المؤلفون: Livia L Camargo, Augusto C. Montezano, William Fuller, Rheure Alves-Lopes, Vladimir Chubanov, Thomas Gudermann, ZhiGuo Zou, Xing Gao, Rhian M. Touyz, George S. Baillie, Francisco J. Rios, Jiayue Ling, Karla B Neves

المصدر: Clinical Science (London, England : 1979)

مصطلحات موضوعية: Vascular smooth muscle, Myocytes, Smooth Muscle, Primary Cell Culture, TRPM7, TRPM Cation Channels, Protein Serine-Threonine Kinases, Rats, Inbred WKY, Molecular Bases of Health & Disease, Muscle, Smooth, Vascular, CSK Tyrosine-Protein Kinase, Gefitinib, Epidermal growth factor, medicine, Morphogenesis, Animals, Humans, Magnesium, Phosphorylation, Protein kinase A, Receptor, Extracellular Signal-Regulated MAP Kinases, Cation Transport Proteins, Research Articles, EGFR inhibitors, EGF, Epidermal Growth Factor, Chemistry, General Medicine, Signaling, Cell biology, Mice, Inbred C57BL, HEK293 Cells, Cardiovascular System & Vascular Biology, vascular smooth muscle, Calcium, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215007187d18cdb20ed9765b8ae99130Test
http://europepmc.org/articles/PMC8299307Test

المؤلفون: Ran Zuo, Yajie Wang, Peng Chen, Cuicui Zhang, Li Lin

المصدر: Thoracic Cancer
Thoracic Cancer, Vol 11, Iss 9, Pp 2743-2748 (2020)

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Male, Lung Neoplasms, EGFR S768I, Afatinib, Case Report, Adenocarcinoma of Lung, Case Reports, lcsh:RC254-282, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Osimertinib, Epidermal growth factor receptor, Lung cancer, Protein Kinase Inhibitors, EGFR inhibitors, Aged, rare mutation, biology, business.industry, EGFR G724S, General Medicine, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, epidermal growth factor receptor (EGFR), ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Icotinib, Mutation, Cancer research, biology.protein, Adenocarcinoma, Female, business, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e4e5551796d49019216b64adb617baTest
http://europepmc.org/articles/PMC7471019Test

المؤلفون: Honeywell, Megan E

المساهمون: Michael J. Lee, Systems Biology

مصطلحات موضوعية: Cell death, Chemo-genetic profiling, CRISPR screening, MEDUSA, MEDUSA(GM), p53, MPT-dependent necrosis, Apoptosis, Non-apoptotic death, ELP complex, EGFR inhibitors, MCL1

العلاقة: http://hdl.handle.net/20.500.14038/52909Test; orcid:0000-0002-4894-8672

الإتاحة: https://doi.org/10.13028/d4ph-k012Test
https://doi.org/20.500.14038/52909Test
https://hdl.handle.net/20.500.14038/52909Test

المؤلفون: Baas, J.M.

المساهمون: Gelderblom, A.J., Guchelaar, H.J., Portielje, J.E.A. (Committee member), Smit, V.T.H.B.M. (Committee member), Hoeven, J.J.M. van der (Committee member), Bloemendal, H.J. (Committee member), Leiden University

مصطلحات موضوعية: Colorectal cancer, KRAS, Targeted therapy, EGFR inhibitors, Toxicity, Mutational analysis

وصف الملف: application/pdf

العلاقة: lucris-id: 1302862275; https://hdl.handle.net/1887/3719908Test

الإتاحة: https://hdl.handle.net/1887/3719908Test

المؤلفون: Siti Fatimah Zaharah Mustafa, Nor Elani Mat Nafi, Habsah Mohamad, Chia Hui Low, Khamsah Suryati Mohd

المصدر: Arabian Journal of Chemistry, Vol 15, Iss 1, Pp 103510-(2022)

مصطلحات موضوعية: Cytotoxic, Chemistry, Benzamide analogues, General Chemical Engineering, Estrogen receptor, General Chemistry, Epidermal growth factor receptor (EGFR), Small molecule, MCF-7, Docking (molecular), Cancer cell, Cancer research, Histone deacetylase II (HDAC II) enzymes, Cytotoxic T cell, Receptor, Janus kinase (JAK2) enzymes, QD1-999, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5fc0afce5fcef3d419f0c7159e17797Test
http://www.sciencedirect.com/science/article/pii/S1878535221005256Test

المؤلفون: Gabor Liposits, Per Pfeiffer

المصدر: Liposits, G & Pfeiffer, P 2022, ' Capecitabine in combination with panitumumab is not the treatment of choice in older patients with metastatic colorectal cancer ', Journal of Geriatric Oncology, vol. 13, no. 1, pp. 114-115 . https://doi.org/10.1016/j.jgo.2021.09.001Test

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Colorectal cancer, Panitumumab, medicine.disease, Capecitabine, Older patients, Internal medicine, Colonic Neoplasms, Humans, Medicine, Geriatrics and Gerontology, Colorectal Neoplasms, business, Aged, medicine.drug, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8795cd459b8da79c7abf074fd47b4f0dTest
https://portal.findresearcher.sdu.dk/da/publications/95d806d8-8ce7-4509-ad38-819c6ab011dbTest

