المؤلفون: Apel, Christina, Kümmerer, Klaus, Sudheshwar, Akshat, Nowack, Bernd, Som, Claudia, Colin, Catherine, Walter, Lutz, Breukelaar, Johan, Meeus, Marcel, Ildefonso, Beatriz, Petrovykh, Dmitri, Elyahmadi, Chaima, Huttunen-Saarivirta, Elina, Dierckx, Ann, Devic, Anne Chloé, Valsami-Jones, Eva, Brennan, Maurice, Rocca, Cris, Scheper, Johanna, Strömberg, Emma, Soeteman-Hernández, Lya G.

المصدر: Apel , C , Kümmerer , K , Sudheshwar , A , Nowack , B , Som , C , Colin , C , Walter , L , Breukelaar , J , Meeus , M , Ildefonso , B , Petrovykh , D , Elyahmadi , C , Huttunen-Saarivirta , E , Dierckx , A , Devic , A C , Valsami-Jones , E , Brennan , M , Rocca , C , Scheper , J , Strömberg , E & Soeteman-Hernández , L G 2024 , ' Safe-and-sustainable-by-design : State of the art approaches and lessons learned from ....

مصطلحات موضوعية: By-design, Innovation process, Lifecycle, Safety and sustainability, SSbD concept, Value chain perspective, /dk/atira/pure/core/keywords/559804261, Chemistry

الوصف: Safe-and-sustainable-by-design (SSbD) is central in the European Chemicals Strategy for Sustainability, yet a common understanding of what SSbD is in concept and in practice is still needed. A comparison of current SSbD descriptions and approaches was made and lessons learned were derived from value chain discussions (packaging, textile, construction, automotive, energy materials, electronics, and fragrances value chains) to help provide input on how to implement SSbD in practice. Five important building blocks were identified: design, data, risk and sustainability governance, competencies, and social and corporate strategic needs. Other lessons learned include the identification of the biggest safety and sustainability challenges in a lifecycle-thinking approach towards the development of purpose-driven innovations, and connecting trans-disciplinary experts to the innovation process, already from the early phases. A clear understanding of what SSbD is and how to implement the SSbD framework is needed with clear procedures and incentives to support the industrial sector, especially SMEs.

الإتاحة: https://doi.org/10.1016/j.cogsc.2023.100876Test
http://fox.leuphana.de/portal/de/publications/safeandsustainablebydesignTest(45190b2c-3380-4483-aea1-fb954708fc41).html
http://www.scopus.com/inward/record.url?scp=85179896471&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/77bbd711-1a53-31d4-a9fa-b4eef86ab2efTest/

المؤلفون: Puhlmann, Neele, Vidaurre, Rodrigo, Kümmerer, Klaus

المصدر: Puhlmann , N , Vidaurre , R & Kümmerer , K 2024 , ' Designing greener active pharmaceutical ingredients : Insights from pharmaceutical industry into drug discovery and development ' , European Journal of Pharmaceutical Sciences , vol. 192 , 106614 . https://doi.org/10.1016/j.ejps.2023.106614Test

مصطلحات موضوعية: API, Environment, Experts, Feasibility, Interview, Sustainable, /dk/atira/pure/core/keywords/559804261, Chemistry

الوصف: Active pharmaceutical ingredients (APIs), their metabolites and transformation products (TPs) are found as pollutants in the environment. They can impact human and environmental health. To address this issue, an efficient, long-term prevention strategy could be the design of APIs that have less impact on the natural environment, i.e. the design of greener APIs, by the implementation of environmental parameters into the drug discovery and development process (also abbreviated R&D for ‘research and development’). Our study aimed to evaluate the feasibility of the design of greener APIs based on insights from drug design experts working in large, research-based pharmaceutical companies. The feasibility evaluation also identified needs and incentives for process modification. For this purpose, 30 R&D and environmental experts from seven globally active pharmaceutical companies were interviewed along a structured questionnaire. Main findings are that the interviewed experts saw manifold opportunities to include properties rendering APIs greener in different stages along the R&D process. This implementation would be favoured by the fact that the pharmaceutical R&D process is very flexible and relies on balancing multiple parameters. Furthermore, some API properties that reduce environmental risks were considered compatible with common desirable properties for application. Environmental properties should be considered early during R&D, i.e. when molecules are screened and optimized. It has been found that availability of suitable in silico models and in vitro assays is crucial for this environmental consideration. Their attributes, e.g. throughput and costs, determine at which process stage they can be successfully applied. An intensified exchange between R&D and environmental experts within and outside companies would push the industrial application of the benign by design approach for APIs forward. Collaboration across pharmaceutical companies, authorities, and academia is seen as highly ...

