المؤلفون: Went, Molly, Sud, Amit, Försti, Asta, Halvarsson, Britt Marie, Weinhold, Niels, Kimber, Scott, van Duin, Mark, Thorleifsson, Gudmar, Holroyd, Amy, Johnson, David C., Li, Ni, Orlando, Giulia, Law, Philip J., Ali, Mina, Chen, Bowang, Mitchell, Jonathan S., Gudbjartsson, Daniel F., Kuiper, Rowan, Stephens, Owen W., Bertsch, Uta, Broderick, Peter, Campo, Chiara, Bandapalli, Obul R., Einsele, Hermann, Gregory, Walter A., Gullberg, Urban, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H., Jöckel, Karl Heinz, Johnsson, Ellinor, Kristinsson, Sigurður Y., Mellqvist, Ulf Henrik, Nahi, Hareth, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, da Silva Filho, Miguel Inacio, Thomsen, Hauke, Turesson, Ingemar, Wihlborg, Anna Karin, Hansson, Markus, Hemminki, Kari, Nilsson, Björn

المساهمون: Lunds universitet, Allmänmedicin, psykiatrisk epidemiologi och migration, Originator, Lund University, Family Medicine, Psychiatric Epidemiology and Migration, Originator, Lunds universitet, Avdelningen för hematologi och transfusionsmedicin, Originator, Lund University, Division of Hematology and Transfusion Medicine, Originator, Lunds universitet, Reumatologi och molekylär skelettbiologi, Originator, Lund University, Department of Rheumatology, Originator, Lunds universitet, BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation, Originator, Lund University, BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation, Originator

المصدر: Nature Communications. 10(1)

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology, Medicinska och farmaceutiska grundvetenskaper, Medicinsk genetik, Basic Medicine, Medical Genetics

الوصول الحر: http://lup.lub.lu.se/record/333566c3-5242-49f6-9f25-9be530487437Test
http://dx.doi.org/10.1038/s41467-018-08107-8Test

المؤلفون: Carmichael, Jonathan, Seymour, Frances, McIlroy, Graham, Tayabali, Sarrah, Amerikanou, Rosie, Feyler, Sylvia, Popat, Rakesh, Pratt, Guy, Parrish, Christopher, Ashcroft, A. John, Jackson, Graham H., Cook, Gordon

المصدر: Blood Cancer Journal ; volume 13, issue 1 ; ISSN 2044-5385

مصطلحات موضوعية: Oncology, Hematology

الإتاحة: https://doi.org/10.1038/s41408-023-00795-wTest
https://www.nature.com/articles/s41408-023-00795-w.pdfTest
https://www.nature.com/articles/s41408-023-00795-wTest

المؤلفون: Jones, John R., Cairns, David A., Menzies, Tom, Pawlyn, Charlotte, Davies, Faith E., Sigsworth, Rachel, Brioli, Annamaria, Jenner, Matthew W., Kaiser, Martin F., Olivier, Catherine, Reed, Molly, Drayson, Mark T., Owen, Roger G., Boyd, Kevin D., Cook, Gordon, Morgan, Gareth J., Jackson, Graham H.

المساهمون: Cancer Research UK

المصدر: eClinicalMedicine ; volume 62, page 102099 ; ISSN 2589-5370

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.eclinm.2023.102099Test
https://api.elsevier.com/content/article/PII:S2589537023002766?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2589537023002766?httpAccept=text/plainTest

المؤلفون: Maura, Francesco, Rajanna, Arjun Raj, Ziccheddu, Bachisio, Poos, Alexandra M, Derkach, Andriy, Maclachlan, Kylee, Durante, Michael, Diamond, Benjamin, Papadimitriou, Marios, Davies, Faith, Boyle, Eileen M, Walker, Brian, Hultcrantz, Malin, Silva, Ariosto, Hampton, Oliver, Teer, Jamie K, Siegel, Erin M, Bolli, Niccolò, Jackson, Graham H, Kaiser, Martin, Pawlyn, Charlotte, Cook, Gordon, Kazandjian, Dickran, Stein, Caleb, Chesi, Marta, Bergsagel, Leif, Mai, Elias K, Goldschmidt, Hartmut, Weisel, Katja C, Fenk, Roland, Raab, Marc S, Van Rhee, Fritz, Usmani, Saad, Shain, Kenneth H, Weinhold, Niels, Morgan, Gareth, Landgren, Ola

