Ilkay, Wadi, Jamal, Popescu, Corneliu, Balkan, Ilker, Ozer-Balin, Safak, Zupanc, Tatjana, Cascio, Antonio, Dumitru, Irina, Erdem, Aysegul, Ersoz, Gulden, Tasbakan, Meltem, Ajamieh, Oday, Sirmatel, Fatma, Florescu, Simin, Gulsun, Serda, Ozkaya, Hacer, Sari, Sema, Tosun, Selma, Avci, Meltem, Cag, Yasemin, Celebi, Guven, Sagmak-Tartar, Ayse, Karakus, Sumeyra, Sener, Alper, Dedej, Arjeta, Oncu, Serkan, del Vecchio, Rosa, Ozturk-Engin, Derya, Agalar, Canan |
| المساهمون: | Virulence Bactérienne Précoce : fonctions cellulaires et contrôle de l'infection aigüe et subaigüe, Université de Strasbourg (UNISTRA), Virulence bactérienne précoce : fonctions cellulaires et contrôle de l'infection aiguë et subaiguë, Nanomédecine Régénérative (NanoRegMed), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| المصدر: | ISSN: 0934-9723. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2019 |
| المجموعة: | Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
| مصطلحات موضوعية: | Adolescent, Adult, Aged, 80 and over, Aortic Valve, Bacteria, Blood culture, Endocarditis, Bacterial, Female, Hospital Mortality, Humans, Infective endocarditis, Internationality, Male, Middle Aged, Mitral Valve, Native, Prosthesis-Related Infections, Prosthetic, S. aureus, Staphylococcal Infections, Viridans Streptococci, Young Adult, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology |
| الوصف: | Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients had pacemaker lead endocarditis, and 1 patient had catheter port endocarditis. Eighteen percent of NVE patients were hospital-acquired. PVE patients were classified as early-onset in 24.9%. A total of 385 (44.4%) patients had major embolic events, most frequently to the brain (n = 227, 26.3%). Blood cultures yielded pathogens in 766 (88.4%). In 101 (11.6%) patients, blood cultures were negative. Molecular testing of vegetations disclosed pathogens in 65 cases. Overall, 795 (91.7%) endocarditis patients had any identified pathogen. Leading pathogens (Staphylococcus aureus (n = 267, 33.6%), Streptococcus viridans (n = 149, 18.7%), enterococci (n = 128, 16.1%), coagulase-negative staphylococci (n = 92, 11.6%)) displayed substantial resistance profiles. A total of 132 (15.2%) patients had cardiac abscesses; 693 (79.9%) patients had left-sided endocarditis. Aortic (n = 394, 45.4%) and mitral valves (n = 369, 42.5%) were most frequently involved. Mortality was more common in PVE than NVE (NVE (n = 101, 16%), PVE (n = 49, 22.9%), p = 0.042). |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | French |
| العلاقة: | hal-02921185; https://hal.science/hal-02921185Test |
| DOI: | 10.1007/s10096-019-03607-x |
| الإتاحة: | https://doi.org/10.1007/s10096-019-03607-xTest https://hal.science/hal-02921185Test |
| رقم الانضمام: | edsbas.BE493144 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s10096-019-03607-x |
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