الإتاحة: https://doi.org/10.1016/j.ejps.2023.106614Test
http://fox.leuphana.de/portal/de/publications/designing-greener-active-pharmaceutical-ingredientsTest(0555a1c9-7810-4736-82ba-c388d5fc1af1).html
http://www.scopus.com/inward/record.url?scp=85175447711&partnerID=8YFLogxKTest

المؤلفون: Jentzsch, Franziska, Kümmerer, Klaus, Olsson, Oliver

المصدر: Jentzsch , F , Kümmerer , K & Olsson , O 2023 , ' Status quo on identified transformation products of organic ultraviolet filters and their persistence ' , International Journal of Cosmetic Science , vol. 45 , no. S1 , pp. 101-126 . https://doi.org/10.1111/ics.12908Test

مصطلحات موضوعية: /dk/atira/pure/core/keywords/559804261, Chemistry, abiotic/ biotic processes, suncare/ UV protection, fate, Micropollutants, stability

الوصف: Organic micropollutants of concern—including organic UV filters (UVF)—are getting increasing attention. Personal care products such as sunscreens or cosmetic articles often contain large quantities of UVF. These substances enter the environment either directly (during outdoor activities) or indirectly (via sewages from households). Therefore, the removal or degradation of UVF by natural or technical treatment processes is important to understand. UVF are often incompletely removed and transformed to side products of incomplete mineralization by abiotic and biotic processes. An extensive overview on transformation products (TPs) is essential to systematically identify knowledge gaps and to derive research needs. While there are many reviews on the UVF themselves, the number of reviews which focus on their TPs is limited. Consequently, this review gives an overview on the latest findings regarding TPs of UVF. In this publication, known TPs of UVF, which were formed during abiotic and biotic processes, are reviewed. Target substances were defined and a literature database was reviewed for studies on TPs of the target substances. The first list of studies was shortened stepwise, thus generating a final list of studies which contained only the relevant studies. Since biodegradation is one of the most important pathways for removal of organic compounds from the environment, this review presents an overview on known TPs of organic UVF and their biodegradability, which determines their environmental fate. In this way, all identified TPs of UVF were listed and checked for information on their biodegradability. A total of 2731 records of studies were assessed. Forty-two studies, which assessed 46 processes that lead to the formation of identified TPs, were included in this review. One hundred and seventyseven different TPs resulting from 11 different UVF were identified. Little to no data on the biodegradability was found for TPs. This indicates a severe lack of data on the biodegradability of TPs of organic UVF ...

الإتاحة: https://doi.org/10.1111/ics.12908Test
http://fox.leuphana.de/portal/de/publications/status-quo-on-identified-transformation-products-of-organic-ultraviolet-filters-and-their-persistenceTest(2c370d10-2629-4b3f-a87d-7b11a877678b).html
http://www.scopus.com/inward/record.url?scp=85173777391&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/b82c6646-3ec5-38f5-a88d-57ff7fbe10aeTest/

المؤلفون: Lichtinger, Anne, Poller, Maximilian J., Türck, Julian, Schröder, Olaf, Garbe, Thomas, Krahl, Jürgen, Singer, Anja, Jakob, Markus, Albert, Jakob