المصدر: J Clin Oncol ; ISSN:1527-7755 ; Volume:42 ; Issue:11

العلاقة: https://doi.org/10.1200/JCO.23.01277Test; https://pubmed.ncbi.nlm.nih.gov/38194610Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095887Test/

الإتاحة: https://doi.org/10.1200/JCO.23.01277Test
https://pubmed.ncbi.nlm.nih.gov/38194610Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095887Test/

المؤلفون: Jenner, Matthew W, Pawlyn, Charlotte, Davies, Faith E, Menzies, Tom, Hockaday, Anna, Olivier, Catherine, Jones, John R, Karunanithi, Kamaraj, Lindsay, Jindriska, Kishore, Bhuvan, Cook, Gorden, Drayson, Mark T, Kaiser, Martin F, Owen, Roger G, Gregory, Walter, Cairns, David A, Morgan, Gareth, Jackson, Graham H

وصف الملف: application/pdf

العلاقة: http://sro.sussex.ac.uk/id/eprint/111060/1/Br%20J%20Haematol%20-%202022%20-%20Jenner%20-%20The%20addition%20of%20vorinostat%20to%20lenalidomide%20maintenance%20for%20patients%20with%20newly%20diagnosed.pdfTest; Jenner, Matthew W, Pawlyn, Charlotte, Davies, Faith E, Menzies, Tom, Hockaday, Anna, Olivier, Catherine, Jones, John R, Karunanithi, Kamaraj, Lindsay, Jindriska, Kishore, Bhuvan, Cook, Gorden, Drayson, Mark T, Kaiser, Martin F, Owen, Roger G, Gregory, Walter, Cairns, David A, Morgan, Gareth and Jackson, Graham H (2022) The addition of vorinostat to lenalidomide maintenance for patients with newly diagnosed multiple myeloma of all ages: results from ‘Myeloma XI’, a multicentre, open-label, randomised, phase III trial. British Journal of Haematology. pp. 1-13. ISSN 0007-1048

الإتاحة: https://doi.org/10.1111/bjh.18600Test
http://sro.sussex.ac.uk/id/eprint/111060Test/
http://sro.sussex.ac.uk/id/eprint/111060/1/Br%20J%20Haematol%20-%202022%20-%20Jenner%20-%20The%20addition%20of%20vorinostat%20to%20lenalidomide%20maintenance%20for%20patients%20with%20newly%20diagnosed.pdfTest

المؤلفون: Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K.

المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-021-27679-6Test
https://www.nature.com/articles/s41467-021-27679-6.pdfTest
https://www.nature.com/articles/s41467-021-27679-6Test

المؤلفون: Cook, Gordon, Pawlyn, Charlotte, Cairns, David A, Jackson, Graham H

المصدر: The Lancet Healthy Longevity ; volume 3, issue 11, page e729-e730 ; ISSN 2666-7568

مصطلحات موضوعية: Family Practice, Psychiatry and Mental health, Geriatrics and Gerontology, Health (social science)

الإتاحة: https://doi.org/10.1016/s2666-7568Test(22)00218-5
https://api.elsevier.com/content/article/PII:S2666756822002185?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2666756822002185?httpAccept=text/plainTest

المؤلفون: Lin, Wei Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovani, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf Karsten, Gilkes, Amanda, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan, Allan, James M.