المؤلفون: Hannah Zaryouh, Ines De Pauw, Marc Peeters, Jan B. Vermorken, Hasan Baysal, Filip Lardon, An Wouters

المصدر: Medicinal research reviews

مصطلحات موضوعية: Combination therapy, medicine.medical_treatment, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, medicine, Humans, Epidermal growth factor receptor, Protein kinase B, PI3K/AKT/mTOR pathway, 030304 developmental biology, EGFR inhibitors, Pharmacology, 0303 health sciences, biology, Cetuximab, business.industry, Squamous Cell Carcinoma of Head and Neck, Pharmacology. Therapy, medicine.disease, Head and neck squamous-cell carcinoma, ErbB Receptors, Drug Resistance, Neoplasm, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Molecular Medicine, Phosphatidylinositol 3-Kinase, business, Proto-Oncogene Proteins c-akt, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb7b7461bd3cbf687a71ab05dba8c45Test
https://hdl.handle.net/10067/1782160151162165141Test

المؤلفون: Kulbhushan Tikoo, Sandeep Singh, Nisha Sharma, Sajal Biswas, Gaurav Joshi, Raj Kumar, Tashvinder Singh, Manvendra Kumar, Zahid Rafiq Bhat, Sahil Arora

المصدر: Molecules
Volume 26
Issue 5
Molecules, Vol 26, Iss 1490, p 1490 (2021)

مصطلحات موضوعية: Lung Neoplasms, Pharmaceutical Science, 01 natural sciences, Analytical Chemistry, chemistry.chemical_compound, T790M, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Epidermal growth factor receptor, biology, Imidazoles, Gefitinib, ErbB Receptors, Molecular Docking Simulation, imidazo[1,2-a]quinoxaline, Chemistry (miscellaneous), Molecular Medicine, Erlotinib, medicine.drug, Antineoplastic Agents, mutant EGFR inhibitors, Article, lcsh:QD241-441, Erlotinib Hydrochloride, Inhibitory Concentration 50, Structure-Activity Relationship, anticancer agents, Quinoxaline, lcsh:Organic chemistry, Cell Line, Tumor, Quinoxalines, medicine, Humans, Physical and Theoretical Chemistry, Lung cancer, Protein Kinase Inhibitors, Cell Proliferation, 010405 organic chemistry, Organic Chemistry, non-covalent EGFR inhibitors, Wild type, Cancer, medicine.disease, 0104 chemical sciences, respiratory tract diseases, 010404 medicinal & biomolecular chemistry, chemistry, A549 Cells, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, Drug Screening Assays, Antitumor

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3beb00e5f569c499c49be90ff8547Test
http://europepmc.org/articles/PMC7967119Test

المؤلفون: Mohammed A.S. Abourehab, Bahaa G.M. Youssif, Alaa M. Alqahtani, Ahmed M. Gouda

المصدر: Molecules, Vol 26, Iss 6677, p 6677 (2021)
Molecules

مصطلحات موضوعية: Models, Molecular, synthesis, kinase inhibitor, EGFR, Drug Evaluation, Preclinical, Cancer therapy, Pharmaceutical Science, Organic chemistry, Antineoplastic Agents, Review, Chemistry Techniques, Synthetic, Ligands, anticancer, Binding, Competitive, Analytical Chemistry, Structure-Activity Relationship, QD241-441, Drug Development, Drug Discovery, Animals, Humans, Medicine, Physical and Theoretical Chemistry, Receptor, Cytotoxicity, Drug Approval, Protein Kinase Inhibitors, EGFR inhibitors, Kinase, business.industry, Clinical Studies as Topic, Metabolism, ErbB Receptors, Chemistry (miscellaneous), Egfr mutation, Cancer research, Molecular Medicine, Erlotinib, business, metabolism, Metabolic Networks and Pathways, Protein Binding, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cab09f6322fdad1faad6e006611d66cTest
https://www.mdpi.com/1420-3049/26/21/6677Test

المؤلفون: SANTARPIA, Mariacarmela, Rolfo, Christian, Peters, G. J., Leon, Leticia G., Giovannetti, Elisa

المساهمون: SANTARPIA, Mariacarmela, Rolfo, Christian, Peters, G. J., Leon, Leticia G., Giovannetti, Elisa

مصطلحات موضوعية: EGFR inhibitors, lung cancer, methodological challenges, pemetrexed, pharmacogenetic studies, Animals, Antineoplastic Agents, Carcinoma, Non-Small-Cell Lung, Drug Resistance, Neoplasm, Humans, Lung Neoplasms, Neoplasm Recurrence, Local, Patient Selection, Pharmacogenetics, Receptor, Epidermal Growth Factor, Survival Rate, Toxicology, Pharmacology

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26761638; info:eu-repo/semantics/altIdentifier/wos/WOS:000370753000002; volume:12; issue:3; firstpage:307; lastpage:317; numberofpages:11; journal:EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY; http://hdl.handle.net/11570/3097220Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84959151387

الإتاحة: https://doi.org/10.1517/17425255.2016.1141894Test
http://hdl.handle.net/11570/3097220Test