المصدر: Lichtinger , A , Poller , M J , Türck , J , Schröder , O , Garbe , T , Krahl , J , Singer , A , Jakob , M & Albert , J 2023 , ' Nile Red as a Fluorescence Marker and Antioxidant for Regenerative Fuels ' , Energy Technology , vol. 11 , no. 11 , 2300260 . https://doi.org/10.1002/ente.202300260Test

مصطلحات موضوعية: antioxidants, climate policy, climate-neutral, e-fuels, fluorescence markers, oxidation, /dk/atira/pure/core/keywords/559804261, Chemistry

الوصف: This article contributes to the ongoing dialogue regarding the future application of renewable e-fuels as part of a holistic solution to the energy crisis. In order to be able to continue using internal combustion engines in a sustainable manner, it must be ensured that these engines are operated exclusively with renewable, CO 2 -neutral fuels. One way to achieve this is the use of a fluorescence sensor in the vehicle in combination with fuels that are labeled with a fluorescence marker. This study presents an investigation into the use of the benzophenoxazine dye Nile red as a fluorescent marker for distinguishing fossil from renewable fuels. In addition to assessing the stability of the fluorescent marker against thermo-oxidative aging, the study probes its antioxidative impact on fuel aging, by comparing unlabeled and with Nile red labeled aged fuels. Furthermore, an examination of fuel-specific parameters underscores the positive effect of Nile red on fuel stability. A comparison with the antioxidant butylated hydroxytoluene confirms the antioxidant effect of Nile red.

الإتاحة: https://doi.org/10.1002/ente.202300260Test
http://fox.leuphana.de/portal/de/publications/nile-red-as-a-fluorescence-marker-and-antioxidant-for-regenerative-fuelsTest(f29a4ce9-c7d4-4147-b529-17f511bd02c6).html
http://www.scopus.com/inward/record.url?scp=85171540824&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/320731b5-6258-309d-8929-1fc35415c3a9Test/

المؤلفون: Rücker, Christoph, Winkelmann, Magnus, Kümmerer, Klaus

المصدر: Rücker , C , Winkelmann , M & Kümmerer , K 2023 , ' Are Si–C bonds formed in the environment and/or in technical microbiological systems? ' , Environmental Science and Pollution Research , vol. 30 , no. 39 , pp. 91492-91500 . https://doi.org/10.1007/s11356-023-28528-3Test

مصطلحات موضوعية: Biotrickling filter, Bond enthalpy, Decamethylcyclopentasiloxane, Dimethylsilanediol, GC retention time, Hexamethyldisiloxane, Octamethylcyclotetrasiloxane, /dk/atira/pure/core/keywords/559804261, Chemistry

الوصف: Organosiloxanes are industrially produced worldwide in millions of tons per annum and are widely used by industry, professionals, and consumers. Some of these compounds are PBT (persistent, biaccumulative and toxic) or vPvB (very persistent and very bioaccumulative). If organosiloxanes react at all in the environment, Si–O bonds are hydrolyzed or Si–C bonds are oxidatively cleaved, to result finally in silica and carbon dioxide. In strong contrast and very unexpectedly, recently formation of new Si–CH 3 bonds from siloxanes and methane by the action of microorganisms under mild ambient conditions was proposed (in landfills or digesters) and even reported (in a biotrickling filter, 30 °C). This is very surprising in view of the harsh conditions required in industrial Si–CH 3 synthesis. Here, we scrutinized the pertinent papers, with the result that evidence put forward for Si–C bond formation from siloxanes and methane in technical microbiological systems is invalid, suggesting such reactions will not occur in the environment where they are even less favored by conditions. The claim of such reactions followed from erroneous calculations and misinterpretation of experimental results. We propose an alternative explanation of the experimental observations, i.e., the putative observation of such reactions was presumably due to confusion of two compounds, hexamethyldisiloxane and dimethylsilanediol, that elute at similar retention times from standard GC columns.