المساهمون: HUS Comprehensive Cancer Center, University Management, Helsinki University Hospital Area, Department of Oncology, Hematologian yksikkö

مصطلحات موضوعية: 3111 Biomedicine, HUMAN-LEUKOCYTE ANTIGEN, IMMUNE ESCAPE, CLONAL EVOLUTION, GENE-MUTATIONS, OLDER PATIENTS, RISK, CANCER, HLA, HIF-1-ALPHA, AML

وصف الملف: application/pdf

العلاقة: This work was funded by Blood Cancer UK (to JMA; #06002 and #13044). The Hungarian AML study was funded by the Hungarian National Research, Development and Innovation Office (NKFIH) (NVKP_16-1-2016-0004), a Momentum grant (LP-95021) from the Hungarian Academy of Sciences and EU’s Horizon 2020 research and innovation program under grant agreement No. 739593. The KORA study was initiated and financed by the Helmholtz Zentrum München—German Research Center for Environmental Health, which is funded by the German Federal Ministry of Education and Research (BMBF) and by the State of Bavaria. KORA research was supported within the Munich Center of Health Sciences (MC-Health), Ludwig-Maximilians-Universität, as part of LMUinnovativ. The recruitment of cases via the Catholic University of Rome was funded by Progetto AIRC 5permille Mynerva. DN is an endowed Professor of the Deutsche Jose Carreras Leukaemie Stiftung (DJCLS H 03/01) and is funded by the H.W. & J. Hector fund, Baden Wuerttemberg and the Dr. Rolf M. Schwiete Fund, Mannheim. MM is employed by the Munich Leukemia Laboratory and TH is part owner of the Munich Leukemia Laboratory. We are grateful to the Newcastle University Biobank (https://www.ncl.ac.uk/biobanksTest/) for providing samples. Collection of patient samples and associated clinico-pathological information was undertaken with written informed consent. All studies were conducted in accordance with the Declaration of Helsinki and received local institutional review board or national research ethics approval (Supplementary Table 9). Specifically, this research has been conducted using the UK Biobank Resource (Application #16583, James Allan). MRC/NCRI AML 11 trial, AML 12 trial and the UK Leukaemia Research Fund (LLR) population-based case–control study of adult acute leukemia received multicenter research ethics committee approval54,55,75. Research ethics committee approval was given to the Newcastle Haematology Biobank (07/H0906/109 + 5) and the AML genome-wide association study in the UK (06/q1108/92, BH136664 (7078)). AML cases and controls for Samples from the Hungarian AML patients were obtained during the standard diagnostic workup at the Hematology Divisions of the 1st and 3rd Department of Internal Medicine, Semmelweis University, Budapest, following ethical approval from the Local Ethical Committee (REF TUKEB-1552012) and the Hungarian Medical Research Council (REF 45371-2/2016/EKU). Saliva and fibroblast samples from Austrian AML patients were collected at the Division of Hematology, Medical University of Graz, Graz, Austria76. The diagnosis of AML was made in accordance with World Health Organisation guidelines.; Lin , W Y , Fordham , S E , Hungate , E , Sunter , N J , Elstob , C , Xu , Y , Park , C , Quante , A , Strauch , K , Gieger , C , Skol , A , Rahman , T , Sucheston-Campbell , L , Wang , J , Hahn , T , Clay-Gilmour , A I , Jones , G L , Marr , H J , Jackson , G H , Menne , T , Collin , M , Ivey , A , Hills , R K , Burnett , A K , Russell , N H , Fitzgibbon , J , Larson , R A , Le Beau , M M , Stock , W , Heidenreich , O , Alharbi , A , Allsup , D J , Houlston , R S , Norden , J , Dickinson , A M , Douglas , E , Lendrem , C , Daly , A K , Palm , L , Piechocki , K , Jeffries , S , Bornhäuser , M , Röllig , C , Altmann , H , Ruhnke , L , Kunadt , D , Wagenführ , L , Cordell , H J , Darlay , R , Andersen , M K , Fontana , M C , Martinelli , G , Marconi , G , Sanz , M A , Cervera , J , Gómez-Seguí , I , Cluzeau , T , Moreilhon , C , Raynaud , S , Sill , H , Voso , M T , Lo-Coco , F , Dombret , H , Cheok , M , Preudhomme , C , Gale , R E , Linch , D , Gaal-Wesinger , J , Masszi , A , Nowak , D , Hofmann , W K , Gilkes , A , Porkka , K , Milosevic Feenstra , J D , Kralovics , R , Grimwade , D , Meggendorfer , M , Haferlach , T , Krizsán , S , Bödör , C , Stölzel , F , Onel , K & Allan , J M 2021 , ' Genome-wide association study identifies susceptibility loci for acute myeloid leukemia ' , Nature Communications , vol. 12 , no. 1 , 6233 . https://doi.org/10.1038/s41467-021-26551-xTest; ORCID: /0000-0003-4112-5902/work/104212645; 85118442520; c5527ec5-ec3a-4404-8d63-1c21154fdd43; http://hdl.handle.net/10138/337099Test; 000712910500011

الإتاحة: http://hdl.handle.net/10138/337099Test

المؤلفون: Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovani, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf-Karsten, Gilkes, Amanda, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan, Allan, James M.

وصف الملف: application/pdf

العلاقة: https://orca.cardiff.ac.uk/id/eprint/146279/1/GILKES,%20MANDY%20-%20Genome-wide%20association%20study%20identifies.pdfTest; Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovani, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf-Karsten, Gilkes, Amanda https://orca.cardiff.ac.uk/view/cardiffauthors/A062527N.htmlTest, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan and Allan, James M. 2021. Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. Nature Communications 12 (1) , 6233. 10.1038/s41467-021-26551-x https://doi.org/10.1038/s41467-021-26551-xTest file https://orca.cardiff.ac.uk/id/eprint/146279/1/GILKES,%20MANDY%20-%20Genome-wide%20association%20study%20identifies.pdfTest

الإتاحة: https://doi.org/10.1038/s41467-021-26551-xTest
https://orca.cardiff.ac.uk/id/eprint/146279Test/
https://orca.cardiff.ac.uk/id/eprint/146279/1/GILKES,%20MANDY%20-%20Genome-wide%20association%20study%20identifies.pdfTest

المؤلفون: Jackson, Graham H, Pawlyn, Charlotte, Cairns, David A, de Tute, Ruth M, Hockaday, Anna, Collett, Corinne, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Rocci, Alberto, Snowden, John A, Jenner, Matthew W, Cook, Gordon, Russell, Nigel H, Drayson, Mark T, Gregory, Walter M, Kaiser, Martin F, Owen, Roger G, Davies, Faith E, Morgan, Gareth J

مصطلحات موضوعية: QW Microbiology. Immunology, QZ Pathology. Oncology, WH Haemic and lymphatic systems. Haematology

وصف الملف: text

العلاقة: http://www.repository.uhblibrary.co.uk/id/eprint/3867/1/journal.pmed.1003454.pdfTest; Jackson, Graham H, Pawlyn, Charlotte, Cairns, David A, de Tute, Ruth M, Hockaday, Anna, Collett, Corinne, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Rocci, Alberto, Snowden, John A, Jenner, Matthew W, Cook, Gordon, Russell, Nigel H, Drayson, Mark T, Gregory, Walter M, Kaiser, Martin F, Owen, Roger G, Davies, Faith E and Morgan, Gareth J (2021) Carfilzomib, lenalidomide, dexamethasone, and cyclophosphamide (KRdc) as induction therapy for transplant-eligible, newly diagnosed multiple myeloma patients (Myeloma XI+): Interim analysis of an open-label randomised controlled trial. PLoS medicine, 18 (1). e1003454. ISSN 1549-1676. This article is available to all UHB staff and students login using a UHB Athens Account. Register for Athens here - https://openathens.nice.org.ukTest/

الإتاحة: https://doi.org/10.1371/journal.pmed.1003454Test
http://www.repository.uhblibrary.co.uk/id/eprint/3867Test/
http://medicine.plosjournals.orgTest/
http://www.repository.uhblibrary.co.uk/id/eprint/3867/1/journal.pmed.1003454.pdfTest