الإتاحة: https://doi.org/10.1007/s11356-023-28528-3Test
http://fox.leuphana.de/portal/de/publications/are-sic-bonds-formed-in-the-environment-andor-in-technical-microbiological-systemsTest(94934e0f-70b6-4892-b14a-78d94327e74e).html
http://www.scopus.com/inward/record.url?scp=85165454766&partnerID=8YFLogxKTest

المؤلفون: Atzler, Frank, Türck, Julian, Türck, Ralf, Krahl, Jürgen

المصدر: Atzler , F , Türck , J , Türck , R & Krahl , J 2023 , ' The Energy Situation in the Federal Republic of Germany : Analysis of the Current Situation and Perspectives for a Non-Fossil Energy Supply ' , Energies , vol. 16 , no. 12 , 4569 . https://doi.org/10.3390/en16124569Test

مصطلحات موضوعية: bioFuels, biomass, defossilation, eFuels, energy storage, energy supply, energy transition, energy transport, mobility, regenerative energy, /dk/atira/pure/core/keywords/energieforschung, Energy research, /dk/atira/pure/core/keywords/559804261, Chemistry

الوصف: Formulating energy policies at national, European, and global levels is extremely challenging. The move away from fossil fuels is associated with a variety of technological, economic, and social implications, each of which is subject to dynamic changes and societal scrutiny and can hardly be predicted with certainty. Therefore, a fact-based assessment for the path to a sustainable green energy future is sought out in this paper, using the road-based mobility sector of the Federal Republic of Germany as an example. The analysis performed in this paper is built on publicly accessible, reputable sources like DESTATIS and EUROSTAT. In addition, some very simple calculations were made, e.g., on the potential for wind and photovoltaic energy within Germany. Such an analysis needs to start with the overall energy consumption of any one country. A basic assumption of the paper is that the energy system of the future will be based to a large extent on electricity and its storage in chemical energy. It is assumed that, in addition to hydrogen, liquid energy sources will play a significant role due to the simplicity of their logistics and the subsequent implications on cost. Examples of green, electricity-based fuels with great potential are methanol, methane, and ammonia. Additionally, biomass plays an important role, either for direct use as a fuel or as a source of non-fossil carbon. Today, biofuels, i.e., biodiesel and bioethanol, deliver the largest contribution to climate protection in the EU transport sector. The main goal—the reduction of greenhouse gas emissions—often collides with geopolitical circumstances or national political necessities. This includes, for example, the current world market situation and its national impacts caused by the Russian attack on Ukraine. The prospect for a green, sustainable, and defossilized energy supply are discussed in this context. The paper concludes that a defossilized world energy supply and trade based on renewable electricity and its derivatives, eHydrogen and refuels, and ...

الإتاحة: https://doi.org/10.3390/en16124569Test
http://fox.leuphana.de/portal/de/publications/the-energy-situation-in-the-federal-republic-of-germanyTest(cecd7edb-ad27-41bf-a8d0-01b7506b1dbd).html
http://www.scopus.com/inward/record.url?scp=85163859342&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/d22ebc63-4f2b-3086-9e9c-344d6839e5a4Test/

المؤلفون: Türck, Julian, Schmitt, Fabian, Anthofer, Lukas, Türck, Ralf, Ruck, Wolfgang, Krahl, Jürgen

المصدر: Türck , J , Schmitt , F , Anthofer , L , Türck , R , Ruck , W & Krahl , J 2023 , ' Extension of Biodiesel Aging Mechanism–the Role and Influence of Methyl Oleate and the Contribution of Alcohols Through the Use of Solketal ' , ChemSusChem , vol. 16 , no. 17 , e202300263 . https://doi.org/10.1002/cssc.202300263Test

مصطلحات موضوعية: biodiesel aging, epoxide-dependent oligomerization, Prileschajew reaction, solketal, /dk/atira/pure/core/keywords/559804261, Chemistry, /dk/atira/pure/core/keywords/energieforschung, Energy research

الوصف: The energy crisis and dependence on fossil fuels forces societies to develop alternative pathways to secure energy supplies. Therefore, non-fossil fuels such as biofuels and e-fuels can help counteract the resulting demand for existing combustion engines. However, biofuels, like biodiesel, have disadvantages in terms of oxidation stability. In general, aging of biodiesel is a complex mechanism due to interaction of various components. In order to develop an ideal fuel, the mechanism must be understood in full detail. In this work, an attempt is made to simplify the system by using methyl oleate as a biodiesel model component. In addition, other fuel components of interest such as alcohols and their respective acids help to clarify the aging mechanism. This work used isopropylidene glycerol (solketal) as the main alcohol, 1-octanol and octanoic acid. A holistic biodiesel aging scheme was developed by using generated data and evaluating the role of acids. They epoxidize unsaturated fatty acid via Prileschajev reactions. In addition, the role of epoxides in oligomerization reactions is confirmed. Moreover, the alcohols show that the suppression of oligomerization can be achieved by the reaction with methyl oleate. The alcohol-dependent aging products were determined by quadrupole time-of-flight (Q-TOF) mass spectrometry.

الإتاحة: https://doi.org/10.1002/cssc.202300263Test
http://fox.leuphana.de/portal/de/publications/extension-of-biodiesel-aging-mechanismthe-role-and-influence-of-methyl-oleate-and-the-contribution-of-alcohols-through-the-use-of-solketalTest(adff203c-04bd-48e0-8230-c4c5fb8a2d18).html
http://www.scopus.com/inward/record.url?scp=85164524262&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/b5ec5954-7fef-357a-9176-3c807282f91dTest/

المؤلفون: Watts, Beatriz A., Zago, Valéria C. Palmeira, Gopakumar, Lakshmi, Ghazaryan, Karen, Movsesyan, Hasmik

المصدر: Watts , B A , Zago , V C P , Gopakumar , L , Ghazaryan , K & Movsesyan , H 2023 , ' Uncharted risk measures for the management of sustainable mining ' , Integrated Environmental Assessment and Management , vol. 19 , no. 4 , pp. 949-960 . https://doi.org/10.1002/ieam.4769Test

مصطلحات موضوعية: /dk/atira/pure/core/keywords/559804261, Chemistry, Biomass valorization, Community involvement, Mining, Risk management, Tailing mining Facilities

الوصف: Governments commit to ensuring the welfare of their citizens by drafting and enforcing regulations that ultimately ensure the sustainability of mining. This study contributes to improving the sustainability of mining throughout the mine's lifecycle until the final destination of the mining products. We propose recommendations that address the sustainability of mining from a global perspective, framed around the United Nations Sustainable Development Goals (SDGs), following waste hierarchy with Common Agricultural Policies, and policies from the Green Deal on climate, energy, transport, and taxation. Tailings are the most significant source of environmental impact in mining operations and, therefore, must comply with controlling regulations through Tailings Management Facilities (TMFs). However, there have been several mining accidents involving TMFs worldwide. The recommendations begin during planning, preconstruction, and construction with practices such as fair consultations, tax revenue fairness, and mandatory insurance. The operation and management support parallel industries to mining and supporting health and education. Emergency planning involves the surrounding communities in mock drills and environmental monitoring. In the closure and rehabilitation, remediation technologies such as phytoremediation, carbon sequestration incentives, and biomass valorization are recommended. Finally, supporting a circular economy by prioritizing ethical consumption, resource reduction, material recovery, and replacing toxic minerals and materials from the start with “benign by design” is recommended. The strategies involve stakeholders directly or indirectly related to the mining companies' contamination and demonstrate a commitment to the SDGs, offering a holistic perspective on scientific, social, and regulatory issues. Integr Environ Assess Manag 2023;19:949–960.

الإتاحة: https://doi.org/10.1002/ieam.4769Test
http://fox.leuphana.de/portal/de/publications/uncharted-risk-measures-for-the-management-of-sustainable-miningTest(00fd54f6-8b48-47e3-ac6a-1a2abc585c7d).html
http://www.scopus.com/inward/record.url?scp=85152028232&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/e8b3b72a-1bfd-36bc-bddd-a0f4a0affa31Test/

المؤلفون: Türck, Julian, Schmitt, Fabian, Anthofer, Lukas, Lichtinger, Anne, Türck, Ralf, Ruck, Wolfgang, Krahl, Jürgen

المصدر: Türck , J , Schmitt , F , Anthofer , L , Lichtinger , A , Türck , R , Ruck , W & Krahl , J 2023 , ' Oxidation Kinetics of Neat Methyl Oleate and as a Blend with Solketal ' , Energies , vol. 16 , no. 7 , 3253 . https://doi.org/10.3390/en16073253Test

مصطلحات موضوعية: alcohol influence, biodiesel aging, methyl oleate, oxidation kinetics, sequence of aging products, solketal, /dk/atira/pure/core/keywords/559804261, Chemistry, /dk/atira/pure/core/keywords/energieforschung, Energy research

الوصف: The complexity of biodiesel aging has shown that the mechanism needs further research. The rate of aging product formation and associated interactions can help improve fuel quality. Since biodiesel is a multicomponent system and constant changes occur in the chemical environment, which interactions yield which products must be shown in more detail. Particularly under observation was the correlation between peroxides and epoxides. In addition, it is critical that the influence and interactions of new drop-in fuel candidates be investigated. In this work, the kinetics of the formation of aging products of methyl oleate (C18:1) are studied. The aim was to reduce the complexity in order to be able to make more precise and detailed statements about the mechanism. Ketones, acids, peroxide, and epoxide values were recorded. A distinction is made between pure methyl oleate and mixtures with 3 wt% isopropylidene glycerine (solketal). After solketal decomposed in the blends, the aging process showed changes. The influence of solketal resulted in a higher number of acids and epoxides over time. It implied that peroxides are not necessarily the precursor of epoxides. In summary, correlation and solketal’s influence showed that a sequence of aging products could be detected.

الإتاحة: https://doi.org/10.3390/en16073253Test
http://fox.leuphana.de/portal/de/publications/oxidation-kinetics-of-neat-methyl-oleate-and-as-a-blend-with-solketalTest(984e4805-22dd-4467-b4bf-a03205cc181f).html
http://www.scopus.com/inward/record.url?scp=85152517159&partnerID=8YFLogxKTest

المؤلفون: Zuin Zeidler, Vânia G.

المصدر: Zuin Zeidler , V G 2024 , ' Sustainable chemistry and food systems lessons-the same procedure as every year? ' , Science (New York, N.Y.) , vol. 383 , no. 6683 , eado2352 . https://doi.org/10.1126/science.ado2352Test

مصطلحات موضوعية: /dk/atira/pure/core/keywords/559804261, Chemistry

الوصف: "Dinner for One," a short black-and-white video performed in English from the 1960s, has become a cherished tradition in several German-speaking and Scandinavian countries, broadcast on TV every New Year's Eve for decades and gaining newfound popularity on social media among members of Generation Z. The narrative follows a British butler, James, whose employer, Miss Sophie, celebrates her 90th birthday as she has for many years by inviting her closest friends to dinner, though they have long since passed away. When asked by James throughout the dinner "The same procedure as last year?" while soup, fish, chicken, and fruit are being served, each with its corresponding beverage, Miss Sophie replies, "The same procedure as every year." But although it may be beloved as a work of comedic fiction, the same procedure as every year, the "business as usual" approach, is not sustainable in the real world when it comes to the food on our plates.

الإتاحة: https://doi.org/10.1126/science.ado2352Test
http://fox.leuphana.de/portal/de/publications/sustainable-chemistry-and-food-systems-lessonsthe-same-procedure-as-every-yearTest(b44a7700-fb7f-436a-8d7f-eb9c44ce0868).html
http://www.scopus.com/inward/record.url?scp=85184792584&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/ce866af9-78be-385f-bf7a-f9f2b49facf0Test/